Anti-freeze hand cream and preparation method of same

[0020] The preparation method of the plum blossom extract comprises: taking plum blossom petals with a water mass of less than 10%, soaking them in ethanol aqueous solution, refluxing extraction, and filtering to obtain the first filtrate; adding chitosan aqueous solution to the first filtrate, flocculating, and filtering to obtain the first filtrate the second filtrate; concentrating the second filtrate under reduced pressure to obtain a concentrated solution; passing the concentrated solution through a column and collecting the column liquid to obtain the plum blossom extract.

[0021] In a specific embodiment, the preparation method of plum blossom extract comprises:

[0022] (1) Take dried plum blossom petals as raw material, the water content of which is <10%, take 10-50 parts of dried plum blossom petals, add 1-1.5 times of 10-30% ethanol aqueous solution and soak for 1.5-3h;

[0023] (2) Reflux extraction for 2-4h, filter, and get the filtrate;

[0024] (3) Add 1% chit...

[0071] Step 1, the preparation process of plum blossom extract

[0072] (1) Add 0.5 times of 10% ethanol aqueous solution to soak 10 parts of plum blossom petals for 1.5 hours;

[0073] (2) Reflux extraction for 2h, filter, and get the filtrate;

[0074] (3) Add 1% chitosan aqueous solution of 1% of the filtrate amount, flocculate for 10min, filter, and get the filtrate;

[0075] (4) concentrated under reduced pressure at 75°C to a concentrated solution of 0.5 crude drug / ml;

[0076] (5)) pass through a resin column (a chromatographic column with a diameter of 1.5 cm), the sample loading speed is 0.5 ml / min, and the column liquid is collected to obtain the plum blossom extract.

[0077] Step 2, the preparation of the extraction of allantoin

[0078] Select sugar beet as the extraction source of allantoin, and extract allantoin, specifically comprising: adopting a subcritical water extraction process to extract the allantoin active component of sugar beet to obtain an allant...

[0090] Step 1, the preparation process of plum blossom extract

[0091] (1) 30 parts of plum blossom petals were soaked in 1 times 20% ethanol aqueous solution for 2 hours;

[0092] (2) Reflux extraction for 3h, filter, and get the filtrate;

[0093] (3) Add 1% chitosan aqueous solution with 3.5% filtrate amount, flocculate for 35min, filter, and get filtrate;

[0094] (4) concentrated under reduced pressure at 78°C to a concentrated solution of 0.5 crude drug / ml;

[0095] (5) Pass through a resin column (a chromatographic column with a diameter of 1.5 centimeters), the sample loading speed is 1 ml / min, and the column liquid is collected to obtain the plum blossom extract.

[0096] Step 2, the preparation of the extraction of allantoin

[0097] Select sugar beet as the extraction source of allantoin, and extract allantoin, specifically comprising: adopting a subcritical water extraction process to extract the allantoin active component of sugar beet to obtain an allantoin e...