Biocompatible dialysis fluids containing icodextrins
A technology of icodextrin and peritoneal dialysis, applied in dialysis systems, peritoneal dialysis, medical preparations containing active ingredients, etc., can solve problems such as pain and peritoneal cell cytotoxicity
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Embodiment 1
[0047] Composition of the glucose polymer chamber
[0048] Icodextrin (g / L) 100.0-220.0
[0049] Calcium chloride dihydrate (mEq / L) 5.0-10.0
[0050] Magnesium chloride hexahydrate (mEq / L) 0.5-2.0
[0051] HCl, for adjusting pH from 2.5 to 5.0
[0052] The composition of the buffer chamber
[0053] Sodium chloride (mEq / L) 50.0-150.0
[0054] Sodium Lactate (mEq / L) 50.0-120.0
[0055] Sodium bicarbonate and / or histidine, to adjust the pH to 8.0 to 9.0
Embodiment 2
[0057] Composition in the glucose polymer compartment (large compartment)
[0058] Icodextrin (g / L) 121
[0059] Sodium chloride (g / L) 4.22
[0060] Calcium chloride dihydrate (g / L) 0.40
[0061] Magnesium chloride hexahydrate (g / L) 0.08
[0062] Sodium Lactate (g / L) 3.50
[0063] pH about 5.0 to about 5.4
[0064] The composition of the buffer room (cabin)
[0065] Sodium chloride (g / L) 7.42
[0066] Sodium lactate (g / L) 6.15
[0067] Sodium bicarbonate (g / L) 0.58
[0068] pH about 8.2 to about 8.7
[0069] Icodextrin and Ionic Composition in Mixed Solutions
[0070] Icodextrin (g / dL) 4.0-10.0
[0071] Calcium (mEq / L) 0.5-4.0
[0072] Magnesium (mEq / L) 0.25-2.0
[0073] Sodium (mEq / L) 120.0-135.0
[0074] Chlorine (mEq / L) 90.0-110.0
[0075] Lactate (mEq / L) 30.0-45.0
[0076] Bicarbonate or Histidine (mM) NMT 5.0
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