2 results about "Keratinocyte" patented technology

The invention discloses an oil-control pore-shrinking composition containing lactobionic acid. The oil-control pore-shrinking composition comprises the following components in percentage by weight: 0.0001-20% of lactobionic acid, 0.0001-30% of a flos spiranthis sativae extract, 0.0001-20% of nicotinamide and 0.0001-20% of carnitine. The oil-control pore-shrinking composition disclosed by the invention can intelligently identify aged keratinocytes, remove aged dead cells and promote the regeneration of the keratinocytes. The oil-control pore-shrinking composition can remove dirt in pores, helpthe proliferation of hyaluronic acid and collagen in a dermis layer, increase the water content of skin, visually shrink the pores and enable the whole skin to become compact and elastic. The flos spiranthis sativae extract can effectively shrink coarse pores, inhibit abnormal oil production of hair follicles and inhibit bacterial reproduction and prevent acnes. Moreover, the oil-control pore-shrinking composition is mild and non-irritant, can serve as an oil-control pore-shrinking active component and is applied to various cosmetics.

The serum-free culture of normal human epithelial stem cells is of paramount importance for the in vitro formation of cloned human tissues by means of cell therapy. Several growth promoting agents are disclosed for use in a serum-free culture medium of normal human keratinocytes. Lithium ions, dibutryl-cyclic adenosine monophosphate, and prostaglandin E1 have been found effective as growth enhancing agents to be added singly or in combination, when used in combination with insulin-like growth factor-1. Lithium ions and prostaglandin E1 are disclosed as independent growth enhancing factors, that replace epidermal growth factor as a necessary growth factor required for keratinocyte clonal growth.