74 results about "Acetic acid" patented technology

The invention discloses a method for preparing pirfenidone, comprising the following steps: subjecting 2-amino-5-methylpyridine which is a starting material to inverse diazotization and hydrolysis, extracting with extraction solvent, and recrystallizing with recrystallization solvent to obtain 2-hydroxy-5-methylpyridine; heating the 2-hydroxy-5-methylpyridine together with iodobenzene in the presence of anhydrous potassium carbonate and active copper to subject the 2-hydroxy-5-methylpyridine and the iodobenzene to nucleophilic substitution reaction to generate a target compound which is the crude pirfenidone; and recrystallizing the crude pirfenidone for one time for purification with recrystallization solvents which are ethyl acetate and anhydrous ethyl alcohol to obtain the pure pirfenidone. Compared with the prior art, the method for preparing the pirfenidone has the characteristics that: the 2-amino-5-methylpyridine which is the starting material is a commercial chemical product, is cheap and is easy to get, the inverse diazotization replaces the conventional diazotization reaction so that the operation is simple, and the purification methods of the 2-hydroxy-5-methylpyridine and the end product which is the pirfenidone are easy to operate and have high yield. The method for producing the pirfenidone consumes less energy, and the production cost is lowered due to the adoption of the method.

The invention relates to a method for separating and recovering phosphoric acid from acetic acid-nitric acid-phosphoric acid series mixed acid waste liquor. The method disclosed by the invention is characterized by comprising the following steps of: an acetic acid-nitric acid extracting step: mixing waste liquor containing acetic acid, nitric acid and phosphoric acid with an extracting agent solution of aliphatic series straight-chain saturated hydrocarbon which contains phosphoric trialkyl ester and 6-13 carbon atoms and selectively dissolving and extracting acetic acid and nitric acid from the extracting agent solution; a phosphoric acid recovering step: recovering the phosphoric acid from extracting waste liquor obtained in the extraction step; and an acetic acid-nitric acid stripping step: enabling the extracting agent solution containing the acetic acid and the nitric acid, obtained in the acetic acid-nitric acid extracting step, to be in contact with stripping water so that the acetic acid and the nitric acid are dissolved and transferred to the stripping water. The extracting agent solution is recycled by feeding the oil-phase extracting agent solution obtained in the acetic acid-nitric acid stripping step to the acetic acid-nitric acid extracting step. By means of the invention, the favorable separability of oil phase and aqueous phase in the stripping step can be maintained for a long time, and the phosphoric acid can be selectively and favorably separated and recovered from the acetic acid-nitric acid-phosphoric acid series mixed acid waste liquor for a long time with high efficiency.

The VPO catalyst is prepared with V2O2 and phosphoric acid in mixed isobutanol-benzyl alcohol solvent, and has polyglycol as dispersant. It has P / V atom rati of 1.1, specific surface area as high as 70-78 sq m / g and main material phase of vanadyl pyrophosphate. It is used the catalyst for oxidizing propane with air to preparing acrylic acid and acetic acid, and has single pass converting rate at the reaction temperature range of 380-400 deg.c of 37-72 % typically, acrylic acid selectivity of 5-35 % and total acrylic acid and acetic acid selectivity of 19-83 %. Under proper reaction condition, it has the propane converting rate of 40.3 %, acrylic acid selectivity of 33.8 %, acetic acid selectivity of 49.4 %, acrylic acid yield of 13.6 %, total acrylic acid and acetic acid yield of 33.5 % and space-time yield obviously higher than that with available similar catalyst. The preparation process of the catalyst is also disclosed.

The invention discloses a method for preparing a high-viscosity chitosan quick hemostatic patch. The method comprises the following steps: preparing chitosan gel from high-viscosity chitosan having a deacetylation degree in the range from 80% to 90%, drying the chitosan gel and then immersing one single side of the chitosan gel into a mixed solution of chloroacetic acid and isopropanol for carboxymethylation, and then soaking the chitosan gel into a 30% glycerol solution for 30 minutes and then draining; and finally, carrying out a cross-linking reaction by using a calcium chloride solution so as to introduce calcium ions and thrombin, and then carrying out vacuum freeze-drying, thereby obtaining the high-viscosity chitosan quick hemostatic patch. Raw materials used for the process of the method are low in cost; the process is simple and convenient, and short in period; the obtained chitosan hemostatic patch is high in adhesiveness, and capable of quickly stopping bleeding of a wound under the promotion effect of the calcium ions and the thrombin.

