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1 results about "Pulmonary disease" patented technology

Vaccine composition, preparation method and application thereof

ActiveCN104324370AAntigen purification method is simplePreserve immune active ingredientsAntibacterial agentsBacterial antigen ingredientsActive componentPorcine lung
The invention provides a preparation method for preparing a vaccine composition containing mycoplasma hyopneumoniae antigen. The preparation method comprises following steps: (1) cultivating mycoplasma hyopneumoniae and performing inactivation; (2) treating the mycoplasma hyopneumoniae inactivated in the step (1) with a nonionic surfactant; and (3) separating an antigenic component which is insoluble in the nonionic surfactant after the treatment with the nonionic surfactant and adding an adjuvant. The invention also provides the vaccine composition containing the mycoplasma hyopneumoniae antigen. In the vaccine composition, vaccine inhibiting components are removed and immune active components are maximumly retained. When the vaccine composition works with a porcine circovirus antigen, an inhibiting effect on the porcine circovirus antigen by the vaccine composition does not exist so that a better protective effect on porcine lung lesions is achieved.
Owner:PULIKE BIOLOGICAL ENG INC

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