98results about "Unknown materials" patented technology

Dietary supplements and methods for management and control of body weight comprising at least one liver protecting agent and at least one mushroom in the form of powder, extract, or combinations thereof.

A Chinese medicine in the form of pill, capsule, or decoction for treating liver cancer, lung cancer, blood cancer, stomach cancer and cardia cancer is prepared from Chinese-medicinal materials including green vitriol, toad, telini fly, carmbola root, etc.

A method for preparing a treatment composition for treatment of osteoarthritis including un-cultured stromal vascular fraction cells from adipose tissue includes direct aspiration of material of a centrifugally-formed pellet phase including stromal vascular fraction cells from enzymatically-digested adipose tissue from an internal containment volume of a portable apparatus through an aspiration tube inserted into the pellet phase and into a fluid receptacle located outside of the internal containment volume. The treatment composition may be administered into or in the vicinity of a patient's joint to be treated for osteoarthritis.

The invention relates to methods of treating melanoma using a herpes simplex virus in combination with an immune checkpoint inhibitor.

An insect repellent composition containing citronella oil, D-limonene, 2 or more synergists, and 3 or more essential oils as the active ingredients. The preferred essential oils are geranium oil, rosemary oil and peppermint oil, but other essential oils may be used. In the preferred embodiment the synergists are aldehyde C-14 and aldehyde C-18. As desired, vanillin may be used as a stabilizer, and fragrances, fragrance enhancers and surfactants may be utilized.

A bifidobacteria colostrum-soluble soft capsule and a preparation method thereof. The invention relates to a bifidobacterium colon-soluble soft capsule and a preparation method thereof. The soft capsule includes two parts, a content and a rubber skin, and the shell of the soft capsule is processed to make it colon-soluble. The content of the soft capsule is a stable suspension prepared by mixing and stirring bifidobacterium freeze-dried powder, vegetable oil, suspending agent and wetting agent. In addition, the capsule shell has colonic solubility by impregnating the soft capsule with formaldehyde. The invention encapsulates the bifidobacterium freeze-dried powder soft capsule with vegetable oil as the carrier, has the effect of dissolving the colon, has good product stability, is convenient for transportation and storage, prolongs the shelf life, and jointly acts the bifidobacteria and vegetable oil on the colon , improve the disorder of intestinal flora, achieve the effect of laxative, and solve the pain caused by constipation. The invention is applied to the field of preparation of probiotics.

A plant extract composition for treating myopia and visual fatigue contains cowberry fruit extract (10-99 wt.%), ginkgo leaf extract (1-90 wt.%) and starch (0-50 wt%). It is prepared through crushingcowberry fruit, boiling in water at 45-80 deg.C for removing pection, adding alcohol, concentrating to obtain its extract, thermal extracting twice of ginkgo leaf, adding alcohol, recovering alcohol solution, concentrating to obtain its extract, then proportionally mixing three of them, and packaging. Its advantages are high effect and high safety.

The invention relates to the field of medicine, in particular to a composition and application thereof to the preparation of a product for improving chloasma. The composition provided by the invention comprises a Chinese angelica extract, a stem cell extract A and a stem cell extract B. Experiments show that the composition provided by the invention can reduce the relative activity of tyrosinase to be 89.8% and reduce the relative content of melanin in cells to be 82.8%, so that the composition provided by the invention can effectively inhibit the activity of the tyrosinase and reduce the melanin content of the cells. The effects are obviously more excellent than those of a control group which gives the Chinese angelica extract singly or gives the stem cell extract singly. In addition, the composition provided by the invention is used for improving the chloasma, the effective rate can reach 95% and the remission rate can reach 70%.

This invention provides a method for accelerating the proliferation of human mesenchymal stem cells, which comprises the steps of: transfecting recombinant expression carrier containing EGF to human mesenchymal stem cells, and stimulating with a certain concentration of calcium ions during the transfection process to divide into typical stem cells. Under nude mouse subcutaneous microenvironment induction, the stem cells are further divided into skin tissue stem cells, thus directly taking part in the proliferation of nude mouse hair. This invention can obtain rapidly proliferated human mesenchymal stem cells, thus having a potential application in clinical skin wound treatment.

