31results about "Aerosol delivery" patented technology

The invention belongs to the field of medicine and personal care, and particularly relates to propolis-aloe bacteriostatic gel and a preparation method thereof. The propolis-aloe bacteriostatic gel isprepared from the following raw materials in percentage by mass: 8-12% of golden cypress, 8-10% of fructus cnidii, 6-11% of stemona, 9-12% of fructus kochiae, 7-9% of divaricate saposhnikovia roots,4-8% of seaweeds, 3-6% of aloes, 0.5-0.8% of propolis, 1-1.4% of chlorhexidine acetate, 0.8-1.2% of carbomer 940, 0.08-0.11% of methylparaben, 0.09-0.12% of triethanolamine, 0.9-2.1% of ethanol and 36-40% of purified water. The propolis-aloe bacteriostatic gel is propolis-aloe gel prepared through the compound compatibility of the propolis and the aloes, through the synergistic effect of the propolis and the aloes, the effects of inhibiting the growth of bacteria, promoting wound healing, diminishing inflammation, realizing sterilization, realizing moistening and nourishing, replenishing water, removing acne, removing eczema and realizing spot-fading can be effectively achieved, and especially, the bacteriostatic effect on escherichia coli, staphylococcus aureus, hemolytic streptococcus and the like is achieved.

The invention belongs to the technical field of medicaments and provides a medicinal composition which separately adopts difluorochloromethane without environmental destruction as a propellant. The medicinal composition not only substitutes dichlorodifluoromethane commonly called Freon 12 with environmental destruction which is often used in pharmaceutical production, but also avoids the problems of the increased cost and complicated processing technology brought by mixing various propellants. Due the adoption of the propellant for proportioning, the aerosol composition has the advantages of controllable pressure in a wide range, simple production technology, easy operation and capacity of completely meeting the requirement on the dichlorodifluoromethane substitute.

The present invention provides a rheumatism plaster, a thread-gluing breathable bag for packing rheumatism plaster and a production method thereof. The rheumatism plaster includes the following raw materials such as dried pinellia tuber, dried bile arisaema, dried szechuan aconite, dried kusezoff monkshood root, dried nux vomica, sesame oil and yellow lead. The rheumatism plaster is obtained through the following method: a required amount of sesame oil is boiled; then a required amount of dried pinellia tuber, dried bile arisaema, dried szechuan aconite, dried kusezoff monkshood root and dried nux vomica are mixed, poured into boiling sesame oil and fried with mild fire until the drug turns black and carbonized; herb residues are removed after fire is extinguished and a required amount of yellow lead is poured and evenly mixed after the sesame oil cools without boiling. The present invention adopts high-temperature sesame oil to make decoction of the five drugs, so that the toxicity disappears without decreasing the pharmacodynamical effect. The pharmacodynamical ingredients can be fully fried out; in addition, the quality of sesame oil is sticky, the sesame oil gradually dilutes in normal temperature of human body, the pharmacodynamical effect gradually releases and the plaster does not infiltrates the gauze and attach on the skin, so that the present invention achieves the aim of curing rheumatism without allergy. Besides, the present invention also has simple structure and convenient use.

The invention relates to the preparation technology of a new integrative formulation of siwu decoction and a production method thereof. The siwu decoction comprises the following raw materials in part by weight: 15 parts of rehmanniae vaporata, 15 parts of Chinese angelica, 10 parts of white paeony root and 8 parts of szechuan lovage rhizome. The production process comprises the following steps of: alcohol/water extracting, ultrasonic crushing extracting, microwave extracting, decocting and concentrating, supersonic spray drying, high-pressure emulsification homogenizing, nanometer grinding, nanometer particle preparation and the like. The preparation technology and the production method have the advantages of multi-synergetic effect, multi-targeting effect and the like of nanometer traditional Chinese medicines. By the large-scale industrial production, the production cost can be reduced substantially, the quality of products can be improved, and the targeting and slow controlled release properties of medicaments are high; and a prepared membrane agent also can be applied to the skin of human bodies for treatment by transdermal absorption.

