58 results about "Toxicity" patented technology

The invention discloses an external-use medicine for treating neck, shoulder, waist and leg diseases and osteoproliferation, and a preparation method of the medicine. The external-use medicine comprises active ingredients in parts by weight as shown in the description. The preparation method of the external-use medicine comprises the steps of wine soaking, drying, crushing, stirring, packaging and the like. The external-use medicine is completely prepared from traditional Chinese medicines and has the effects of warming channel, activating blood circulation, expelling wind, removing dampness, relieving swelling and pain, invigorating qi and blood, promoting blood circulation to remove blood stasis, tonifying kidney and strengthening du meridian. The external-use medicine has the advantages of good treatment effect, fast curative effect, very low toxicity, convenience in use and no limitation for treatment of the neck, shoulder, waist and leg diseases and the osteoproliferation. The preparation method is simple. The external-use medicine can be prepared into medicine packages which can be applied to home health care and medical treatment and are easy to carry.

PCT No. PCT/JP94/00237 Sec. 371 Date Oct. 23, 1995 Sec. 102(e) Date Oct. 23, 1995 PCT Filed Feb. 17, 1994 PCT Pub. No. WO94/19314 PCT Pub. Date Sep. 1, 1994The object of the invention is to provide a lipid device functionally equivalent to the so-called cationic liposome and of lesser toxicity and a lipid or the like as a component of the device. The compound of the invention includes but is not limited to 3-O-(4-dimethylaminobutanoyl)-1,2-O-dioleylglycerol, 3-O-(2-dimethylaminoethyl)carbamoyl-1,2-O-dioleylglycerol, 3-O-(2-diethylaminoethyl) carbamoyl-1,2-O-dioleylglycerol and 2-O-(2-diethylaminoethyl) carbamoyl-1,3-O-dioleoylglycerol. The device of the invention comprises such a lipid and a phospholipid. By administering a double-stranded RNA, for instance, together with the device of the invention, the double-stranded RNA can be safely delivered to the site of action.

The invention relates to the field of organic high-molecular compounds. In order to solve the problem of deficiency in long residual action and environment friendliness in the existing oil-based fluorine-containing low-surface-energy anti-doodling paint, the invention provides a water-based anti-doodling paint and a preparation method thereof. The preparation method comprises the following steps: adding a pigment, a filler and a dispersing agent into a toning cylinder, mixing, adding into a grinder, and grinding until the fineness is less than 20 mu m to obtain a color paste; and adding deionized water, the color paste, a fluorine-silicon-modified polyurethane core-shell emulsion, a preservative and a mildew preventive into a dispersion cylinder, mixing, sequentially adding a film forming assistant, a defoaming agent a thickener, mixing, and discharging to obtain the water-based anti-doodling paint. The film formed by the paint has the characteristics of excellent weather resistance, excellent ultraviolet resistance, excellent wear resistance, low surface energy, excellent pollution resistance, excellent doodling resistance, low VOC (volatile organic compound) emission, environment friendliness and no toxicity.

The invention relates to anti-tumor activity polypeptide and application thereof.The polypeptide has anti-tumor activity due to the fact that the polypeptide has one of the following amino acid sequences of RMKKRYPTTFVMVV and IGLKRTPMGIV, wherein Y or the second T counting from left to right in RMKKRYPTTFVMVV is modified through phosphorylation, and T in IGLKRTPMGIV is modified through phosphorylation.The polypeptide can be used for preparing an anti-tumor drug.The sequence of the polypeptide is short, and large-scale production is easily achieved; remarkable anti-tumor activity is displayed at a low dosage.The polypeptide has no toxicity to normal tissue cells and has wide application prospects.

The invention discloses a traditional Chinese medicine decoction formula for treating female acne concomitant with irregular menstruation. The traditional Chinese medicine decoction formula comprises 15g of ligusticum wallichii, 5g of fructus evodiae, 12g of angelica sinensis, 20g of unprepared coix seeds, 15g of fructus forsythia, 15g of radix paeoniae rubra, 15g of medicinal cyathula roots, 10g of silkworm excrement, 15g of scouring rush and 15g of dahurian patrinia herb. The traditional Chinese medicine decoction formula has the benefits of warming channel and expelling cold, activating blood to promote menstruation and cooling blood to remove toxicity, can be used for treating female dysmenorrheal and regular menstruation, can also be used for treating acne caused by cold attack of regulating body channels, blood stasis and stasis heat-transmission, is remarkable in treatment effect, and can radically treat symptoms such as dysmenorrheal, irregular menstruation and acne, in addition, the medicines of the formula are easy to obtain and low in price, so that the economic cost of patients can be reduced.

