2 results about "Bone Injury" patented technology

The invention relates to an oral cavity defect repair membrane and a preparation method thereof, in particular to an acellular matrix material and preparation thereof, and the application in the repair of oral cavity defect. The preparation comprises: (1) taking the porcine small intestine jejunum segment, cleaning, radial cutting, removing the mucosa layer, sarcolemma layer and serosa layer, andobtaining the porcine small intestine submucosa tissue membrane; (2) soaking the tissue membrane of the porcine small intestine submucosa obtained in the step (1) in peroxyacetic acid solution or sodium hydroxide solution, and take out and cleaning to obtain an acellular matrix of the porcine small intestine submucosa tissue; (3) soaking the porcine small intestinal submucosa tissue obtained in the step (2) with a dopamine solution, sterilize, and obtaining an acellular matrix material. The invention can avoid the loss of cell growth factor in the tissue membrane of the porcine small intestinesubmucosa, ensure the the obtained acellular matrix material has better tissue micropore structure and mechanical properties, and can meet the needs of oral bone injury repair; low immunogenicity andgood safety.