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In genetics, a promoter is a region of DNA that leads to initiation of transcription of a particular gene. Promoters are located near the transcription start sites of genes, upstream on the DNA (towards the 5' region of the sense strand). Promoters can be about 100–1000 base pairs long.

Regulation of transcription through ctcf loop anchors

PendingUS20200149039A1Facilitate oncogenic expression of geneHigh expressionCompound screeningApoptosis detectionDiseaseBinding site

Disclosed are methods of altering expression of a gene with a promoter region CTCF binding site. Also disclosed are compositions and methods useful for treating a disease or condition involving over-expression or under-expression of a gene with a promoter region CTCF binding site. Further disclosed are cells and non-human animals with modified a promoter region CTCF binding site, as well as methods for screening for compounds that can modify the expression of a gene with a promoter region CTCF binding site.

Regulation of transcription through ctcf loop anchors

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Owner:WHITEHEAD INST FOR BIOMEDICAL RES

1 results about "Promoter" patented technology

Regulation of transcription through ctcf loop anchors

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