The invention discloses a location method of a simulation base station based on an A interface signal, which belongs to the field of mobile communication. The method comprises steps of firstly collecting the A interface signal in a Global System for Mobile Communications (GSM) network, generating a calling detail record (CDR), adding the CDR to a signal database, performing an association analysis to information in the signal database, and obtaining a statistic analysis result; then unscrambling location area codes of the simulation base station in accordance with the statistic analysis result and obtaining lists of normal cells near the simulation base station; and finally locating a geographical position and distribution of the simulation base station according to the lists of normal cells near the simulation base station. According to relative signal data information in updating of positions of mobile communication users, the method evaluates the problems of the simulation base station in the mobile communication effectively in real time, cannot be affected by regions and other factors, enables operators to know mobile communication network conditions in time, and arranges reasonably people to perform network optimization.