32 results about "Polysaccharide" patented technology

The invention relates to a method of treatment of resistance to platelet inhibitors, i.e. a method to overcome resistance of treatment with platelet inhibitors, said method comprising administering a therapeutically effective amount of dipyridamole in combination with a platelet inhibitor and, optionally, in combination with a third antithrombotic component such as direct thrombin inhibitors, factor Xa inhibitors, combined thrombin/factor Xa inhibitors, heparin, low molecular weight heparin, argatroban, bivalrudin, hirulog or polyglycans to a patient in need thereof. The invention further relates to the use of dipyridamole for the manufacture of a pharmaceutical composition for treatment of resistance to platelet inhibitors. The invention also relates to a method to diagnose resistance to treatment with platelet inhibitors, said method comprising measurement of the density of binding of Annexin V on platelets.

The subject invention is directed to a pharmaceutical composition comprising an open matrix network carrying a pharmaceutically active ingredient, wherein the open matrix network comprises both the polysaccharides levan and inulin.

The invention provides preparation and application of nano zeolite reinforced xanthan gum composite hydrogel functional microspheres. The method selects a nanoscale zeolite molecular sieve which is synthesized by a template-free and low-cost manner, then premixes the nanoscale zeolite molecular sieve into a xanthan gum-sodium alga acid binary natural polysaccharide aqueous solution to prepare nano zeolite molecular sieve reinforced organic-inorganic composite hydrogel functional microspheres. Corresponding nano zeolite has a clear synergetic heavy metal adsorbing behavior; meanwhile, a corresponding xanthan gum-sodium alga acid binary polysaccharide cross-linking matrix has a richer micro three-dimensional network structure, thus micro channels of the nano zeolite, which are evenly distributed, directionally interact with polysaccharide molecular characteristic functional groups. The prepared microspheres have satisfactory effects of absorbing and removing cobalt ions and nickel ions in simulation nuclear industry wastewater.

A series of amphiphilic polymer materials which take pulullan as a main chain and polyester as a branch chain are synthesized. By adopting a novel synthetic method, the synthetic time of the series of amphiphilic polymer materials is shortened to 5 minutes, so that the materials have a relatively high industrial value. The series of amphiphilic polymer materials have multi-aspect application values in the field of medicine transfer such as microsphere and nanoparticle reparations and the like as well as modification of other medicine transfer systems and the like. The series of amphiphilic polymer materials are used for preparing nanoparticles and microsphere conveying transfer medicine or modification medicine transfer carriers such as nanoparticles and microspheres so as to achieve the purpose of increasing the solubility and stability of medicines, improving the curative effect of the medicines and reducing the toxic and side effects of the medicines. The series of materials, which are used as the medicine transfer carriers or modification medicine transfer carriers, can be used for achieving the purpose of liver targeting delivery and temperature sensitive control released delivery at the same time.

The invention provides a method for preparing autologous hematopoietic stem cells. The method includes following steps of cultivating somatic cells in a cell culture fluid for 3-6 days and collecting the generated autologous hematopoietic stem cells. The cell culture fluid is an RPMI1640 culture fluid containing: 1-100 [mu]M of Y-27632 (C14H21N3O.2HCl), 1-100 ng/ml of stem cell factors, 1-100 ng/ml of interleukin 3, 1-100 ng/ml of interleukin 6, 1-100 ng/ml of interleukin 11, 1-100 ng/ml of a macrophage colony stimulating factor (M-CSF), 1-100 ng/ml of a granulocyte colony-stimulating factor (G-CSF), 1-100 [mu]g/ml of fucoidin, 1-100 [mu]g/ml of dextran sulfate, 1-100 nM of AMD3100 (1,1'-[1,4-phenylenebis(methylene)]-bis-1,4,8,11-tetrazacyclotetradecane), 1-100 [mu]M of M-alendronate sodium (Malendronate sodium trihydrate), and 1-100 [mu]M of disodium pamidronate. The invention provides a method for preparing the autologous hematopoietic stem cells, a kit, the stem cells and an application. In addition, the method is advantaged in yield, purity, and producing speed of the production of the protein-induced autologous hematopoietic stem cells.

