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79results about "Hydroxy compound active ingredients" patented technology

Composition containing 3-methyl-1-phenyl-2-pyrazoline-5-ketone

The invention relates to a composition comprising 3-methyl-1-phenyl-2-pyrazoline-5-ketone and borneol, and application thereof in preparing a medicine for treating cerebrovascular diseases, particularly ischemic cerebrovascular diseases. The typical ischemic cerebrovascular disease is cerebral infarction.
Owner:JIANGSU SIMCERE PHARMACEUTICAL R & D CO LTD

Propofol injection and its preparing method

A propofol injection with high safety and stability is prepared from propofol, the oil for injection, emulsifier, isotonic regulator and the water for injection. Its preparing process is also disclosed.
Owner:SHANGHAI INST OF PHARMA IND

Ivermectin suspending agent, preparation method and application thereof

InactiveCN101862294AEasy to takeAccurate doseHydroxy compound active ingredientsAntiparasitic agentsMedicineBiocompatibility Testing
The invention discloses an ivermectin suspending agent, a preparation method and application thereof. Each liter of the ivermectin suspending agent is prepared from 2 to 100g of ivermectin raw material medicament, 200 to 550g of oil, 30 to 200g of emulsifier and a proper amount of water; and an auxiliary agent can be added when necessary. The ivermectin suspending agent prepared by the preparation method has the characteristics of high stability and biocompatibility and remarkable sustained-release effect, can be applied to the preparation of an ivermectin sustained-release injection, fills a domestic technology gap, and develops a new technical field for the application of ivermectin. The preparation method for the suspending agent has the characteristics of simplicity, easy implementation and low manufacturing cost.
Owner:ZHEJIANG BORNSUN MEDICINE CO LTD

Medicinal composition and its use in preparing medicine for treating or preventing cardio-cerebral vascular diseases

The present invention provides magnolol, magnolol salt and their medicine composition, and their application in treating and preventing cardiac and cerebral vascular diseases. The medicine composition has effect in treating and preventing cardiac and cerebral vascular diseases far higher than that of magnolol and / or magnolol salt.
Owner:SHANDONG GREENERY NATURAL MEDICINE RES & DEV

Synergistic effects of nuclear transcription factor NF-κB inhibitors and anti-neoplastic agents

InactiveUS7105576B2Augments paclitaxel-induced apoptosisGood treatment effectBiocideHydroxy compound active ingredientsPaclitaxelFactor ii
The present invention provides methods of inhibiting metastasis of a tumor and methods of treating a tumor using a combination of an inhibitor of the activation of nuclear factor NF-κB and a cancer chemotherapeutic agent. In one embodiment of the present invention, combination of curcumin and paclitaxel (taxol) can be used to treat and inhibit metastasis of breast tumor.
Owner:RES DEVMENT FOUND

Capsules capable of activating blood and stopping pains and preparation method of capsules

InactiveCN106074658AIncreased yield of ferulic acidSimple structureHeavy metal active ingredientsHydroxy compound active ingredientsAlcohol contentGround beetle
The invention provides a preparation method of capsules capable of activating blood and stopping pains. The preparation method comprises the following steps: taking six types of medicinal materials including 22g of Chinese angelica, 44g of radix notoginseng, 44g of vinegar processed frankincense, 11g of borneol, 111g of ground beetles and 67g of calcined pyrite; adding water with the weight which is 10 times as much as that of the medicinal materials; immersing for 0.5h and decocting for 1 hour; filtering and adding water with the weight which is 8 times as much as that of the medicinal materials into medicine residues; decocting for 1 hour and filtering medicine liquid; combining decocted liquid of the two times and concentrating until the relative density is 1.05 at 60 DEG C; adding ethanol until the volume percent of alcohol content reaches 75 percent; stirring, standing and filtering; concentrating filtrate until the relative density is 1.25 at 65 DEG C; recycling the ethanol to obtain a concentrated solution; carrying out super-critical extraction to obtain super-critical extract; continually concentrating and drying the concentrated solution; granulating and filling the capsules to obtain the capsules capable of activating blood and stopping pains. By adopting specific concentration and drying equipment, the prepared capsules capable of activating blood and stopping pains have high content of ferulic acid and can be applied to preparation of medicines for inhibiting Vero-E6 cell proliferation of African green monkey kidneys.
Owner:南京多宝生物科技有限公司

