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136 results about "Active ingredient" patented technology

An active ingredient (AI) is the ingredient in a pharmaceutical drug or pesticide that is biologically active. The similar terms active pharmaceutical ingredient (API) and bulk active are also used in medicine, and the term active substance may be used for natural products. Some medication products may contain more than one active ingredient. The traditional word for the API is pharmacon or pharmakon (from Greek: φάρμακον, adapted from pharmacos) which originally denoted a magical substance or drug.

Edible mushroom, spent mushroom substrate and probiotics-containing nutrient solution for livestock and poultry and preparation method thereof

The invention relates to an edible mushroom, spent mushroom substrate and probiotics-containing nutrient solution for livestock and poultry and a preparation method thereof. The preparation method comprises the following steps of: preparing leach liquor by using waste spent mushroom substrates as raw materials, extracting a plurality of active ingredients from the spent mushroom substrates, and then fermenting and preparing the nutrient solution containing a plurality of microorganisms beneficial for the growth of the livestock and poultry by using the leach liquor as a culture medium. The prepared nutrient solution is brown in color and tart, slightly has the incenses of edible mushrooms, and contains abundant probiotics groups so as to be beneficial for enhancing the appetite of the livestock and poultry and promoting the absorption of nourishment and the growth of the livestock and poultry. Compared with the solid fermentation of the conventional preparation method of spent mushroom substrate-containing feeds, due to the adoption of the main production method of liquid fermentation, the preparation method of the nutrient solution has the advantages of environmental protection, energy saving and convenient operation; and the obtained product is liquid so as to have the advantages of convenient application and favorable palatability for the livestock and poultry.
Owner:大连春天生物技术有限公司

Glutamic acid synergist urea and preparation method thereof

InactiveCN102584497AIncrease profitReduce churnFertilizer mixturesGrowth promotionNitrogen
The invention relates to a glutamic acid synergist urea and a preparation method of glutamic acid synergist urea. The glutamic acid synergist urea provided by the invention consists of a glutamic acid synergist and urea. The production method of the glutamic acid synergist urea comprises the steps of preparation of the glutamic acid synergist, preparation of glutamic acid synergist urea, high tower cooling granulation and the like. By the fertilizer growth promotion effect of active ingredients in the glutamic acid synergist of the fertilizer on crops, the storage state of nitrogen elements in the plants can be improved, the ability of the crops to absorb nutrients is strengthened, the crop yield and the crop quality are improved, the utilization ratio of the fertilizer is increased (by 5%-10%), the loss of soil nutrients is reduced, and secondary pollution is avoided. The fertilizer product prepared by the invention is wide in source of raw materials, and has excellent application prospect.
Owner:INST OF AGRI RESOURCES & REGIONAL PLANNING CHINESE ACADEMY OF AGRI SCI

Method for preparing LCZ696

ActiveCN105330609AReduce generationPrecipitation state is goodOrganic compound preparationOrganic chemistry methodsSodium acetateReaction temperature
The invention discloses a method for preparing LCZ696. Please see the synthesis route in the specification. When sodium acetate is used as alkali in the compound III preparation process, the conversion rate is high, hydrolysis impurities are few, system stability is good, and the reaction time is greatly shortened; in the compound I preparation process, acetone and normal heptanes with the mass ratio between 5 to 1and 10 to 1 serve as cocrystallization solvent, the reaction temperature of 35-45 DEG C is adopted, a sodium hydroxide solution is dropwise added into a reaction system at a certain speed at the temperature of 35-45 DEG C, generation of hydrolysis products can be greatly reduced, the solid precipitation state is good, purity is high, aminolysis impurities and hydrolysis impurities can be effectively controlled, and the LCZ696 can directly serve as crude drug to be used for preparations.
Owner:NANJING CHIA TAI TIANQING PHARMA +1

