56 results about "Nanoparticle" patented technology

RO membranes using chlorinated water as a feed stream maybe protected from damage by the chlorine with a protective layer including reactive nitrogen which forms chloromines on the surface of the membrane that reduce chlorine penetration. This protective layer also provides substantial anti-fouling capabilities, whether used with a chlorinated or unchlorinated feed stream because the chloramines are anti-bacterial. Although chlorine is lost in use, the anti-fouling layer or coating can be recharged with additional chlorine without damaging the discrimination layer. The anti-fouling layer or coating may be advantageously used with Thin film composite, TFC, membranes for use in forward and reverse osmosis may include nanoparticles, monohydrolyzed and/or di-hydrolyzed TMC, and/or alkaline earth alkaline metal complexes or other additives.

The Body Cavity Cancer Treatment Apparatus generates the magnetic field for use in a combined “Low Temperature Hyperthermia” and ionizing radiation and/or chemotherapy cancer treatment protocol. Unlike other competing systems, the Body Cavity Cancer Treatment Apparatus does not directly kill or ablate the cancer cells with killing temperatures rather, the Body Cavity Cancer Treatment Apparatus stresses the cancer and cancer stem cells by keeping them at a nominal 42° Celsius for some period of time via the heating of nano-particles that have been infused into the bladder, using the generated magnetic field.

An electrode comprises a conductor and an electrode coating, said electrode coating comprising as electronically active material a transition metal (T) oxidenitride of formula Li_xT^I_mT^II_nN_yO_z form of nanoparticles, wherein x=0-3, y+z=2-4, y>0, z>=0.25, m+n=1, m=0-1, n=0-1, T^I and T^II both being transition metals of the groups IVB, VB, VIB and VIIB, and periods 3d, 4d and 5d, in particular transition metals selected from Zr, Nb, Mo, Ti, V, Cr, W, Mn, Ni, Co, Fe and Cu. Dependent on the kind of transition metal, its oxidation state and the Li content, such materials may be used as anode materials or as cathode materials, respectively.

The invention relates to a gold-core-composite nano-carrier as well as a preparation method and application thereof. According to the gold-core-composite nano-carrier, a silicon dioxide modified gold nanorod (Au@SiO2) is taken as an inner core and is coated with a layer of high polymer material sensitive to temperature and pH. The gold-core-composite nano-carrier can be used for coating various drug and probe molecules and transporting the drug and probe molecules to disease sites, and therefore, the targeted therapy is realized. After absorbing near-infrared laser, the gold-core-composite nano-carrier or a drug-loading nanoparticle can emit fluorescent light, and partial optical energy can be converted into heat to be applied to biological imaging, chemotherapy and thermal therapy; the gold-core-composite nano-carrier further has the pH-sensitive property and is capable of effectively releasing the drug molecules in a weakly acidic tumor microenvironment and cell lysosome; multiple tumor therapy functions of the gold-core-composite nano-carrier can be combined in use, so that the defects of a single tumor therapy method are overcome; the gold-core-composite nano-carrier is suitable for being applied to the complex tumor diagnosis and treatment.

The invention discloses porous zinc oxide nano powder and a preparation method thereof. The method comprises the following steps: firstly, zinc nitrate hexahydrate is dissolved in anhydrous ethanol or deionized water, added with PEG 400 under the condition of magnetic stirring and uniformly mixed; secondly, ammonium bicarbonate is dissolved in the deionized water or the anhydrous ethanol; thirdly, the mol ratio of the zinc nitrate to the ammonium bicarbonate is 1 to 2.5, and a zinc nitrate ethanol solution or a zinc nitrate water solution is dripped into the deionized water and/or an anhydrous ethanol solution of the ammonium bicarbonate, and then precursor is obtained; fourthly, the precursor is washed by an ammonium bicarbonate water solution after centrifugal separation, washed by the anhydrous ethanol, dried, added with n-butylalcohol, uniformly dispersed and then refluxed for 1 to 2 hours at a temperature of between 115 and 120 DEG C, the n-butylalcohol is recovered by vacuum distillation, and the porous zinc oxide nano powder is prepared by utilization of afterheat to dry solid by distillation. The particle diameter of the porous zinc oxide nano powder is between 10 and 250 nanometers; the inside of a nano particle has a porous structure; and the aperture of an inner hole of the particle is between 5 and 120 nanometers.

A preparation method of high-strength cast aluminum alloy is characterized in that the cast aluminum alloy comprises the following components: Al, Zn, Ni, Mg, Cu, Mn, Cr and the like; the method comprises the following steps: configuration and melting of alloy; rotary injection treatment; adding of nano-scale ceramic particles; ultrasonic treatment; melt casting; solution treatment; aging treatment. Compared with the prior art, the preparation method has the advantages that the prepared high-strength cast aluminum alloy is uniform in microstructure, and excellent in combination of strength and toughness; due to the adoption of nano-particle modification and power ultrasound treatment, the problems of thick second solidification phase and non-uniform distribution in aluminum alloy casting are solved.