Method for establishing animal model for senile dementia, special liquid medicine and dosing device

InactiveCN103284980ATypical behaviorTypical pathological symptomsHydroxy compound active ingredientsMedical devicesSterile environmentSenile dementia
The invention relates to a method for establishing an animal model for senile dementia, a special liquid medicine and a dosing device, and belongs to the technical field of neurosciences. The method comprises the following steps: obtaining positioning coordinates of paraceles according to brain atlases or/and magnetic resonance image data of an experimental animal; respectively burying a conduit of the dosing device in left and right paraceles of the animal, and injecting the special liquid medicine to the paraceles at a constant speed in 14-16 minutes under a sterile environment within 2-3 weeks, wherein the liquid medicine amount is 100-250 ml methanol per day; alternately dosing the left and right paraceles, wherein the dosing frequency is 18-30 hours at an interval; and continuously dosing for 2-10 months to obtain a non-human primate animal model for senile dementia. With the adoption of a novel dosing mode: dosing to the paraceles at the constant speed, medicine can circulate to whole brain through the cerebrospinal fluid to exert the toxic effect, so that peripheral damage by the medicine is avoided. The AD model is established by injecting methanol or formaldehyde to the paraceles, so that behaviors and pathological symptoms are typical, the basic physiological status is good and the individual difference is relatively smaller.
Owner:KUNMING INST OF ZOOLOGY CHINESE ACAD OF SCI

Dispersible tablet for clearing heat, relieving sore-throat, detoxifying and relieving pain, and preparation method for same

The invention discloses a dispersible tablet for clearing heat, relieving sore-throat, detoxifying and relieving pain, and a preparation method for the same. The dispersible tablet contains the following ingredients in parts by weight: 350 parts of honeysuckle, 200 parts of blackberry lily, 250 parts of arrowshaped tinospora root, 250 parts of platycodon grandiflorum, 250 parts of radix scrophulariae, 250 parts of radix ophiopogonis, 1 part of calculus bovis, and 0.5 parts of borneol. According to the dispersible tablet and the preparation method for the same disclosed by the invention, the medicines except calculus bovis and borneol are prepared into dry paste powder, the dry paste powder is 51.8 parts by weight, and the dry paste powder comprises the raw materials and auxiliary materials in the following parts by weight: 10 parts of sodium carboxymethyl starch, 13.2 parts of polyvinylpolypyrrolidone, 24 parts of microcrystalline cellulose, 0.5 parts of magnesium stearate, 0.5 parts of aerosil, and 50 parts of ethanol. The dispersible tablet disclosed by the invention is a pure traditional Chinese medicine composition oral solid preparation, and prepared according to the compatible principle of traditional Chinese medicine prescriptions; and the dispersible tablet has the effects of clearing heat, relieving sore-throat, detoxifying and relieving pain.
Owner:XIAN TAKOMED PHARMA TECH