The invention discloses a high-sequential inorganic substance pattern and preparation method thereof, relates to surface patterning, and provides a high-sequential inorganic substance pattern and a preparation method thereof. The surface of a polymer membrane is provided with sequential porous structures which are semi-spherical circular holes evenly distributed on the surface of the polymer membrane. Distilled water is added into a container to make water vapor pressure in the container reach saturation; a polymer, a metal complex and an organic solvent are blended into a mixed solution; the mixed solution is added on a substrate, and then the substrate is put into the container filled with saturated water vapor and sealed; and after the organic solvent is completely volatilized, a porous structural membrane is obtained, and then the porous structural membrane is radiated by ultraviolet light and baked to obtain the inorganic substance pattern. The inorganic substance pattern does not need to use high temperature (over 600 DEG C), and has the characteristics of low cost and no toxicity.

The invention discloses a poultry feed additive and a preparation method thereof. The feed additive is composed of the following components in parts by weight: 20 to 50 parts of radix astragali extract, 10 to 40 parts of licorice extract, and 20 to 40 parts of fructo-oligosaccharide. The provided poultry feed additive is prepared by compounding radix astragali extract, licorice extract, and fructo-oligosaccharide, is a green feed additive, and has the characteristics of no toxicity, no residue, and no side effect. Moreover the additive is capable of improving the poultry growth performance, strengthening the poultry immunity, and improving the poultry disease resistant performance through modulating the intestinal micro environment in poultry. The preparation method of the poultry feed additive has the advantages of simple technology, convenient operation, and suitability for massive industrial production.

The invention discloses metal paint remover and a method for making the same. The metal paint remover comprises the following compositions and mixture ratio: 10 to 40 portions of methylene dichloride, 8 to 35 portions of dutch liquid, 10 to 25 portions of phenol, 5 to 15 portions of methanoic acid, 0.2 to 2 portions of octylphenol polyoxyethylene ether; the mixture ratio is in weight portion. The preparation method comprises the following steps that: firstly, methylene dichloride and dutch liquid are evenly mixed and stirred; secondly, phenol, methanoic acid and octylphenol polyoxyethylene ether are added in turn and evenly stirred to obtain a finished product. The prepared paint remover is suitable for removing various paints and has rapid paint removing speed, full removing, safe use, small toxicity, does not erode workpieces and hurt hands and can be used repeatedly and reduce environmental pollution.

The invention relates to a pesticide compound, in particular to a compound insecticide containing dinotefuran and pymetrozine. A compound insecticide containing dinotefuran and pymetrozine is characterized in that dinotefuran and pymetrozine are in a weight ratio of 1:3-1:105. Through laboratory bioassays, two compound proportions with obvious synergistic effect are screened out: when dinotefuran and pymetrozine have a content ratio of 1:7-4:175, the co-toxicity coefficient of the two are respectively at 3712.62 and 3206.61, showing extremely high level of synergistic effect. The above compound agent with reasonable ratio has strong toxicity on Hemiptera insects like brown planthopper, high co-toxicity coefficient and strong synergistic effect, and is a compound agent with high efficiency and low toxicity.

The invention discloses an ink cleaning agent with no damage to the equipment. The ink cleaning agent is characterized by comprising the following raw materials by weight: 5-7 parts of nonylphenol polyoxyethylene ether, 2-3 parts of sodium sulfonate, 1-2 parts of triethanolamine, 2-3 parts of oxalic acid, 3-4 parts of limonene, 1-2 parts of tea saponin, 1-2 parts of sodium tungstate, 2-3 parts of urotropine, 1-2 parts of sodium dichromate, 1-2 parts of sodium lauryl sulfate, 1-2 parts of sodium tripolyphosphate, 2-3 parts of castor oil, 4-5 parts of an auxiliary agent and 100-110 parts of water. The additives added in the invention improve the process performances of the cleaning agent and reduce toxic and side effects and the pollution to the environment. The ink cleaning agent provided by the invention has the advanategs of strong cleaning ability, no toxicity, no volatilization, no harm to human body, no damage or corrosion on the printing equipment, low production cost, safety, environment-friendliness and wide application prospect.