Anti-aging repair mask

InactiveCN107308039ARegulates the skinRepair skinCosmetic preparationsOrganic active ingredientsBetaineInjury Site
The invention discloses an anti-aging repair facial mask, which comprises components such as diterpene from basil, flavone from Budisma flavonoids, flavonoids from kapok, glycerin, butanediol, betaine, trehalose, nicotinamide and the like. Adding natural diterpenoids, flavonoids and flavonoids active ingredients in the facial mask can effectively interrupt the peroxidation chain reaction, remove free radicals, chelate metal ions, and regulate inflammatory cells to achieve Delays cell aging, repairs and prevents cell damage; in addition, the flavonoids of Budisma can activate its repair genes, promote the repair of damaged parts, and prevent inflammation from expanding or lasting too long. The secretion and transfer of semaphorin indirectly regulates the occurrence of repair and inflammation, and regulates the fluidity of the biofilm, thereby strengthening the elastic fibers of the dermis, stabilizing the cell structure, and achieving a significant repair effect; the facial mask of the present invention can also moisturize, replenish water and Whitening effect.
Owner:FOSHAN HUIFEN COSMETICS TECH CO LTD

Therapeutic compositions and methods of treatment with capsianoside-type compounds

InactiveUS20080103102A1Safe wayBiocideNervous disorderGlycosideCompound (substance)
The present invention discloses the use of certain compounds as therapeutic agents, and in particular as analgesics and anti-inflammatory agents. Such compounds include, for example, certain diterpene monoglycosides and diterpene diglycosides. The compounds of the present invention may be synthesized or isolated from the fruit of the genus Capsicum, and in particular may be isolated from sweet bell peppers (C. annuum). Pharmaceutically-acceptable salts, enantiomers, diasteriomers, racemic mixtures, enantiomerically-enriched mixtures, solvates, and prodrugs of such compounds are also disclosed. Pharmaceutical compositions and methods of using such compounds, including pharmaceutical compositions and methods of using such compounds in combination with one or more active ingredients, are also disclosed.
Owner:BMB PATENT HLDG CORP

Method for extracting fucoidan polysaccharide sulfate

ActiveCN103980373ASolve difficult problems that are not suitable for separationSimple extraction processOrganic active ingredientsMedicineMicrobiology
The invention relates to a novel extraction method of a plant crude drug, namely a method for extracting fucoidan polysaccharide sulfate. The name of the preparation commodity is a haikun shenxi capsule. The method comprises the following main extracting steps: (1) adding 10-fold water to a dried kelp to soak for 8 hours, controlling room temperature at 8-32 DEG C, taking a soak solution to be concentrated into 1/5 of original volume for later use, and separating out alginate on the surface of a marine organism by adopting the step; (2) taking out and cutting up the soaked kelp, and homogenating by using an AH high-pressure homogenizer; (3) adding sodium hydroxide to homogenated liquid to adjust the pH value to 12, stirring for 30 minutes, standing for 12 hours, adjusting the pH value to 1.5-2 by using a hydrochloric acid, stirring for 8 hours, and standing for 12 hours; (4) filtering; (5) merging filtrate with a concentrated solution in the step (1) and desalting by adopting specific 500 electroosmosis; (6) concentrating and decoloring soup; (7) centrifuging, and washing a filter cake by using 95% ethanol; (8) drying and crushing a dry substance. The yield is improved, and the cost is reduced. Compared with the prior art, the yield of the method is improved by over 40% by detection.
Owner:吉林省辉南长龙生化药业股份有限公司

Ivermectin suspending agent, preparation method and application thereof

InactiveCN101862294AEasy to takeAccurate doseHydroxy compound active ingredientsAntiparasitic agentsMedicineBiocompatibility Testing
The invention discloses an ivermectin suspending agent, a preparation method and application thereof. Each liter of the ivermectin suspending agent is prepared from 2 to 100g of ivermectin raw material medicament, 200 to 550g of oil, 30 to 200g of emulsifier and a proper amount of water; and an auxiliary agent can be added when necessary. The ivermectin suspending agent prepared by the preparation method has the characteristics of high stability and biocompatibility and remarkable sustained-release effect, can be applied to the preparation of an ivermectin sustained-release injection, fills a domestic technology gap, and develops a new technical field for the application of ivermectin. The preparation method for the suspending agent has the characteristics of simplicity, easy implementation and low manufacturing cost.
Owner:ZHEJIANG BORNSUN MEDICINE CO LTD