The invention discloses flexible waterproof mortar and a production method thereof. The method comprises a liquid material component and a powder material component. The liquid material component comprises styrene-acrylic emulsion, acetic acid emulsion, water, a defoaming agent, and a bactericide. The powder material component comprises quartz powder, wollastonite powder, ash concrete, a water-reducing agent, a dispersing agent, and a leveling thixotropic agent. The waterproof mortar is prepared from the liquid material and the powder material according to a ratio of 1:2. The waterproof mortar has good extensibility and high elasticity. With the mortar, slight cracks on a base layer can be resisted. During vertical surface construction, the waterproof mortar is prevented from flowing and dropping, and has good construction performance. After coating, the mortar surface is smooth as mirror. The mortar is suitable for underground space water prevention, seepage prevention, and moisture prevention. The mortar is especially suitable for water prevention of buildings with waterproof exposed underground. Soaking of underground condensed water and dew condensation to the building can be effectively resisted for a long time.

The invention discloses a method for determining methamidophos in rice wine and particularly discloses a method for detecting the content of methamidophos in rice wine by utilizing gas chromatography and liquid chromatography-tandem mass spectrometry. The method comprises the following steps: (1) extraction and purification: utilizing a solid phase extraction column to extract the methamidophos in the rice wine and using ethyl acetate to elute the methamidophos adsorbed on the solid phase extraction column; (2) preparation of matrix matched standard working solution; (3) qualitative screening and quantification by utilizing gas chromatography; (4) qualitative confirmation of positive samples by using liquid chromatography-tandem mass spectrometry; (5) blank test; and (6) result calculation and representation. The method has the following beneficial effects: the pretreatment operation is simple and practical, and the recovery rate of the methamidophos is high; and by adopting the matrix matched standard working solution, the problem of matrix effect of the methamidophos on the gas chromatograph is solved, and accurate quantification is implemented.

The invention discloses an alkylated hydrophobic MOFs material which is a Zr-based metal organic framework material subjected to acid modification and alkylation modification. The acid modification is preferably modification with acetic acid ; and the alkylation modification is modification with n-octyl trimethoxy silane. The invention also discloses an application of the alkylated hydrophobic MOFs material in preparation of cyclohexanol by cyclohexene hydration. Compared with an unmodified MOFs material, the modified MOFs material has acidic sites and certain hydrophobicity, so that the MOFs material is preferentially gathered on an oil-water interface, the emulsion stability is improved, the liquid-liquid interface area is greatly increased, and the conversion rate is further increased.

The invention discloses an application of a hydrophilic Ge-ZSM-5 molecular sieve membrane to separation of an organics / water system. The alpha-Al2O3 is taken as a carrier, the hydrophilic Ge-ZSM-5 molecular sieve membrane prepared by an in-situ hydrothermal crystallization method is adopted as a separation material, and water in the organics / water system is separated through the pervaporation effect so as to obtain the organics. When the molecular sieve membrane is applied to an ethanol-water system of 343 K, 10 to 98 wt% and an acetic acid-water system of 353 K, 30 to 98 wt%, the separating factor reaches infinity, the permeation flux reaches 2.4 kg / m2.h and 0.57 kg / m2.h, both the permeation flux and the separating factor of the membrane are kept constant in the pervaporation process of 25 h, and the membrane shows excellent stability. The application is simple and easy to operate, and the hydrophilic Ge-ZSM-5 molecular sieve membrane is suitable for industrial production.