The invention relates to a making method of a high-protein fermented feed, belongs to the technical field of feed processing, and particularly relates to a making method of the high-protein fermented feed. The making method comprises the following steps of weighing a certain mass of linseed meal, adding sprouted cargo rice powder and ammonium sulfate, adding water and performing uniform mixing so as to obtain a solid culture medium; and enabling the solid culture medium to be subjected to enzymolysis, sterilization, fermentation, low temperature drying, crushing, granulation and packaging, so as to obtain finished products. The high-protein fermented feed disclosed by the invention has the advantages of being rich in nutrition, high in protein content, and good in palatability. In addition, the step of enzymolysis is performed before fermentation, so that nutrition resistant factors having toxicity in the linseed meal are decomposed and released, the eating safety is improved, nutrient substances having health-care efficacies, such as gamma-aminobutyric acid and flavonoid glycosides are also generated, and the health-care efficacies of the fermented feed are improved.

The invention relates to enrofloxacin water-soluble powder and a preparation method thereof. The water-soluble powder is prepared from the following raw materials in parts by weight: 5-20 parts of enrofloxacin and 80-95 parts of a water-soluble cyclodextrin polymer. The prepared powder can be completely dissolved into water by compounding the water-soluble cyclodextrin polymer and enrofloxacin, the bitter taste is greatly reduced and livestock ingestion is facilitated. The enrofloxacin can be absorbed by animals at the maximum extent due to its completely water soluble characteristic to achieve the optimal utilization effect. Innocuous and unpoisonous cyclodextrin derivatives which can be quickly degraded are adopted, so that a solubilizing cosolvent with toxic or side effect is avoided, and residues of toxic substances in animals are greatly reduced.

The invention discloses an organic corrosion inhibitor for inhibiting magnesium alloy corrosion and an application method of the organic corrosion inhibitor in an automobile cooling liquid or a corrosion aqueous solution. The corrosion inhibitor consists of the components in percentage by weight: 10-90 percent of pyrazine or/and piperazine and 10-90 percent of water or/and ethanol. According to the application method, the corrosion inhibitor is added into the automobile cooling liquid or the corrosion aqueous solution which immerses a magnesium alloy according to an adding amount of 50-1,000 ppm under a condition at the temperature of -50-90 DEG C. The using amount of the corrosion inhibitor disclosed by the invention is small; the corrosion inhibitor is high in corrosion inhibition efficiency and good in corrosion inhibition effect; under normal temperature, the corrosion inhibition rate can be over 90 percent. The corrosion inhibitor is organic, so that the common shortcomings of an inorganic corrosion inhibitor are overcome; the application temperature range is wide; the organic corrosion inhibitor is applicable to low temperature and normal temperature and can still effectively inhibit corrosion of the magnesium alloy in a solution medium with higher temperature, and the corrosion inhibition rate can be over 80 percent under the higher temperature. The corrosion inhibitor product disclosed by the invention has the advantages of simplicity in production, wide application range, no toxicity, no peculiar smell, complete water solubility, safety and convenience in operation, good economical property and the like.

The present invention provides a rheumatism plaster, a thread-gluing breathable bag for packing rheumatism plaster and a production method thereof. The rheumatism plaster includes the following raw materials such as dried pinellia tuber, dried bile arisaema, dried szechuan aconite, dried kusezoff monkshood root, dried nux vomica, sesame oil and yellow lead. The rheumatism plaster is obtained through the following method: a required amount of sesame oil is boiled; then a required amount of dried pinellia tuber, dried bile arisaema, dried szechuan aconite, dried kusezoff monkshood root and dried nux vomica are mixed, poured into boiling sesame oil and fried with mild fire until the drug turns black and carbonized; herb residues are removed after fire is extinguished and a required amount of yellow lead is poured and evenly mixed after the sesame oil cools without boiling. The present invention adopts high-temperature sesame oil to make decoction of the five drugs, so that the toxicity disappears without decreasing the pharmacodynamical effect. The pharmacodynamical ingredients can be fully fried out; in addition, the quality of sesame oil is sticky, the sesame oil gradually dilutes in normal temperature of human body, the pharmacodynamical effect gradually releases and the plaster does not infiltrates the gauze and attach on the skin, so that the present invention achieves the aim of curing rheumatism without allergy. Besides, the present invention also has simple structure and convenient use.