The present invention relates to formulations comprising aluminum nitride nanoparticles, at least one dispersant and at least one aqueous solvent, to the method for obtaining said formulations as well as to their use for obtaining a leveling barrier layer.

The invention provides a polyethylene glycol-polyamide-amine-polyamino acid linear-dendritic block polymer with a structure shown as a formula I, II, III or IV. The polyethylene glycol in the block polymer can be used for improving the biocompatibility of the block polymer and prolonging the circulation time of the block polymer in the blood, and a polyamino acid block can be used for ensuring the favorable degradation performance of a product and can be discharged in vitro after being degraded in vivo. The block polymer provided by the invention is simple in preparation method and safe and nontoxic in product. The block polymer is used as a carrier and assembled in water to form nanoparticles, and a model drug adriamycin is carried, so that drug-carried nanoparticles are obtained, and the drug-carried nanoparticles have a certain controlled-release function and can be used for effectively inhibiting the proliferation of cancer cells in cell experiments. Therefore, the block polymer has the potential application as a nano-drug carrier.

The invention relates to the technical field of biosensor, in particular to a fluorescence biosensor based on amplification of a hybridization chain reaction. The problems that the specificity and sensitivity of the method for detecting the kanamycin is low, and the cost is high in the above prior art are solved. According to the fluorescence biosensor based on the amplification of the hybridization chain reaction, the cyclic amplification effect is achieved through the hybridization chain reaction between the endonuclease IV and the chain. The mixture is reacted homogeneously by fluorescenceresonance energy transfer of the fluorophores and the quenching group. The preparation method comprises the following steps of: preparing gold nanoparticles; modifying Walker and Track to the surfaceof gold nanoparticles; mixing the labeled gold nano solution with the homogeneous reaction solution; performing hybridization chain reaction, and detecting the fluorescence; using the specific recognition of the nucleic acid Aptamer, using the nucleic acid Aptamer for high specific detection of the target kanamycin; and using the amplification of the hybridization chain reaction to achieve signalamplification.

A series of amphiphilic polymer materials which take pulullan as a main chain and polyester as a branch chain are synthesized. By adopting a novel synthetic method, the synthetic time of the series of amphiphilic polymer materials is shortened to 5 minutes, so that the materials have a relatively high industrial value. The series of amphiphilic polymer materials have multi-aspect application values in the field of medicine transfer such as microsphere and nanoparticle reparations and the like as well as modification of other medicine transfer systems and the like. The series of amphiphilic polymer materials are used for preparing nanoparticles and microsphere conveying transfer medicine or modification medicine transfer carriers such as nanoparticles and microspheres so as to achieve the purpose of increasing the solubility and stability of medicines, improving the curative effect of the medicines and reducing the toxic and side effects of the medicines. The series of materials, which are used as the medicine transfer carriers or modification medicine transfer carriers, can be used for achieving the purpose of liver targeting delivery and temperature sensitive control released delivery at the same time.

Methods and devices for microfluidic detection of a biological maker in a biospecimen collected from a subject are disclosed. The microfluidic devices include nanoparticle-based nanosensors comprising supramolecular recognition sequences, protease consensus sequences, post-translationally modifiable sequences, or sterically hindered benzylether bonds for specific interaction with a biological marker. Also disclosed are particular nanosensors for detecting cytokines, and other proteins based upon supramolecular recognition without chemical modification or enzymatic cleavage.

The invention discloses a preparation method of an oxide nanocrystal solid. According to the method of the invention, a soluble high valence metal cation is hydrolyzed, while a metal oxide anion is not hydrolyzed but taken as a protective agent to form a metal oxide nanocrystal, and then self-assembly is performed to form a three-dimensional nanocrystal solid with nanocrystal particles in ordered arrangement. The preparation method of the oxide nanocrystal solid of the invention is an inexpensive, simplified, non-toxic and pollution-free method, which hydrolyzes the metal cation into oxide nanoparticles that are then assembled into a novel photoelectric material with a three-dimensional ordered structure. As the method of the invention employs pure inorganic substances for reaction, the product has substantially improved electroconductive performance, and a special photoelectric performance is generated.

The invention relates to the field of biological chemistry and particularly relates to a rapid bacterium detection method. The detection method comprises the following steps: mixing a detecting sample, Cu<2+>, alkynyl and AuNPs functionalized by azide group, incubating, and observing the change of the solution color to obtain the bacterium concentration. According to the detection method provided by the invention, the specificity is strong, and the sensitivity is high, and the bacterium detection technology established by the invention has the advantages of rapidness, simplicity in operation and visible result compared with a bacteria culture method and a PCR method.