The invention relates to a hot massaging ointment capable of promoting blood circulation, removing blood stasis, dredging collaterals and relieving pain. The hot massaging ointment is prepared from the following 12 traditional Chinese medicines: a rue extract, an atropa belladonna fluid extract, frankincense, myrrh, radix linderae, rhizoma chuanxiong, radix curcumae, methyl salicylate, menthol, cinnamon oil, clove oil and camphor. Besides, the invention fuehrer relates to a preparation method of the hot massaging ointment. The preparation method mainly comprises the following steps: (1) preparing a traditional Chinese medicine extraction liquid; (2) preparing an oil phase; (3) preparing a water phase; and (4) combining the phases. The hot massaging ointment is relatively suitable for treating chronic soft tissue injury. The preparation method of the hot massaging ointment has the characteristics of strong process operability, good product reproducibility and high product yield; furthermore, the prepared hot massaging ointment has the characteristics that emulsion particle diameters are relatively small and are uniformly distributed, the transdermal absorption ratio is relatively high, and the pharmaceutical effect can be adequately developed.

The present invention providing a Chinese medicine ointment, particularly the one for curing herpes zoster and the preparation thereof, is directed to a drug combination of antibiotic and antiviral drug with the following disadvantages: a slow effect, an easy entry to the outbreak period, a long treatment time, a high cost of treatment and the like. The ointment with hedgehog skin and sesame oil as raw materials has properties in a simple prescription and production, a low cost, healing fast and a high cure rate without toxic and side effect.

The invention discloses a preparation method of herba dendrobium devonianum paste. The preparation method comprises the following steps: (1) selecting fresh herba dendrobium devonianum, washing the fresh herba dendrobium devonianum to be clean, peeling the fresh herba dendrobium devonianum, and cutting the peeled fresh herba dendrobium devonianum into segments; (2) selecting high-quality fructus ziziphi jujubae, washing the high-quality fructus ziziphi jujubae to be clean, and removing the stones of the washed high-quality fructus ziziphi jujubae; (3) adding the fresh herba dendrobium devonianum and fructus ziziphi jujubae into a juicer at the weight ratio of 2 to 1, and adding 25-35-fold amount of water into the juicer; (4) carrying out juicing for 1-3 min; (5) carrying out filtering; (6) heating the filtered liquid under moderate heat till the filtered liquid reaches the boiling state; (7) boiling the liquid under gentle heat for 15-25 min, thus concentrating the liquid to form paste; and (8) placing the paste till the paste reaches the cool state, packaging the paste into a bottle, and carrying out sealed storage. According to the preparation method, the juicing method is adopted, herba dendrobium devonianum and fructus ziziphi jujubae are juiced after being mixed, so that the palatability of the herba dendrobium devonianum paste is increased, meanwhile, the preparation time and cost of the herba dendrobium devonianum paste are also reduced, after the two medicine-food homologous materials, namely, herba dendrobium devonianum and fructus ziziphi jujubae are adopted for preparing the paste, the obvious effect of enhancing the immunity is achieved.

The invention provides a traditional Chinese medicinal algae facial mask. The facial mask comprises the following components: Chinese angelica, hemlock parsley, white peony root, raw rehmannia root, red-rooted salvia root, scutellaria baicalensis, safflower, bitter orange, sweet wormwood, szechwan Chinaberry fruit, areca-nut, golden cypress, angelica root and algae. The traditional Chinese medicinal algae facial mask is good in clinical curative effect for treating hormone dependence facial dermatitis, and is high in cure rate. The clinical materials in the traditional Chinese medicinal algae facial mask can be obtained conveniently and easily, the treatment effect is satisfactory, the method is simple and practical, and the medical treatment cost is low, so that the facial mask is suitable for treatment in various levels of hospitals, in particular primary hospitals.

