Hemostatic Devices with Improved Properties and Methods of Making Same

Active Publication Date: 2019-06-27
CORE SCI CREATIONS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0011]In some embodiments, improved hemostatic devices provide and maintain effective hemostasis when applied to wounds or traumas. In these embodiments, improved hemostatic devices are effective in providing and maintaining hemostasis in several cases including moderate to severe bleeding.
[0012]In other embodiments, improved hemostatic devices provide a unique level of adherence and gel stability, even in massive bleeding scenarios. In such scenarios, improved hemostatic devices allow high efficiency bleeding control in non-compressional and/or non-tourniquetable injuries such as vascular breaches, heart traumas, lungs injuries, spleen trauma, uterus trauma, placenta trauma, head trauma, spine, skeleton

Problems solved by technology

While the absorbency of body fluids and the hemostatic action of currently available carboxylic-oxidized cellulose hemostats are adequate for applications where mild to moderate bleeding is encountered, they are not known to be effective for pr

Method used

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Example

[0025]The present disclosure is described in detail with reference to certain embodiments. Other embodiments may be used and / or other changes may be made to the embodiments without departing from the spirit or scope of the present disclosure. The illustrative embodiments described in the detailed description are not meant to be limiting of the subject matter presented herein.

Definitions

[0026]As used here, the following terms have the following definitions:

[0027]“Alkalization agent” refers to an alkali metal hydroxide or alkaline earth metal hydroxide that is used for activating the non-oxidized regenerated cellulose.

[0028]“Effective hemostasis” refers to the ability to control and / or abate capillary, venous, or arteriole bleeding within an effective time, as recognized by those skilled in the art of hemostasis. Further indications of effective hemostasis may be provided by governmental regulatory standards and the like.

[0029]“Hemodynamic gel” refers to a gel which can absorb platel

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Abstract

Hemostatic devices and methods of making same are disclosed. Disclosed hemostatic devices include biocompatible non-oxidized regenerated cellulose. The disclosed hemostatic devices are effective in providing and maintaining hemostasis in cases of moderate to severe bleeding caused by non-compressional and/or non-tourniquetable injuries, among other things. The disclosed methods enable manufacture of a bioabsorbable, biocompatible, biodegradable carboxymethyl cellulose having high stability and high adherence.

Description

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Claims

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Application Information

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Owner CORE SCI CREATIONS
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