The invention relates to a method for preparing composite yeast nutritious drinks, and belongs to the technical field of nutritious drinks. According to the technical scheme, the method includes the steps that lyceum barbarum extract is prepared; a yeast extract solution is prepared; syrup feed liquid is prepared; the obtained lyceum barbarum extract and the yeast extract solution are added to the syrup feed liquid, the lyceum barbarum extract, the yeast extract solution and the liquid are evenly mixed, sodium erythorbate is added to the mixed solution, and high pressure homogenization is conducted on the mixed solution; the solution after high pressure homogenization processing is sterilized, filtered and clarified through a ceramic membrane, and filled into vessels, and then the composite yeast nutritious drinks are prepared. The prepared lyceum barbarum and yeast nutritious drinks have quite rich nutrient substances, lyceum barbarum contains a lot of nutrients such as amino acids, lyceum barbarum polysaccharides, inorganic salt, glucose, taurine and betaine, and the nutrients are essential to human body; yeast extract contains 18 kinds of amino acids and polypeptides, multiple B vitamins, nucleic acids and multiple mineral elements. The prepared drinks have the functions of nourishing the kidney and tonifying the liver, benefiting qi and promoting the production of body fluid, improving eyesight and soothing nerves, resisting fatigue and improving human body immunity.

The invention discloses a polyester/polyethyleneglycol block copolymer containing hydroxyl pendant group and application of the polyester/polyethyleneglycol block copolymer. The copolymer is an ABA type, (AB)2-100 type, AB type or BAB type block copolymer composed of the hydrophobic polyester block A containing the hydroxyl pendant group and the hydrophilic polyethyleneglycol block by mass ratio. The copolymer can be assembled into nano-particles in a water medium and used for entrapping drugs, protein, polypeptide and polysaccharide, and can also react with active functional groups to obtain other functional copolymers. The copolymer has good biological compatibility and biodegradablility, is easy to be assembled to form the nano-particles in water, and can be used as a carrier of drugs. The hydroxyl of the polyester block is an active group and can be subjected to bonding reaction with various biological factors, drugs or other functional groups, and therefore, application range of the nano-particles is expanded.

The invention relates to an oil-in-water (O/W) emulsions that can be aerated to produce foamed emulsions. More particularly, the invention relates to an aeratable or aerated O/W emulsion comprising a continuous aqueous phase and a dispersed oil phase, said emulsion containing:

• • 25-55 wt. % water;
  • 4-50 wt. % oil;
  • 3-12 wt. % of cyclodextrin selected from alpha-cyclodextrin, beta-cyclodextrin and combinations thereof;
  • 20-60 wt. % of saccharides selected from monosaccharides, disaccharides, non-cyclic oligosaccharides, sugar alcohols and combinations thereof;
  • 1-20 wt. % of polysaccharides;
  • 0-30 wt. % of other edible ingredients;

wherein the saccharides are contained in the emulsion in a concentration of at least 60% by weight of water and wherein the polysaccharides are contained in the emulsion in a concentration at least 2% by weight of water.

The O/W emulsions are capable of forming foamed emulsions with high firmness and excellent shape retaining properties. These foamed emulsions further offer the advantage that they exhibit excellent stability.

The invention discloses an anti-aging health care skin care product and a preparation method thereof. The raw material of the skin care product comprises natural active ingredients and auxiliary materials,and the natural active ingredients are composed of phellodendri extracts,cortex dictam extracts,safflower extracts and inonotus obliquus polysaccharide. The anti-aging health care skin care product comprises a specific weight composition of the phellodendri extracts,the cortex dictam extracts,the safflower extracts and the inonotus obliquus polysaccharide,the proportion of each component is controlled,and in addition to giving full play to respective basic functions of each component,the components can synergistically increase efficiency,effectively regulate human endocrine secretion,andfundamentally play an anti-aging role. The skin care product has excellent anti-aging effects and is suitable for people whose skin is prone to aging.

The disclosure relates to an extraction method and application of phellinus igniarius polysaccharide. The method comprises the following steps: (1) crushing mature phellinus igniarius fruit bodies, performing sieving, and preparing a culture medium; (2) inoculating cellulose degrading bacteria and Paenibacillus polymyxa into the culture medium in the step (1) and performing fermentation for a certain period of time; (3) after the fermentation is completed, performing solid-liquid separation of bacteria and water-insoluble impurities to obtain a fermentation solution in which polysaccharide isdissolved; and washing a precipitate after solid-liquid separation, and combining a washing solution into the fermentation solution in which polysaccharide is dissolved; (4) performing ultrafiltrationon the mixed solution obtained in the step (3); and (5) performing precipitation by using an ethanol solution to obtain the phellinus igniarius polysaccharide product. The yield and purity of the phellinus igniarius polysaccharide product obtained by the method are relatively high, and the antioxidant ability is relatively high.

