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Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful tumor markers in identifying tumor cells with diagnostic tests and are potential candidates for use in cancer therapy. The field of cancer immunology studies such topics.

Transfection of eukaryontic cells with linear polynucleotides by electroporation

ActiveUS7547551B2High-efficiency non-viral transfectionEfficient loadingVertebrate cellsArtificial cell constructsGene deliveryDendritic cell

The present invention provides an improved method for gene delivery in eukaryotic cells by electroporation, preferably in human hematopoietic cells, particular dendritic cells. The method of the invention is superior to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for gene delivery, including tumor antigen loading of dendritic cells.

Transfection of eukaryontic cells with linear polynucleotides by electroporation

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Owner:UNIVERSITY OF ANTWERP

1 results about "Tumor antigen" patented technology

Transfection of eukaryontic cells with linear polynucleotides by electroporation

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