Medicine for treating cold grasserie and method of preparing the medicine

ActiveCN101584809ADrug effectEffectiveComponent separationSkeletal disorderMirabilis jalapaPharmaceutical drug
The invention discloses a medicine for treating cold grasserie, comprising the raw medicine by weight parts: 50 to 150 parts of Tibet pleurospermum, 50 to 150 parts of Himalayan four-o'clock root, 50 to 150 parts of caltrop, 50 to 150 parts of Polygonati Rhizoma and 50 to 150 parts of asparagus; grain diameter of the medicine is 0.1 to 100 microns. The medicine of the invention has higher effective dissolution of medicine, medicine penetration power and bioavailability, and better medicine effect. The invention further discloses a method of preparing the medicine for treating cold grasserie and special quality examination method thereof such that the quality examination method effectively controls the stability of the medicine, and also effectively identifies the specificity of pharmaceutical ingredients in medicine.
Owner:GANSU CHEEZHENG TIBETAN MEDICINE CO LTD

Women care and nourishing beverage

The invention aims to provide a women care and nourishing beverage. The women care and nourishing beverage is prepared from the following components in parts by weight: 5-20 parts of culture of saussurea involucrate, 500-700 parts of collagen, 5-20 parts of tremella polysaccharide, 20-40 parts of lychee juice concentrate and 20-40 parts of apple juice concentrate. The culture of saussurea involucrate is warm in nature, has menstrual flow stimulating and blood activating effects, is rich in effective active ingredients such as flavone, and has anti-oxidation, immune adjustment and skin aging delay effects and the like; the collagen can provide more effective peptides and can restore the elasticity of the skin; the tremella polysaccharide has the functions of relaxing bowels, building body, reducing weight, beautifying and skin moistening functions; the lychee juice concentrate has the effects of tonifying spleen, benefiting liver, regulating vital energy and replenishing blood; the apple juice concentrate has the effects of nourishing the skin, moistening, removing freckles and removing acnes. The formula makes the focal points stand out, complements each other, helps each other forward, is rational, gives consideration to the aspects of qi nourishing, blood nourishing, beautifying and the like, and completely solves the problem of stagnation of qi and blood of women and the skin problem.
Owner:北京姿美堂生物技术股份有限公司 +1

A kind of traditional Chinese medicine composition for treating pulmonary tuberculosis

InactiveCN102258726AAntibacterial agentsPlant ingredientsWound healingLung tuberculosis
The invention discloses a traditional Chinese medicine composition for treating pulmonary tuberculosis. The components and ratios of raw materials used in the traditional Chinese medicine composition are as follows: 4-7 parts of aster, 4-7 parts of Anemarrhena, 3-6 parts of platycodon, batch 7-10 parts of leaves, 4-8 parts of Prunella vulgaris, 4-8 parts of Agrimony, 3-6 parts of Baibu, 3-6 parts of Chuanbei, 8-12 parts of Bletilla striata, 7-10 parts of L. 3-6 servings, 3-6 servings of Ophiopogon japonicus, 1.5-2.5 servings of Chonglou. The medicine of the invention has the functions of nourishing the lungs, relieving cough, reducing inflammation, sterilizing, dispelling stagnation and healing wounds, and can completely cure pulmonary tuberculosis in a short time.
Owner:白思蓉

Okra and hawthorn health care wine and preparation method thereof

InactiveCN107858230AReduce bitternessFit for drinkingDigestive systemAntinoxious agentsOfficinalisBULK ACTIVE INGREDIENT
The invention discloses an okra and hawthorn health care wine and a preparation method thereof, and relates to the technical field of heal care wines. The okra and hawthorn health care wine comprises,by weight, 32-40 parts of okra, 12-17 parts of hawthorns, 5-10 parts of tangerine peel, 7-12 parts of mangnolia officinalis, 7-12 parts of liquorice, 5-10 parts of endothelium corneum gigeriae galli,3-7 parts of radish seeds, 7-12 parts of malt, 3-7 parts of carrot, 7-12 parts of peas and 140-160 parts of sticky rice. According to the okra and hawthorn health care wine, fruits are vegetables areused as the main components, and a conventional traditional Chinese medicine alcohol extraction component is added, so that the prepared health care wine is rich in nutrient contents required by a human body, multiple kinds of active ingredients and nutrition, fragrant and mellow and has the health care efficacy of spleen strengthening, appetite promoting, digestion aiding, cancer preventing andcuring, ageing preventing and the like; after long-term drinking, the okra and hawthorn health care wine can promote bowel movement, aid digestion, prevent constipation, maintain beauty, nourish skinand improve immunity, and has the efficacy of curing gastritis and gastric ulcers and protecting gastric mucosa, so that the okra and hawthorn health care wine is suitable for drinking of all kinds ofpeople.
Owner:HEFEI LVZHILIN AGRI DEV CO LTD