The invention belongs to the field of wine brewing, in particular relates to a brewing method, and more particularly relates to a brewing method of agaricus bisporus and chenopodium quinata wine. According to the brewing method, agaricus bisporus and chenopodium quinata are used as raw materials, novel wine is prepared through fermentation, and the efficacies of reducing blood glucose, lowering blood pressure, reducing blood fat, resisting oxidation, resisting cancer, improving body immunity, relieving cough and reducing sputum, inducing diuresis and relaxing the bowels, expelling toxins and losing weight, and the like are enhanced; due to the adoption of the extrusion puffing method for pretreating chenopodium quinate, the utilization rate of chenopodium quinata is increased, and the costis reduced; the agaricus bisporus and chenopodium quinata wine contains rich nutritional ingredients including amino acids, unsaturated fatty acids, vitamins, minerals and polysaccharides, is convenient to use, is pure and soft in taste, is suitable for wide consumers, and has the broad market and development prospects.

The invention provides an extraction method for phellinus vaninii polysaccharide. The method comprises the following steps: crushing a phellinus vaninii fruiting body to 1-5 mesh, performing soaking in physiological saline for 8-24 h, performing centrifugation, and collecting residues; boiling the residues of the phellinus vaninii fruiting body in boiling water at 110-130 DEG C for 20-40 min, performing centrifugation, and collecting residues; adding water into the residues, performing freezing for 24-36 h, and performing unfreezing; adding water into the unfrozen mixture to obtain a mixed liquid, adding a complex enzyme into the mixed liquid, performing enzymatic hydrolysis at 50-60 DEG C for 2-4 h, and performing centrifugal separation to obtain a supernatant liquid; and finally, performing adsorption on the supernatant liquid by using resin, performing dialysis, performing concentration, and performing freeze drying to obtain the phellinus vaninii polysaccharide. According to the extraction method for the phellinus vaninii polysaccharide provided by the invention, the extracted phellinus vaninii polysaccharide has obvious activity of inhibiting tumor cell proliferation, has goodbiocompatibility compared with a polysaccharide extracted and purified by a chemical method, and does not bring an inflammatory reaction; and the phellinus vaninii polysaccharide provided by the invention can be used in anti-tumor drugs or health-care products.

The invention discloses an environmentally-friendly freshness-keeping agent for meat products and an application of the environmentally-friendly freshness-keeping agent for meat products in meat foodpreservation. The environmentally-friendly freshness-keeping agent for meat products comprises the following ingredients in parts by weight: 20-50 parts of agaricus bisporus polysaccharides, 40-80 parts of sodium alginate, 0.02-0.2 part of calcium propionate, 0.005-0.05 part of lactic acid, 1-5 parts of glycerine, and 300-900 parts of water. The environmentally-friendly freshness-keeping agent formeat products disclosed by the invention is scientific and reasonable in formula, good in freshness-keeping effects and capable of effectively inhibiting reproduction of microorganisms in meat so asto prevent and treat microbial contamination on meat; and thus, the environmentally-friendly freshness-keeping agent for meat products is capable of effectively prolonging shelf lives of meat products, improving quality of meat products and effectively reducing fresh meat storage costs.

The invention discloses a wild ganoderma product for resisting cancer and tumor and removing liver toxin and a preparation technology. According to the invention, wild ganoderma lucidum is adopted asraw material, and the wild ganoderma product for resisting cancer and tumor and removing liver toxin is finally prepared by the steps of washing, sterilizing, drying and dicing and the like. The product has the advantages of inhibiting cancer cell growth, attending acute and chronic hepatitis, early cirrhosis, esophageal cancer, lung cancer, liver cancer, nasopharyngeal carcinoma, pancreatic cancer, neurasthenia, intestinal diarrhea, rheumatoid tuberculosis,diabetes, gastrointestinal diseases, nourishing physical, lowering blood sugar, moistening the lungs and kidneys, maintaining beauty and keeping young, enhancing immunity, and enriches in ergosterol, ganoderic acid, ganoderma lucidum polysaccharides, amino acids, polypeptides, adenosine, triterpenoids and various trace elements, whereinthe organic germanium content is as high as 12380 ppm and the organic selenium content is also high. The product can be made into five-color ganoderma lucidum tea, ganoderma lucidum beverage, ganoderma lucidum oral liquid, five-color ganoderma lucidum wine, and other homologous products of medicines and foods. The product provided by the invention can also be made into traditional Chinese medicine prescriptions such as paste, pill and pellet.

