2 results about "Bone resorption" patented technology

The present invention relates to the methods of treating periodontal disease and bone resorption in the maxilla or mandible comprising the inversion of the adjacent periosteum. The adjacent periosteum is inverted in an effort place the proper regenerative cells in the area of tissue loss in a mammal in need thereof with the goal of regenerating lost periodontium and alveolar bone.

The invention belongs to the field of biomedical materials and discloses application of miR-141 in the preparing of anti-osteoporosis and bone-resorption-inhibiting preparations. Experiments prove that the miR-141 inhibits the differentiation process of osteoclasts by regulating the expression of genes related to osteoclast differentiation. The miR-141 can inhibit bone mass loss and osteoporosis, so that the miR-141 can be used for preparing the various biomedical anti-osteoporosis and bone-resorption-inhibiting preparations.