Traditional Chinese medicine composition for treating endocrine dyscrasia and preparation method thereof

InactiveCN104189510APromote circulationQuick effectEndocrine system disorderPlant ingredientsSide effectSemen
The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating endocrine dyscrasia and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 20-40 parts of radix ophiopogonis, 10-30 parts of radix polygoni multiflori preparata, 15-30 parts of radix rehmanniae preparata, 10-20 parts of polygonatum odoratum, 15-25 parts of dendrobe, 10-30 parts of ligustrum lucidum ait, 10-20 parts of yams, 10-15 parts of white atractylodes rhizome, 10-20 parts of radix codonopsis, 10-15 parts of semen cuscutae, 10-15 parts of epimedium, 10-15 parts of eucommia, 10-15 parts of cistanche and 5-10 parts of liquorice. According to the traditional Chinese medicine composition for treating endocrine dyscrasia, multiple medicines are combined so as to be cooperated with one another from the medicine effect and achieve the effects of replenishing the vital essence and the blood, supplementing qi, promoting the production of body fluid and promoting blood circulation to remove blood stasis, takes a quick response, is good in treating effect and has low toxic and side effects, and the medicine property is mild.
Owner:鹿相花

Supercritical extraction method of conic gymnadenia tuber element

The invention relates to a supercritical extraction method of a conic gymnadenia tuber element, and in particular relates to a method for extracting a natural active ingredient with an anti-aging effect, i.e. the conic gymnadenia tuber element, from a Tibetan medicine conic gymnadenia tuber. According to the invention, through creating a series of new extraction process conditions of pressure, temperature, entrainer and the like and the method, the traditional extraction contradiction of active ingredient purity and extraction rate are solved. Anti-aging medicines, health care products and human hand and face skin care products, which are manufactured through taking the conic gymnadenia tuber element as a basic formula, have the characteristics of nature, safety, transdermal absorption, no side effect and the like.
Owner:SHENZHEN RAPOS LLC

Immunopotentiator and vaccine preparation for emergency vaccination of Newcastle disease

InactiveCN104069480AProduced fastEasy to operateViral antigen ingredientsPeptide/protein ingredientsBiotechnologyHemagglutinin
The invention discloses an immunopotentiator and a vaccine preparation for emergency vaccination of Newcastle disease. The active ingredient of the immunopotentiator is composed of sword bean hemagglutinin, panaxoside and astragalus polysaccharide; the vaccine preparation for emergency vaccination of Newcastle disease is composed of the immunopotentiator and Newcastle disease inactivated vaccine according to a volume ratio of 1: (5-25). After being emergently inoculated to chicken, the vaccine preparation disclosed by the invention can be used for effectively controlling the development of epidemic situation and replacing emergently inoculated virulent or attenuated vaccine, the attenuated vaccine not only brings poison and has the possibility of strong virulence return; on the other hand, the vaccine preparation can be used for compensating the defects of slow generation of antibody of the inactivated vaccine to unfavorably control the epidemic situation; meanwhile, the active ingredient of the immunopotentiator is composed of sword bean hemagglutinin, panaxoside and astragalus polysaccharide, and these extracts are active components extracted from plants, thereby meeting the requirements of environmental protection, moreover, the method is simple to operate, capable of quickly generating protective antibody, safe and effective, thereby having promotion significance.
Owner:GUANGZHOU SOUTH CHINA BIOLOGICAL MEDICINE

Method for preparing wine-flavored health-care rapeseed oil

InactiveCN103525536ASolve the problem of "green smell"Great tasteFatty-oils/fats refiningFatty-oils/fats productionPerilla oilNutrition
The invention discloses a method for preparing wine-flavored health-care rapeseed oil. The method comprises the following steps: soaking rapeseeds subjected to screening, impurity removal, cleaning, stone removal and magnetic separation in rice wine, drying and frying the seeds, rolling into a blank after frying, spraying rice wine liquid containing active ingredients of fructus forsythiae, rhizoma acori graminei, bighead atractylodes rhizome, poria cocos, radix bupleuri, cucumber stem, the seed of Chinese dodder, evening primrose, glutinous rice root, pumpkin flower and moutan bark, and steaming the blank, making cakes, stacking, pressing and refining after spraying to obtain the refined rapeseed oil; adding bunge cherry seed oil, perilla oil and pumpkin seed oil into the rapeseed oil, uniformly stirring, performing refined filtration, cooling, weighing and packaging. The rapeseed oil contains the active ingredients of multiple Chinese herbal medicines and the perilla oil and pumpkin seed oil, and nutrition and health care values of the rapeseed oil can be improved, so that the rapeseed oil has the effects of reducing swelling and eliminating stagnation, dispelling wind and heat, invigorating spleen and supplementing qi, eliminating dampness and promoting diuresis, dispelling wind and eliminating dampness and the like.
Owner:潘逸东