The invention relates to a synthesis method of 2-(2-chloroethoxy) acetic acid, which belongs to the technical field of the preparation and the application of fine chemical engineering products. The invention particularly belongs to the synthesis method of 2-(2-chloroethoxy) acetic acid. The invention uses 2-chloroethoxy ethanol as starting materials, uses water as solvents, and uses nitric acid for direct oxidization to obtain products. The reaction process is shown as the accompanying drawing. The invention adopts water as the solvents, and uses the nitric acid as oxidizing agents for efficiently oxidizing the 2-chloroethoxy ethanol into corresponding acids. The method has the advantages of simple operation, low price of raw materials, easy acquisition of raw materials, simple requirement on equipment, simple after treatment and the like. In addition, the use of the organic solvent has nearly zero cost, and the invention conforms to the environmental protection industrial production requirements, so the invention has wide application prospects.

A thin-film capacitor housing heat dissipation coating is prepared from, by mass, 35 parts of resol, 3 parts of gelatin, 5 parts of glycidyl methacrylate, 3 parts of sodium dodecyl benzene sulfonate, 3 parts of gloss oil, 5 parts of dimethyl dicarbonate, 3 parts of olive oil, 3 parts of colored glaze carbylic acid, 3 parts of olive oil, 3 parts of graphene, 5 parts of pigment, 50 parts of distilled water, 3 parts of benzoyl paeoniflorin, 3 parts of sodium hypochlorite, 5 parts of a modifying agent, 3 parts of calcium carbonate, 3 parts of glacial acetic acid, 3 parts of magic acid, 5 parts of polyester resin, 3 parts of potassium dihydrogen phosphate, 1 part of sodium phosphate, 3 parts of aluminum silicate, 3 parts of imidazole, 3 parts of cohesive soil, 3 parts of polyvinyl alcohol and 3 parts of sodium borohydride. The modifying agent is added in a traditional formula to perform modification processing, the coating coated on a capacitor housing can effectively guide capacitor inside temperature rising due to work to the housing and convert heat into infrared radiation waves, and the working voltage of a capacitor can be also in a stable state in addition to prolonging of the service life of the capacitor.

The invention discloses a method for producing ethanol by recycling anaerobic digestion effluent and vinasse clear liquid and belongs to the technical fields of waste water treatment and ethanol fermentation industry. The method comprises the following steps: mixing and blending membrane filtrate obtained after membrane filtration of anaerobic digestion effluent, part of vinasse clear liquid, other material mixing water and crushed cereal raw materials, and performing processes of liquefying, saccharifying, fermenting and distilling to obtain ethanol, wherein the membrane filtrate accounts for30 to 90 percent of the total weight of the blending water, the vinasse clear liquid accounts for 10 to 40 percent of the total weight of the blending water, and the rest is other material mixing water; and the concentration of volatile acid of the blending water is controlled to be 100 to 1200 mg / L (based on acetic acid) by adjusting the proportion of the membrane filtrate, the vinasse clear liquid and other material mixing water or adding the acetic acid. By the method, discharge of ethanol production waste water is greatly reduced and water resources are saved; meanwhile, the problem thatthe ethanol is fermented to generate acid is effectively avoided, the alcohol yield is significantly increased, the utilization rate of the raw materials is increased by 1 to 5 percent, and the production energy consumption and cost of the ethanol are reduced.

The invention relates to the technical field of medicines, and particularly relates to a water-soluble hypocrellin PLGAnanoparticle and a preparation method thereof. The preparation method comprises the following steps: by taking poly(lactic-co-glycolic acid) (PLGA) as a carrier, dissolving PLGA and hypocrellin into an organic solvent to prepare an oil phase, adding into freeze-drying excipient-containing water phase under high-speed stirring, and finally obtaining the hypocrellin nanoparticle by adopting an emulsification freeze-drying method. By using a biodegradable medical polymer material PLGA used in the preparation method and approved by the food and drug administration (FDA) of the United States, the toxic and side effects of a common drug-carrying material can be reduced, the water solubility of the drug can be improved, the particle size of the prepared nanoparticle ranges from 20-200nm, the drug has red shift, the absorption of the nanoparticle in a phototherapy window (600-900nm) can be increased, and the dark toxicity of the drug can be reduced. The preparation method is simple in raw materials and easy to operate.