Traditional Chinese medicine extract, preparation method thereof and application to preparation of gastric cancer drug

A technology of extracts and traditional Chinese medicines, applied in the directions of drug combinations, pharmaceutical formulations, medical raw materials derived from ferns/filamentous plants, etc. inhibitory effect

Inactive Publication Date: 2016-03-09
杨美娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0007] At present, there are many kinds of drugs for treating gastric cancer on the market, and the side effects of western medicine are large, while the effect of existing traditional Chinese medicine is not very significant

Method used

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  • Traditional Chinese medicine extract, preparation method thereof and application to preparation of gastric cancer drug
  • Traditional Chinese medicine extract, preparation method thereof and application to preparation of gastric cancer drug
  • Traditional Chinese medicine extract, preparation method thereof and application to preparation of gastric cancer drug

Examples

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[0021] Example 1

[0022] The traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 30 parts of glaucoma, 30 parts of Tongjing grass, 15 parts of cat feces melon, and 28 parts of tongueless dog flower.

[0023] The preparation method of above-mentioned Chinese medicine extract, concrete preparation steps are as follows:

[0024] (1) Washing, drying, pulverizing and sieving each crude drug respectively, placing it in an extraction tank, adding distilled water, the mass ratio of material to liquid is 1:10, and extracting under pressure for 4 times at 100 ° C, and the pressure is controlled at 8 Atmospheric pressure, extract 3h each time, and combine the extracts to obtain extract A;

[0025] (2) soaking the extract A in 12 times ethanol and refluxing for 3 times, filtering and concentrating to a relative density of 1.10-1.15, and freeze-drying to obtain the extract C;

[0026] (3) Dissolve the above-mentioned extract C in an appropr

Example Embodiment

[0028] Example 2

[0029] The traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 35 parts of glaucoma, 25 parts of Tongjingcao, 20 parts of cat feces melon, and 26 parts of tongueless dog flower.

[0030] The preparation method of above-mentioned Chinese medicine extract, concrete preparation steps are as follows:

[0031] (1) Washing, drying, pulverizing and sieving each crude drug respectively, placing it in an extraction tank, adding distilled water, the mass ratio of material to liquid is 1:11, and extracting under pressure for 4 times at 100 ° C, the pressure is controlled at 8 Atmospheric pressure, extract 3h each time, and combine the extracts to obtain extract A;

[0032] (2) soaking the extract A in 14 times of ethanol and refluxing for 4 times, filtering and concentrating to a relative density of 1.10-1.15, and freeze-drying to obtain the extract C;

[0033] (3) Dissolve the above-mentioned extract C in an appropriate

Example Embodiment

[0035] Example 3

[0036] The traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 40 parts of glaucoma, 20 parts of Tongjing grass, 25 parts of cat feces melon, and 24 parts of tongueless dog flower.

[0037] The preparation method of above-mentioned Chinese medicine extract, concrete preparation steps are as follows:

[0038] (1) Washing, drying, pulverizing and sieving each crude drug respectively, placing it in an extraction tank, adding distilled water, the mass ratio of material to liquid is 1:12, extracting under pressure for 4 times at 100 ° C, and the pressure is controlled at 8 Atmospheric pressure, extract 3h each time, and combine the extracts to obtain extract A;

[0039] (2) soak the extract A in 15 times of ethanol and reflux for 5 times, filter and concentrate to a relative density of 1.10-1.15, and freeze-dry to obtain the extract C;

[0040] (3) Dissolve the above-mentioned extract C in an appropriate amount of

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Abstract

The invention discloses a traditional Chinese medicine extract, a preparation method thereof and application to preparation of gastric cancer drugs. The traditional Chinese medicine extract is obtained by using Cynoglossum furcatum, Aleuritopteris argentea, Decaisnea insignis and Heteropappus eligulatus through water extraction, alcohol extraction, dialysis and column purification, is used as an active component of a medicine composition pharmaceutically receiving additive and is applied to the preparation of drugs for treating gastric cancers. Effective components of raw materials such as Cynoglossum furcatum are extracted and are used for preparing the drugs for treating gastric cancers, and according to anticancer experimental researches on in-vitro various human gastric tumor cells and in-vivo tumor animal models, the traditional Chinese medicine extract is found to have a better effect of inhibiting in-vivo and in-vitro tumor cells and have a very remarkable effect of treating gastric cancers.

Description

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Claims

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Application Information

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Owner 杨美娟
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