Multipurpose gas detection and purification device

PendingCN109059117AAvoid discomfortConcentration controllableMechanical apparatusAir-treating devicesHigh concentrationToxic gas
The invention discloses a multipurpose gas detection and purification device. The device comprises a power supply assembly, an induction control assembly, an execution assembly and an air purificationassembly; the induction control assembly comprises a single-chip microcomputer, a gas-sensitive sensor and a gas concentration sensor; the gas-sensitive sensor is used for detecting peculiar smell, toxic gas and concentration information thereof; the gas concentration sensor is used for detecting the concentration information of traditional Chinese medicine gas after the action of a fan; the execution assembly comprises a high-temperature traditional Chinese medicine evaporator, the fan and a display screen, wherein the high-temperature traditional Chinese medicine evaporator, the fan and thedisplay screen are correspondingly with the single-chip microcomputer, and the high-temperature traditional Chinese medicine evaporator is placed in front of the fan and used for evaporating the traditional Chinese medicine gas; and the single-chip microcomputer controls the fan to work discontinuously according to the concentration information of the traditional Chinese medicine gas, and controls the traditional Chinese medicine evaporator to work or not in high temperature according to the concentration information of the toxic gas. According to the device, the toxic gas in closed space canbe eliminated, the traditional Chinese medicine gas is used for discontinuously neutralizing an odor, the concentration of the traditional Chinese medicine gas is controllable, and therefore discomfort caused by exceedingly-high concentration of the traditional Chinese medicine gas is avoided.
Owner:GUANGDONG IND TECHN COLLEGE

Ointment used for warming and moxibustion, and preparation method thereof

InactiveCN108524837AHydroxy compound active ingredientsAntipyreticLicorice root extractGinger Rhizome
The invention discloses an ointment used for warming and moxibustion, and a preparation method thereof. The raw materials comprise soybean extracted product, vitamin C, Ligusticum wallichii extractedproduct, frankincense resin extracted product, red sage root extracted product, Chinese angelica root extracted product, rhizoma sparganii extracted product, safflower extracted product, ginger root oil, myrrh oil, herba centellae extracted product, Rhizoma Polygontum Cuspidatum extracted product, Radix Scutellariae extracted product, tea extracted product, glycyrrhiza glabra root extracted product, Chamomilla Recutita flower extracted product, and rosemary leaf extracted product. According to the preparation method, thermotherapy effect of traditional Chinese medicines including Ligusticum wallichii, frankincense, Chinese angelica, safflower, ginger, herba centellae, Rhizoma Polygontum Cuspidatum, and Radix Scutellariae is adopted to realize moisture dispelling and perspiration, satisfying treatment requirements of discomfort symptoms caused by dampness and coldness and bone disease, the ointment used for warming and moxibustion can be used for health care smearing in daily life, andachieving disease prevention, qi and blood circulation improvement, and life prolonging effect.
Owner:湖南金领伟业职业技能鉴定有限公司

Arthralgia and myalgia patch and manufacturing method thereof

InactiveCN108578588APlay a therapeutic roleInhibit bone hyperplasiaHydroxy compound active ingredientsAntipyreticMonkshoodsGastrodia
The invention discloses an arthralgia and myalgia patch and a manufacturing method thereof. An ointment comprises, by weight, 290-310 parts of Chinese clematis roots, 115-135 parts of Chinese angelicaroots, 115-135 parts of fortune's drynaria rhizomes, 25-35 parts of incised notopterygium rhizomes and roots, 25-35 parts of doubleteeth pubescent angelica roots,55-56 parts of chuanxiong rhizomes, 25-35 parts of Himalayan teasel roots, 25-35 parts of medicinal cyathula roots, 25-35 parts of tall gastrodia rhizomes, 5-15 parts of pangolin scales, 25-35 parts of slenderstyle acanthopanax roots andbarks, 5-15 parts of dragon's blood, 25-35 parts of Solamum melongena, 15-25 parts of prepared Chinese monkshood roots, 15-25 parts of prepared kusnezoff monkshood roots, 25-35 parts of fresh reddishjackinthepulpit rhizomes, 25-35 parts of fresh ternate pinellia rhizomes, 25-35 parts of white mulberry barks, 25-35 parts of dahuria gentian roots, 25-35 parts of olibanum, 90-110 parts of borneol,25-35 parts of camphor and 10 parts of wild mint oil. A formula of the paste can effectively control pain, restrain hyperostosis and treat bone diseases. According to the manufacturing method of the paste, 90% of effective components are extracted through ethyl alcohol, effective components in medicinal materials can be efficiently extracted through an extracting process, the utilization ratio ofthe medicinal materials is increased, and cost is reduced.
Owner:安吉濮济生堂中医门诊有限公司
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