Method for processing fresh traditional Chinese medicines

The invention aims to provide a method for processing fresh traditional Chinese medicines. The method for processing the fresh traditional Chinese medicines comprises the following steps: A, cleaning and sorting fresh traditional Chinese medicines; B, crushing, pressing and filtering the fresh traditional Chinese medicines, thereby obtaining filtrate and decoction dregs; C, adding water into the decoction dregs, performing ultrasonic extraction for a period of time, and then pressing the decoction dregs in a presser, thereby obtaining an extracting solution; D, mixing and filtering the filtrate and the extracting solution, and then performing vacuum freeze-drying, thereby obtaining a freeze-drying product; and E, packaging the freeze-drying product. According to the method for processing the fresh traditional Chinese medicines, provided by the invention, fresh medicinal materials are directly taken as processing objects, the method has the advantages that active ingredients of fresh medicines are well preserved, the size of a finished product is small, loss of volatile components is greatly reduced, oxidization of readily oxidizable components, thermotropy of thermal sensitive components and enzymolysis degree of the active ingredients are alleviated, the defect that dried medicinal materials serving as raw materials are changed or one part of the materials are lost is overcome, and thus a basis is provided for guaranteeing the drug effect.
Owner:GUANGDONG GAOSHAN ANIMAL MEDICINE

Preparation method of sodium ibandronate

InactiveCN102898466AEasy to operateMeet the quality requirements of raw materialsGroup 5/15 element organic compoundsSkeletal disorderPhosphorous acidChlorobenzene
The invention relates to the technical field of pharmaceutical chemistry, particularly relates to a method of pharmaceutical synthesis, and specifically relates to a preparation method of sodium ibandronate. To overcome the disadvantages of high content of chlorides and phosphites in sodium ibandronate prepared by a conventional preparation method of sodium ibandronate, the preparation method of sodium ibandronate with extremely low content of chlorides and phosphites is provided. In the preparation method, 3-(N-methylpentylamino) propionic acid hydrochloride, phosphorus trichloride and phosphorous acid are employed as raw materials and reacted in a chlorobenzene solvent, so as to obtain sodium ibandronate with extremely low content of the chlorides and the phosphites. The obtained sodium ibandronate can not only meet impurity control standards of the chlorides and the phosphites in a sodium ibandronate crude drug, but also prevent low yield, long period and huge harm to human body and environment which are brought by a lot of refining steps.
Owner:JIANGSU AOSAIKANG PHARMA CO LTD

Composite fruit and vegetable composition, preparation method of composite fruit and vegetable composition, and prepared food

InactiveCN107212229ABalanced nutritional needsGood for healthDough treatmentFood ingredient functionsAdditive ingredientBULK ACTIVE INGREDIENT
The invention relates to the field of food, in particular to a composite fruit and vegetable composition, a preparation method of the composite fruit and vegetable composition, and prepared food. The composite fruit and vegetable composition comprises active ingredients and auxiliary materials, wherein the active ingredients comprise 30 to 40 parts of composite fruit and vegetable powder, 0.3 to 1 part of fruit and vegetable enzyme powder and 1 to 2 parts of konjac powder in parts by weight. The active ingredients of the composite fruit and vegetable composition provided by the invention comprise the composite fruit and vegetable powder, the fruit and vegetable enzyme powder and the konjac powder. All ingredients are matched in a cooperated way; the obtained composite fruit and vegetable composition is full-nutrition food with full nutrition; after the eating, the benefits to human bodies are realized. The preparation method of the composite fruit and vegetable composition provided by the invention has the advantages that the method is simple; the implementation is easy; each ingredient is not damaged; the active ingredients of all ingredients are remained as much as possible; the distribution of all ingredients is uniform; the large-scale production is facilitated; good foundation is provided for the popularized eating of the composite fruit and vegetable composition.
Owner:北京罗麦科技有限公司
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