The invention discloses a stepless rotation quick release structure of a root canal therapy handpiece. The comprises a handpiece and a handle, the handpiece is rotatably and detachably connected to the handle, one end of the handpiece is connected to a quick release connector, a connector socket is arranged at the end, away from the handpiece, of the quick release connector and rotationally connected to the quick release connector, a C-shaped groove is formed in one end of the quick release connector, a positioning pin is arranged at one end of the connector socket, the quick release connectorand the outside of the connector socket are sleeved with a connector outer sleeve, an annular groove is formed in the outer side of the quick release connector, and a detachable sealing ring is arranged in the annular groove. The handpiece can rotate relative to the handle through matching of the quick release connector and the connector socket, the quick release structure is simple in structureand convenient to use, the rotating angle can be adjusted at will, the working efficiency is improved, pain of a patient in the treatment process is relieved, the comfort degree is improved, and operation is convenient and sanitary; and the quick release connector and the connector socket are fixed by the connector outer sleeve, so that a rotating structure formed by the quick release connector and the connector socket is prevented from loosening when the handpiece is inserted and pulled relative to the handle.