The invention discloses a traditional Chinese medicine combination used for treating rheumatic heart disease and pertains to the Chinese medicine field. The Chinese medicine preparation takes the following ingredients as the active ingredients: root of rehmannia, radix codonopsis pilosulae, red sage root, fourstamen stephania root, medical glue, radices polygonati officinalis, lilyturf root, cassia twig, fructus schizandrae, liquorice and wu chia pee. The traditional Chinese medicine combination used for treating rheumatic heart disease have the effects of benefiting vital energy, enriching the blood, enheartening the heart-yang, nourishing the heart, benefiting the pulse, promoting blood circulation by removing blood stasis and repairing an impaired heart valve.

A health-care tea suitable for the patients of neurasthenia, dizziness, insomnia, hypomensia, heart failure, cough, etc is prepared from prepared rehmannia root, wild jujube, phtheirospermum root, henry woodbetong root and crystal sugar.

The invention belongs to the field of medicine and personal care, and particularly relates to propolis-aloe bacteriostatic gel and a preparation method thereof. The propolis-aloe bacteriostatic gel isprepared from the following raw materials in percentage by mass: 8-12% of golden cypress, 8-10% of fructus cnidii, 6-11% of stemona, 9-12% of fructus kochiae, 7-9% of divaricate saposhnikovia roots,4-8% of seaweeds, 3-6% of aloes, 0.5-0.8% of propolis, 1-1.4% of chlorhexidine acetate, 0.8-1.2% of carbomer 940, 0.08-0.11% of methylparaben, 0.09-0.12% of triethanolamine, 0.9-2.1% of ethanol and 36-40% of purified water. The propolis-aloe bacteriostatic gel is propolis-aloe gel prepared through the compound compatibility of the propolis and the aloes, through the synergistic effect of the propolis and the aloes, the effects of inhibiting the growth of bacteria, promoting wound healing, diminishing inflammation, realizing sterilization, realizing moistening and nourishing, replenishing water, removing acne, removing eczema and realizing spot-fading can be effectively achieved, and especially, the bacteriostatic effect on escherichia coli, staphylococcus aureus, hemolytic streptococcus and the like is achieved.

The invention discloses a preparation method of traditional Chinese medicinal submicron powder for animals. The method comprises the following steps: 1, cleaning ; 2, slicing: cutting crisp and frangible traditional Chinese medicines into thick slices or long segments, and cutting solid or high-toughness traditional Chinese medicines into slices or short segments; 3, medicinal material division: dividing the above sliced medicinal materials into high temperature resistant traditional Chinese medicinal materials and traditional Chinese medicinal materials not resistant to high temperatures; 4, drying; 5, preliminary crushing: crushing the dried high temperature resistant traditional Chinese medicinal materials by adopting a hammer type crusher, and crushing the traditional Chinese medicinal materials not resistant to high temperatures by adopting an air-cooled universal crusher; and 6, micronization: adding the preliminarily-crushed traditional Chinese medicinal material particles into an ultrasonic airflow crusher, and further crushing to prepare the traditional Chinese medicinal submicron powder for animals. The method is in favor of reserving the bioactive components of the traditional Chinese medicines, and the prepared submicron powder for animals has the characteristics of high mixing uniformity, use convenience, high bioavailability and good palatability; and the method has the advantages of simple operation, low energy consumption, low emission, and low production cost, and is more suitable for the large scale production.