The invention provides a transdermal absorption pharmaceutical composition containing testosterone. The pharmaceutical composition is composed of male sex hormone used as an active component and one or a plurality of pharmaceutical adjuvants pharmaceutically applicable to a transdermal delivery system. The pharmaceutic adjuvants pharmaceutically applicable to the transdermal delivery system comprise a penetration enhancer and one or a plurality of alcohols which is in a liquid state under normal temperature. The male sex hormone is testosterone, dihydrotestosterone, methyltestosterone, testosterone propionate and testosterone undecanoate, and preferably, testosterone and dihydrotestosterone.

The present invention relates to a pharmaceutical aerosol composition comprising tacrolimus as the active ingredient and the use of the composition in the treatment of inflammatory dermal diseases. The aerosol composition comprise a propellant mixture and further a pharmaceutically acceptable hydrophobic carrier solubilized or suspended in said propellant mixture.

The invention discloses a thermo-sensitive collagen compound anti-inflammatory gel spray for treating psoriasis and a preparation method thereof. The thermo-sensitive collagen compound anti-inflammatory gel spray comprises the following raw materials in part by weight: 45-65 parts of thermo-sensitive collagen-based antibacterial and anti-inflammatory gel, 15-20 parts of hemostatic drug, 12-18 parts of dandelion, 3-5 parts of forsythia suspensa, 2-4 parts of radix salviae miltiorrhizae, 1-3 parts of ligusticum wallichii, 4-8 parts of tuberculate speranskia herbs, 8-12 parts of glycerinum, 2-3 parts of rosemary essential oil, 1.5-3.5 parts of glycerol monolaurate and 10-20 parts of water. The thermo-sensitive collagen compound anti-inflammatory gel spray for treating the psoriasis and the preparation method thereof disclosed by the invention have the benefits that according to research results on skin deficiency of collagens in a psoriasis patient, an antibacterial and anti-inflammatoryingredient is added based on the original efficacy of the thermo-sensitive collagen-based compound hemostatic gel; the treatment of both symptoms and root causes of the psoriasis is realized by adopting a method of direct collagen supplement and combination of sterilization and anti-inflammation with dietary supplement for a psoriasis diseased area. The thermo-sensitive collagen compound anti-inflammatory gel spray adopts a spray manner, is convenient to use and has very good application prospect.

The invention relates to hypotensive double plasters, belonging to the traditional Chinese medicine field. The foot plaster of the invention comprises the following raw materials by weight: 15-20kg of Achyranthis bidentata, 15-20kg of Gastrodia elata, 15-20kg of Glandularstalk St.Paulswort herb, 0.017-0.1kg of borneol, 10-15kg of evodia, 15-20kg of Apocynum venetum L and 15-20kg of gentian; and the umbilical plaster of the invention comprises the following raw materials by weight: 15-20kg of Radix Rehmannia Glutinosa, 15-18kg of jujube kernel, 15-20kg of Chinese wolfberry, 15-18kg of eucommia bark, 15-20kg of plantain seed, 15-18kg of salted aconite root and 7-10kg of cinnamon. The hypotensive double plasters adopt pure Chinese medicinal herbs and have the functions of enriching yin and nourishing kidney, and calming liver and checking exuberance of yang. The medicine is permeated and absorbed through skin mesenchyme intercellular space, follicle walls, sweat glands and sebaceous glands to stimulate the exteroceptor and affect and adjust blood pressure, has no toxicity, stimulation and side effect, and is safe and effective.

The invention relates to preparation of a natural active matter procyanidine multiple emulsion hydrogel, which comprises the following steps: heating corn oil, acetylated monoglyceride, polyethylene glycol 30-dipolyhydroxystearate and a deionized water solution containing procyanidine in a water bath at 65 DEG C, magnetically stirring for 15 minutes at the rotating speed of 600 rpm to prepare primary emulsion, slowly dropwise adding the primary emulsion into a deionized water solution containing Tween 80, heating in a water bath at the temperature of 50 DEG C, and magnetically stirring for 10 minutes at the rotating speed of 400 rpm to prepare the procyanidine multiple emulsion. The prepared procyanidine multiple emulsion and 5% chitosan hydrogel are stirred for 5 min at the mass ratio of 1: 1 and the speed of 100 rpm and fully mixed, then the mixture is dropwise added into a 2.5% sodium tripolyphosphate cross-linking agent for cross-linking, and cross-linking is conducted for 20 min, and the procyanidine multiple emulsion hydrogel ball can be prepared.

