The invention discloses cassia twig and poria cocos pills and a preparation method thereof. The cassia twig and poria cocos pills are prepared from, by weight, 190-210 parts of cassia twigs, 190-210 parts of poria cocos, 190-210 parts of cortex moutan, 190-210 parts of radix paeoniae rubra and 190-210 parts of peach kernels. The cassia twig and poria cocos pills have the effects of promoting blood circulation to remove blood stasis and relieving and eliminating lumps and can be used for treating symptoms of blood stasis retention in uterus, gestation threatened abortion, endless metrostaxis, uterine fibroid, endometriosis, ovarian cyst, annexitis and chronic pelvic inflammation; meanwhile, the cassia twig and poria cocos pills have the advantages of being reasonable in cost, small in toxic and side effects, convenient to take and short in curative effect; the cassia twig and poria cocos pills can be produced in a batched mode, are wide in appropriate people and have extremely high popularization value.