The invention relates to a composition with effect of treating gout. The composition is characterized by consisting of the following ingredients in percentage by weight: 20 to 30 percent of codonopsis alpina, 20 to 30 percent of tinospora sinensis merr, 12 to 20 percent of costustoot, 12 to 20 percent of nardostachyos root and rhizome and 12 to 20 percent of northern corydalis bungeana. The composition of the invention has the effects of clearing heat and releasing toxin, eliminating swelling and stopping pain, and dispelling wind and removing dampness. The composition is mainly used for treating gout. The composition overcomes the defects that the symptoms can be cured, the root cause cannot be cured, the medicament has high toxicity, the disease is susceptible to relapse after treatment, and the total effect of the treatment is not good enough in the conventional treating method.

The invention discloses an application of isoflavone which has substituent in the two intermediate rings and is taken as an animal feed additive, an animal oral dose or an animal water mixture agent. The isoflavone which has substituent in the two intermediate rings is taken as the animal feed additive used in the feed of animals such as pig, poultry, aquatic livestock, ruminant, and the like, thus promoting animal growth and improving feed utilization, animal immunity and reproductive property. The isoflavone can be used for replacing antibiotics used in feed or other feed additives which promote animal growth so as to eliminate the antibiotic residue in cultured animal products, to produce safe cultured animal products with good quality and reduce feed or culture cost. The isoflavone has high biological activity, stable quality, low use cost, no residue, no toxicity, no mutagenesis, carcinogenesis or teratogenesis, so the isoflavone is a green, safe, high efficient and environment-friendly feed additive.

The invention relates to a method for establishing an animal model for senile dementia, a special liquid medicine and a dosing device, and belongs to the technical field of neurosciences. The method comprises the following steps: obtaining positioning coordinates of paraceles according to brain atlases or/and magnetic resonance image data of an experimental animal; respectively burying a conduit of the dosing device in left and right paraceles of the animal, and injecting the special liquid medicine to the paraceles at a constant speed in 14-16 minutes under a sterile environment within 2-3 weeks, wherein the liquid medicine amount is 100-250 ml methanol per day; alternately dosing the left and right paraceles, wherein the dosing frequency is 18-30 hours at an interval; and continuously dosing for 2-10 months to obtain a non-human primate animal model for senile dementia. With the adoption of a novel dosing mode: dosing to the paraceles at the constant speed, medicine can circulate to whole brain through the cerebrospinal fluid to exert the toxic effect, so that peripheral damage by the medicine is avoided. The AD model is established by injecting methanol or formaldehyde to the paraceles, so that behaviors and pathological symptoms are typical, the basic physiological status is good and the individual difference is relatively smaller.

The invention discloses a lung caring pill, belonging to traditional Chinese medicine preparations. The lung caring pill comprises the following active pharmaceutical ingredients in certain parts by weight: bulbus fritilariae, almond, pseudo-ginseng, lumbricus amd ephedra. The lung caring pill is used for treating bronchitis and chronic bronchitis, and the effective rate for preventing pulmonary fibrosis is up to 91.2%; and the toxicity test and clinical practice prove that the medicine is safe and effective and has no toxic or side effect. The medicine can have the effects of moistening the lung, resolving the phlegm, promoting the dispersing function of the lung, regulating the flow of qi and relieving cough and asthma. The lung caring pill does not have a therapeutic action on the formed fibrosis pathological changes, but can reinforce the blood flow of the partial capillary network, improve the pulmonary alveolus function, promote the extinction of the bronchus chronic inflammation, decrease the inflammatory exudation and prevent pulmonary fibrosis from further development. The lung caring pill has the characteristics of definite curative effect, high safety and high economical performance.

The invention relates to a degradable capacitor plastic shell which is composed of the following components in parts by weight: 35 parts of polyvinyl alcohol resin, 15 parts of gelatin, 10 parts of methyl-silicone rubber, 5 parts of hyaluronic acid, 5 parts of tribasic lead sulfate, 5 parts of nano silicon dioxide, 5 parts of modified wood-plastic powder, 2 parts of chlorinated paraffin, 2 parts of propanediol, 2 parts of palm oil, 5 parts of carbon fiber, 5 parts of metallocene polyethylene, 2 parts of methylsilicone oil, 0.5 part of tobacco cellulose, 2 parts of plasticizer, 2 parts of oxidized polyethylene, 2 parts of dioctyl adipate, 2 parts of rare-earth light conversion agent, 2 parts of cotton fiber, 2 parts of corn starch, 2 parts of polyester rubber powder, 2 parts of butyl acetate and 2 parts of talcum powder. The method has the advantages of simple components and low cost; the finished product is degradable, has stable performance, and does not have toxicity or harm in a high-temperature environment; and meanwhile, by changing the traditional preparation technique and adding the refrigeration procedure, the product has higher safety and still has favorable stability at higher temperature.