The invention provides an application of a mulberry-ginger cold injection to preparing of an atomization preparation and a rectal administration preparation and a preparing method of the mulberry-ginger cold injection. The mulberry-ginger cold injection comprises mulberry-ginger extract, solubilizer, cosolvent and pH adjusting agent, and the mulberry-ginger cold injection is prepared through corresponding technology processes. The total effective rate is 95% or above when the mulberry-ginger cold injection is applied to atomization-treating of upper respiratory infection or rectal-administration-treating of upper respiratory infection.

The invention discloses hui medicine unguent. According to the hui medicine unguent, radix stellariae, Chinese mahonia root, radix polygalae, liquorice root, rhizoma dioscoreae nipponicae, silybum marianum seed and semen sophorae alopecuroide extracting solutions are concentrated as traditional Chinese medicine extract; nanoscale extracts of fructus lysii, folium mori, rhizoma seu radix notopterygii, herba rhodiolae and stone-like omphalia are utilized as traditional Chinese medicine powder; then meglumine adenosine cyclophosphate with a hemostasis effect is utilized as a hemostatic agent, andthe hui medicine unguent is prepared by concentrated after mixed ultrasonic dispersion; a mass fraction proportion of the traditional Chinese medicine extracts to the traditional Chinese medicine powder and the meglumine adenosine cyclophosphate is 100 to 48 to 0.1. The invention further discloses application of the unguent in unguent patch containing a graphite novel fiber layer.

The invention discloses atomized liquid inhaled by people with rhinitis and a preparation method thereof. The atomized liquid inhaled by people with rhinitis is mainly prepared from, by weight, 15-20 parts of flos magnoliae liliflorae, and 10-15 parts of fresh ginger. After being inhaled through the nasal cavity, the inhaled atomized liquid for people with rhinitis disclosed by the invention has an obvious treatment effect on chronic rhinitis, allergic rhinitis and nasal polyp, and does not have any side effect.

The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine healing ointment. The ointment comprises the components of 15-30 parts of musk, 20-30 parts of pseudo-ginseng, 10-20 parts of small-leaf bonesetting, 4-6 parts of glycerol and 10-20 parts of medical vaseline. The purpose of this invention is to provide the convenient traditional Chinese medicine healing ointment with strong penetration.

The invention discloses hemorrhoid-eliminating and crack-healing cream and a preparation method thereof. The hemorrhoid-eliminating and crack-healing cream comprises a formula I, a formula II and a formula III, the formula I comprises the following raw materials by weight: 100g of rumex japonicus, 80g of rhizoma picrorhizae, 50g of radix notoginseng, 60g of flos sophorae immaturus, 40g of semen momordicae, 60g of radix sophorae flavescentis, 60g of carbonized sanguisorba root, 0.5 kg of sesame oil and 300g of beewax; the formula II comprises the following raw materials by weight: 25g of borneol, 25g of verdigris, 25g of alum, 25g of anhydrous sodium sulphate, 25g of minium and 25g of mentholum. The traditional Chinese medicine overcomes many defects, is rigorous in formula, convenient to prepare and exact in curative effect, and has a good treatment effect on internal hemorrhoids, external hemorrhoids, mixed hemorrhoids, internal hemorrhoid hemafecia, red, swollen and hot pain of external hemorrhoids, hemorrhoid prolapse or rectocele, hemorrhoid abscess and ulceration, anal fissure, internal hemorrhoids flowing dirt and the like.

A pharmaceutical composition for treating acne and having a cosmetic effect, belonging to the technical field of medicine or cosmetics, the composition includes traditional Chinese medicines such as rhubarb, salvia miltiorrhiza, angelica dahurica, astragalus, citron, red stone fat, licorice, borneol, and semen japonicus, It is very effective for treating acne, and has the advantages of low cost, short course of treatment, high cure rate and low recurrence rate.