The invention discloses a Radix pueraiae fermentation protoplasm cosmetic product and a preparation method and application thereof. The preparation method includes following steps: using Radix pueraiae as a substrate and brewer's yeast as a strain for fermentation. Radix pueraiae fermentation protoplasm prepared by the method also belongs to the protection range of the invention.an active ingredient of the cosmetic product is the Radix pueraiae fermentation protoplasm. Functions of the cosmetic product includes (a) and/or (b) and/or (c) and/or (d), (a) refers to resisting oxidation, (b) refers to removing DPPH free radicals, (c) refers to promoting collagen synthesis, and (d) refers to resisting aging. Fermentation engineering technology is utilized to extract active substance from Radix pueraiae, so that operation is simple; no foreign substance is added, so that the Radix pueraiae fermentation protoplasm prepared by the method is safe and harmless to skin. The cosmetic product is rich in substances like polysaccharide and flavone which are synergistic with fermentation product ingredients in fermentation filtrate, so that resistance to oxidation and aging can be improved remarkably.

The invention discloses a cosmetic dressing composition based on marine organisms and a preparation method of the composition. The composition comprises the following raw materials in parts by weight:106-116 parts of sea lettuce, 49-88 parts of scytosiphon lomentaria, 12-19 parts of hyaluronic acid, 4-9 parts of ganoderma lucidum polysaccharide, 2-4 parts of oleanolic acid, 13-18 parts of sapindus saponin, 10-20 parts of cocoamidopropyl betaine, 8-11 parts of calendula extract, 3-5 parts of sodium carboxymethyl cellulose, 11-14 parts of lavender essential oil, 3-6 parts of Vc magnesium phosphate, 25-36 parts of honey and 2-5 parts of dry yeast. The cosmetic dressing composition based on marine organisms is capable of effectively delaying aging.

Chitosan-based nail formulations are useful to treat nail inflammatory diseases such as psoriasis, atopic dermatitis and lichen planus. The chitosan is normally in the form of an amino-polysaccharide derivative, preferably water soluble, such as hydroxypropyl chitosan. The formulation may be a nail lacquer, a spray, a cream, an ointment, a gel, a lotion or a foam and may comprise chitosan, a chitosan derivative or a salt thereof in an amount from 0.1 to 25 wt. % with respect to the total weight of the formulation.

The invention discloses a feed for enhancing the immunity and disease resistance of poults, which is prepared from the following materials in parts by weight: corn, wheat bran, peanut hull powder, carrot, pumpkin, zucchini, bone meal, shrimp shell meal, table salt, honeysuckle flower, plantain herb, officinal magnolia bark, Chinese atractylodes rhizome, thinleaf buckthorn fruit, common andrographis herb, probiotics, saccharomycete, cellulase and amylase. According to the feed for enhancing the immunity and disease resistance of the poults, since the feed is combined with the traditional Chinese medicine composition, the feed utilization rate is high, the feed can help avian animals to digest feed ingredients which cannot be digested and cannot be completely digested by avian animals, and decompose substances in the feed, such as phytate and polysaccharide, so that nutrition in the feed can be sufficiently released, moreover, the immunity and disease resistance of avian animals can be enhanced, the incidence rate of poultry can be decreased, the growth of the poults can be promoted, and the survival rate of the poults can be increased.

The invention discloses equipment for purifying polysaccharide composition from edible fungus precooking liquid. The equipment comprises a base plate, wherein a first tank body is fixedly connected tothe top of the base plate; a second tank body is fixedly connected to the bottom of the inner wall of the first tank body; a first protecting cover is fixedly connected to one side of the first tankbody; a second protecting cover is fixedly connected between the other side of the first tank body and the top of the base plate; first motors are fixedly connected to two sides of the first tank bodyby connecting blocks; a first belt wheel is arranged at one end of an output shaft of each first motor in a sleeving manner; a second belt wheel is in driving connection with the outer surface of each first belt wheel by a belt. The invention relates to the technical field of purification equipment. According to the equipment and a method for purifying the polysaccharide composition from the edible fungus precooking liquid, sufficient stirring in the purifying process can be realized, so that heating and purification can be quicker and more sufficient, time is saved, and purification efficiency and working efficiency of workers are improved.

The invention discloses a detection method for diglycolamine residues The detection detection method comprises the following steps of: extracting diglycolamine in a to-be-detected sample by using an ultrasonic extraction method, and detecting the diglycolamine residues by using a gas chromatograph. The detection method of the diglycolamine residues is simple in operation, convenient in sample preparation, sensitive in response and good in separation degree, and can be used for rapidly and accurately detecting the diglycolamine residues in the polysaccharide.