The invention provides a method for preparing autologous hematopoietic stem cells. The method includes following steps of cultivating somatic cells in a cell culture fluid for 3-6 days and collecting the generated autologous hematopoietic stem cells. The cell culture fluid is an RPMI1640 culture fluid containing: 1-100 [mu]M of Y-27632 (C14H21N3O.2HCl), 1-100 ng/ml of stem cell factors, 1-100 ng/ml of interleukin 3, 1-100 ng/ml of interleukin 6, 1-100 ng/ml of interleukin 11, 1-100 ng/ml of a macrophage colony stimulating factor (M-CSF), 1-100 ng/ml of a granulocyte colony-stimulating factor (G-CSF), 1-100 [mu]g/ml of fucoidin, 1-100 [mu]g/ml of dextran sulfate, 1-100 nM of AMD3100 (1,1'-[1,4-phenylenebis(methylene)]-bis-1,4,8,11-tetrazacyclotetradecane), 1-100 [mu]M of M-alendronate sodium (Malendronate sodium trihydrate), and 1-100 [mu]M of disodium pamidronate. The invention provides a method for preparing the autologous hematopoietic stem cells, a kit, the stem cells and an application. In addition, the method is advantaged in yield, purity, and producing speed of the production of the protein-induced autologous hematopoietic stem cells.

The invention relates to a composition for an oral cavity and application and a preparation method of the composition. The composition comprises the following components in parts by weight: 0.1-1 partof a lemon extract, 0.1-2 parts of a propolis extract, 0.05-0.8 part of a tea leaf extract, 0.5-5 parts of sea salt, 0.1-5 parts of an Aloe vera extract, 0.05-0.8 part of melaleuca alternifolia essential oil, 0.06-1 part of a white birch bark extract and 0.02-1 part of a mangnolia officinalis bark extract. By selecting components, on the basis of medicinal principles of different components, withthe combination of the components of a specific ratio, and by virtue of sufficient synergetic effects of the components, the composition provided by the invention has efficient effects of inhibitingbacteria, eliminating helicobacter pylori, relieving gum inflammation and treating ozostomia; meanwhile, the composition provided by the invention is reasonable in cost, simple and convenient to prepare, safe to use, relatively good in universality and relatively applicable to commercial popularization.

The invention discloses a traditional Chinese medicine for treating anemia. The traditional Chinese medicine comprises the following components in part by weight: 50 to 100 parts of barbary wolfberry fruit, 50 to 100 parts of Chinese date, 50 to 100 parts of virgate wormwood herb, 50 to 100 parts of honeysuckles, 50 to 100 parts of donkey-hide glue, 50 to 100 parts of black sesame, 50 to 100 parts of longan, 40 to 80 parts of Chinese lobelia herb, 40 to 80 parts of astragals, 40 to 80 parts of scrophularia root, 40 to 80 parts of hairyvein agrimonia herb and bud, 40 to 80 parts of isatis indigotica fort, 40 to 80 parts of rehmanniae praeparatum, 40 to 80 parts of dwarf lilyturf tuber, 40 to 80 parts of weeping forsythiae capsule, 45 to 85 parts of houttuynia, 45 to 85 parts of gardenia, 5 to 85 parts of Indian buead,45 to 85 parts of golden thread and proper amount of honey and dextrine. The components of the traditional Chinese medicine for treating anemia are prepared into the medicament by processes of crushing, extracting, mixing, pelleting and the like. The formula of the traditional Chinese medicine has very good treatment effect on people with anemia and qi-blood deficiency and also has relatively good adjuvant treatment effect on patients with leukemia.

Dispersing Qingkailing tablet as one pure Chinese medicine preparation has obvious curative effect on viral cold, acute tonsillitis, acute pharyngitis, acute bronchitis, high fever, etc. It has the functions of clearing away heat and toxic material and tranqilizing, and may be also used in treating high intracranial pressure disease, hydrocephalus, cerebral vascular dementia and other diseases. The medicine has high bioavailability, fast absorption and taking convenience. The present invention features that the dispersing Qingkailing tablet is prepared with eight kinds of Chinese medicinal materials, including cholic acid, baicalin, cape jasmine, isatis root, hyodeoxycholic acid, etc. as well as ten kinds of supplementary material, and through soaking, decoction, filtering, concentrating, deposition, crushing, drying, palletizing, finishing and other steps.

