Traditional Chinese medicine extract, preparation method thereof and application to preparation of gastric cancer drug
A technology of extracts and traditional Chinese medicines, applied in the directions of drug combinations, pharmaceutical formulations, medical raw materials derived from ferns/filamentous plants, etc. inhibitory effect
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[0021] Example 1
[0022] The traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 30 parts of glaucoma, 30 parts of Tongjing grass, 15 parts of cat feces melon, and 28 parts of tongueless dog flower.
[0023] The preparation method of above-mentioned Chinese medicine extract, concrete preparation steps are as follows:
[0024] (1) Washing, drying, pulverizing and sieving each crude drug respectively, placing it in an extraction tank, adding distilled water, the mass ratio of material to liquid is 1:10, and extracting under pressure for 4 times at 100 ° C, and the pressure is controlled at 8 Atmospheric pressure, extract 3h each time, and combine the extracts to obtain extract A;
[0025] (2) soaking the extract A in 12 times ethanol and refluxing for 3 times, filtering and concentrating to a relative density of 1.10-1.15, and freeze-drying to obtain the extract C;
[0026] (3) Dissolve the above-mentioned extract C in an appropr
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[0028] Example 2
[0029] The traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 35 parts of glaucoma, 25 parts of Tongjingcao, 20 parts of cat feces melon, and 26 parts of tongueless dog flower.
[0030] The preparation method of above-mentioned Chinese medicine extract, concrete preparation steps are as follows:
[0031] (1) Washing, drying, pulverizing and sieving each crude drug respectively, placing it in an extraction tank, adding distilled water, the mass ratio of material to liquid is 1:11, and extracting under pressure for 4 times at 100 ° C, the pressure is controlled at 8 Atmospheric pressure, extract 3h each time, and combine the extracts to obtain extract A;
[0032] (2) soaking the extract A in 14 times of ethanol and refluxing for 4 times, filtering and concentrating to a relative density of 1.10-1.15, and freeze-drying to obtain the extract C;
[0033] (3) Dissolve the above-mentioned extract C in an appropriate
Example Embodiment
[0035] Example 3
[0036] The traditional Chinese medicine extract is prepared from the following raw materials in parts by weight: 40 parts of glaucoma, 20 parts of Tongjing grass, 25 parts of cat feces melon, and 24 parts of tongueless dog flower.
[0037] The preparation method of above-mentioned Chinese medicine extract, concrete preparation steps are as follows:
[0038] (1) Washing, drying, pulverizing and sieving each crude drug respectively, placing it in an extraction tank, adding distilled water, the mass ratio of material to liquid is 1:12, extracting under pressure for 4 times at 100 ° C, and the pressure is controlled at 8 Atmospheric pressure, extract 3h each time, and combine the extracts to obtain extract A;
[0039] (2) soak the extract A in 15 times of ethanol and reflux for 5 times, filter and concentrate to a relative density of 1.10-1.15, and freeze-dry to obtain the extract C;
[0040] (3) Dissolve the above-mentioned extract C in an appropriate amount of
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