The invention relates to an oxidative degradation method for cyanide in cyaniding tailings. The oxidative degradation method comprises the steps that the mass percentage of the water content of the cyaniding tailings obtained after filter pressing is controlled to be 20-30%, stirring is conducted, and three or more of cement, aluminum powder, sulphur powder, sodium perborate and sodium chloride are added, wherein the amount of added chemicals accounts for 2.2-7.7% of the dry weight mass percent of the cyaniding tailings; a trolley is loaded with the materials and then put into a high-pressurereaction still, and after vacuum extraction is conducted on the materials in the high-pressure reaction still, steam is introduced; and after the temperature is raised to 180-200 DEG C, the pressure is maintained for 4.5-10 hours, depressurization is conducted so that the ammonia-containing steam is exhausted, and the residual cyaniding tailings in the high-pressure reaction still can be convertedinto another type of ordinary solid waste through hazardous waste toxicity identification. The degradation method is good in cyanogen removal effect; cyanogen removal is irrelevant with the initial concentration of cyanogen and is relevant with the time and temperature; the cyaniding tailings obtained after treatment can meet the environment protection requirement and be directly reused as a secondary resource; and by means of hazardous waste toxicity leaching identification, the PH value is 7-9, and the density of the total cyanide is 2 mg/L.

The invention discloses a polyvinyl acetate polymerization method, which uses dimethyl azobisisobutyrate as an initiator to initiate polymerization. The initiator has the advantages of safety, non-toxicity, stable performance, stable decomposition rate, and high initiation efficiency. The PVAC produced has narrow distribution, good quality, high conversion rate, and no residue and agglomeration.

The invention discloses nutritional food for treating constipation and reducing internal fat and a preparation method thereof, and belongs to the technical field of health-care food. The nutritional food for treating constipation and reducing internal fat disclosed by the invention is mainly prepared from the following components: noni fruit enzyme powder, passion fruit enzyme powder, pomegranate enzyme powder, mangosteen enzyme powder, blueberry enzyme powder, amorphophallus albus gum, soybean dietary fiber powder, oat fiber powder, apple fiber powder, fructooligosaccharide and strawberry fruit powder, wherein the passion fruit enzyme powder accounts for 5 parts by weight, the pomegranate enzyme powder accounts for 5 parts by weight, the mangosteen enzyme powder accounts for 5 parts by weight, the blueberry enzyme powder accounts for 10 parts by weight, the amorphophallus albus gum accounts for 10 parts by weight, the soybean dietary fiber powder accounts for 5 parts by weight, the oat fiber powder accounts for 10 parts by weight, and the apple fiber powder accounts for 5 parts by weight. The nutritional food can clear away the toxicity of intestines and eliminate overnight excrement if the nutritional food is eaten for a long time, and has the effects of relieving the bowel, relieving the constipation, tightening up the belly and beautifying the skin, and removing the toxicity; moreover, the nutritional food also can maintain beauty and keep young, and the skin problems such as formation of color spots, acnes and the like can be effectively prevented.

The invention discloses syrup capable of relieving a cough and reducing sputum, and relates to the technical field of foods. The syrup is prepared from the following raw materials in parts by weight: 5-10 parts of coastal glehnia roots, 5-10 parts of solomonseal rhizomes, 4-8 parts of lily bulbs, 4-8 parts of white funguses, 2-4 parts of licorice roots, 3-6 parts of dried orange peel, 10-20 parts of apple juice, 100-200 parts of maltose and 50-100 parts of clean water. The syrup capable of relieving the cough and reducing sputum disclosed by the invention has the efficacies of moistening the lung for relieving a cough, benefitting the stomach, promoting salivation, clearing the lung for reducing sputum, clearing heat and removing toxicity, and after the syrup is often eaten, the effects of promoting blood circulation, being health-care and resisting ageing are also achieved.