Disclosed is a dripping pills of six ingredients with Rehmanniae, which is prepared from dried rehmannia root, cornus officinalis, rhizoma dioscoreae, bark of peony root, Poria cocos, alisol as raw material as well as base material through the following steps, (1) distilling bark of peony root with water to extract volatile oil, (2) extracting cornus officinalis with 70% ethanol, concentrating to obtain concrete, (3) boiling rehmannia root, rhizoma dioscoreae with water, purifying with 70% ethanol, concentrating the alcohol liquid to obtain concrete, (4) steeping poria cocos to obtain extract, (5) merging the extract and spraying volatile oil, charging right amount of twain-80 to prepared plaster- solution, heating polyethylene glycol, charging in thick grease and volatile fluid, stirring homogeneously, instilling into fluid wax (0-5 deg. C), thus preparing drop pills.

This invention relates to an osteogenic device for the de novo induction of bone formation in a mammal. The device contains a at least one transforming growth factor—&bgr;3 isoform and a retention matrix. The device is introduced by direct injection or surgical implantation into an area where de novo bone formation is desired and, once implanted, the retention matrix acts to retain the TGF-&bgr;3 isoform at its place of introduction and forms a scaffold for generated bone, the induction of which is promoted by the TGF-&bgr;3 isoform. The device may be used to induce bone growth where bone has been debrided in a surgical procedure and it may also be used to transform neoplastic primary and/or metastatic secondary masses into bone thus facilitating surgical debridement thereof.

The invention provides application of N-acetyl-D-glucosamine or pharmaceutically acceptable salt thereof in preparation of a microecological preparation for preventing and treating irritable bowel syndrome or in preparation of a bifidobacterium activity improver. The invention provides a new application of N-acetyl-D-glucosamine, develops the application field of N-acetyl-D-glucosamine, has a goodeffect on multiple factors causing irritable bowel syndrome, can effectively prevent and treat irritable bowel syndrome, obviously improves symptoms, and has no toxic or side effect.

The invention relates to a Chinese medicinal preparation for treating spermophlebectasia, wherein the reactive constituents are prepared from the following raw materials (by weight portion): ledebouriella root 6-12, dahurian angelica root 6-9, dried orange peel 8-10, red peony root 6-9, Chinese angelica root 9-12, pangolin scales 9-12, Chinese honey locust 9-12, myrrh 3-5, licorice root 4-6, honeysuckle flower 10-15, root of Chinese trichosannthes 10-15, bupleurum root 4-6, Sichuan fritillary bulb 9-12, frank incense 3-6, phellodendron bark 8-10, plantain seeds 8-10. The medicament can be prepared into dose forms of oral liquids, capsules, tablets, pills or powders.

The invention discloses a dispersible tablet for clearing heat, relieving sore-throat, detoxifying and relieving pain, and a preparation method for the same. The dispersible tablet contains the following ingredients in parts by weight: 350 parts of honeysuckle, 200 parts of blackberry lily, 250 parts of arrowshaped tinospora root, 250 parts of platycodon grandiflorum, 250 parts of radix scrophulariae, 250 parts of radix ophiopogonis, 1 part of calculus bovis, and 0.5 parts of borneol. According to the dispersible tablet and the preparation method for the same disclosed by the invention, the medicines except calculus bovis and borneol are prepared into dry paste powder, the dry paste powder is 51.8 parts by weight, and the dry paste powder comprises the raw materials and auxiliary materials in the following parts by weight: 10 parts of sodium carboxymethyl starch, 13.2 parts of polyvinylpolypyrrolidone, 24 parts of microcrystalline cellulose, 0.5 parts of magnesium stearate, 0.5 parts of aerosil, and 50 parts of ethanol. The dispersible tablet disclosed by the invention is a pure traditional Chinese medicine composition oral solid preparation, and prepared according to the compatible principle of traditional Chinese medicine prescriptions; and the dispersible tablet has the effects of clearing heat, relieving sore-throat, detoxifying and relieving pain.

The invention provides a pharmaceutical composition for treating diabetic retinopathy. The pharmaceutical composition is a preparation prepared from the following crude medicinal materials by weight: 17-23g of pollen typhae, 3-7g of cinnamon, 7-13 baked ginger, 3-7g of angelica sinensis, 7-13g of motherwort, 7-13g of fructus broussonetiae, 7-13g of thunberg fritillary bulb, 7-13g of cuscuta japonica and 7-13g of turtle shell. The invention also provides a preparation method and use of the pharmaceutical composition. The pharmaceutical composition provided by the invention has a good treatment or disease development inhibition effect on the diabetic retinopathy or diabetic macular edema, the subjective symptoms of a sufferer can be improved, the living quality of the sufferer is improved, and a new choice is provided for clinical medication.

The invention discloses a traditional Chinese medicine composition for preventing and treating epidemic meningitis. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 7-11 parts of raw rhubarb, 7-11 parts of mirabilite, 10-14 parts of immature bitter orange, 1-5 parts of mangnolia officinalis, 1-3 parts of purple snow elixir, 1.5-3.5 parts of rhinoceros horn, 12-17 parts of rhizoma anemarrhenae and 18-22 parts of lalang grass rhizome. The preparation method comprises the following steps: putting weighed the raw rhubarb, the mirabilite, the immature bitter orange, the mangnolia officinalis, the purple snow elixir, the rhinoceros horn, the rhizoma anemarrhenae and the lalang grass rhizome into a container; adding 8-fold water to decoct for 1.5 hours; filtering; adding 6-fold water to a residue; decocting for an hour; filtering, and merging filtrate; concentrating, drying and loading in capsule shells. A clinical experiment proves that the epidemic meningitis can be safely and effectively treated by the traditional Chinese medicine composition.

The invention discloses an arthralgia and myalgia patch and a manufacturing method thereof. An ointment comprises, by weight, 290-310 parts of Chinese clematis roots, 115-135 parts of Chinese angelicaroots, 115-135 parts of fortune's drynaria rhizomes, 25-35 parts of incised notopterygium rhizomes and roots, 25-35 parts of doubleteeth pubescent angelica roots,55-56 parts of chuanxiong rhizomes, 25-35 parts of Himalayan teasel roots, 25-35 parts of medicinal cyathula roots, 25-35 parts of tall gastrodia rhizomes, 5-15 parts of pangolin scales, 25-35 parts of slenderstyle acanthopanax roots andbarks, 5-15 parts of dragon's blood, 25-35 parts of Solamum melongena, 15-25 parts of prepared Chinese monkshood roots, 15-25 parts of prepared kusnezoff monkshood roots, 25-35 parts of fresh reddishjackinthepulpit rhizomes, 25-35 parts of fresh ternate pinellia rhizomes, 25-35 parts of white mulberry barks, 25-35 parts of dahuria gentian roots, 25-35 parts of olibanum, 90-110 parts of borneol,25-35 parts of camphor and 10 parts of wild mint oil. A formula of the paste can effectively control pain, restrain hyperostosis and treat bone diseases. According to the manufacturing method of the paste, 90% of effective components are extracted through ethyl alcohol, effective components in medicinal materials can be efficiently extracted through an extracting process, the utilization ratio ofthe medicinal materials is increased, and cost is reduced.

The invention which discloses a traditional Chinese medicinal pill for treating viral meningitis relates to the technical field of traditional Chinese medicines. The traditional Chinese medicinal pill for treating viral meningitis comprises the following raw materials, by weight, 5-50 parts of an extract of a component A, 10-100 parts of a Radix notoginseng paste, 10-100 parts of barbat skullcap powder, 50-300 parts of Cornu Bubali powder, 50-200 parts of a deer horn gelatin, 30-100 parts of cornu cervi degelatinatum, and 50-150 parts of sophora flavescens powder, and the component A comprises raw materials of a Korean pine branch, a birch branch, and a poplar branch with the weight ratio of 1:1-4:1-4. The traditional Chinese medicinal pill has the advantages of heat clearing and detoxifying, right supporting and evil dispelling, and viral meningitis treating. Patients have good medicinal survivability and no anaphylactic reactions of rash and the like after using the pill, no symptoms of gastrointestinal discomfort, diarrhoea and the like appear in the pill taking period, and hepatic and renal function indexes before and after taking the pill are normal.