The invention relates to the technical field of photothermal nanomaterials, particularly tumor-targeting nanoparticles, a preparation method and application thereof, the tumor targeting nanoparticleshave a spherical shell-core structure, comprises a PFOB core and an IR780 core liposome membrane surrounding the PFOB core, wherein the IR780 core liposome membrane comprises a liposome layer and IR780 iodide particles, and the tumor-targeting nanoparticles have a particle size range of 220 to 320 nm. The potential of the tumor targeting nanoparticles is-28.32- -19.48 mV, drug loading 3.87%-4.87%and encapsulation efficiency 85.7%-87.9%. The invention provides a tumor-targeting nanoparticle, preparation method and application thereof, which can evaluate tumor by preoperative photoacoustic imaging, CT imaging and near-infrared fluorescence imaging, optimize tumor resection under the guidance of intraoperative near-infrared fluorescence, and kill residual focus by auxiliary photothermal treatment during operation.

The invention discloses an inorganic sensitive layer based surface enhanced Raman spectrum detection technology and material preparation thereof. According to the detection technology, a surface enhanced Raman spectrum material based on an inorganic sensitive layer is used as an active substrate of a surface enhanced Raman scattering, and is exposed in the small molecule atmosphere; a new solid substance formed by specific reaction of the inorganic sensitive layer and small molecules to be detected by a Raman spectrometer is detected, and the type of the small molecules is obtained according to the Raman spectrum of the new solid substance; according to the preparation method, a colloid electrostatic self-assembly method, a thiourea-induced isotropic shell growth method, a metal halogenation method and a physical deposition method are used for a precious metal nanoparticle colloidal solution, a metal salt solution and a thiourea solution to prepare the material in which precious metalnanoparticles are coated with a metal oxide layer, or the precious metal nanoparticles are coated with a metal sulfide layer, or the precious metal nanoparticles are coated with a metal halide layer.The technology can be used for real-time online detection of hydrogen sulfide, carbon disulfide, hydrogen chloride, mustard gas, nitrogen dioxide and the like.

The invention relates to a preparation method of perovskite structure lead titanate single crystal nanoparticles. The method adopts hydrothermal reaction and subsequent high-temperature calcination, a mixed precipitate of titanium and lead ions introduces reactant material of hydrothermal reaction, a potassium hydroxide mineralizer promotes partial crystallization of a product to form precursor powder, then the precursor powder is completely crystallized in a subsequent high-temperature calcination process, therefore, synthesis of perovskite structure lead titanate single crystal nanoparticles is realized. The method provided by the invention has characteristics of simple process, easy control, no pollution and low cost, and is easy for large-scale production. The prepared perovskite structure lead titanate single crystal nanoparticles have high purity, good dispersity, and uniform size.

The invention discloses a photosensitive chitosan derivative/precious metal nanoparticle/carbon material composite functional coating layer and a production method thereof. The method comprises the following steps: synthesizing a photosensitive chitosan derivative; and preparing a carbon material/nanometer gold, silver and platinum composite material by adopting the photosensitive chitosan derivative as a bridge, processing the composite material to prepare a solution, and producing the functional coating layer on an electrode, glass, an iron plate, an aluminum plate and other base materials. The photosensitive chitosan/carbon material/precious metal nanoparticle composite material prepared in the invention can form a uniform and stable dispersion liquid, the production method has the characteristics of simple operation, easy control and mild reaction conditions, and the coating layer produced by using the composite material has good biocompatibility, conductivity and bacterialness, and can be applied to the field of sensors.

The invention discloses a monometal-loaded ruthenium charcoal catalyst, a preparation method therefor and an application of the monometal-loaded ruthenium charcoal catalyst. The catalyst is prepared from a support, i.e., activated charcoal and an active ingredient, i.e., ruthenium nanoparticles, wherein the ruthenium nanoparticles have a particle size of 2nm to 5nm, and the loaded amount of ruthenium is 5wt% to 15wt%. According to the catalyst, the activated charcoal serves as the support, and the support is cheap and readily available. The prepared loaded ruthenium monometal catalyst has theadvantages of simple preparation process, high catalytic activity, good stability and the like and can achieve hydrogenation of trimellitic anhydride in a water phase at a relatively low temperature of 100 DEG C to 150 DEG C under a relatively low pressure of 4.0 MPa H2 to complete the preparation of cyclohexane trimethyl anhydride; and the cost is low, the conversion ratio and selectivity are high, the process is simple, the solvent employed is water, and thus, the method is in line with rules of green chemistry.

The invention belongs to the technical field of photoelectric materials, and specifically relates to a hole transport material, a QLED (Quantum dot Light-Emitting Diode) device and a preparation method thereof. The hole transport material comprises p-type metal oxide nanoparticles and graphdiyne dispersed in the p-type metal oxide nanoparticles. The material of a hole transport layer of the QLED device includes the hole transport material. By adding the graphdiyne with high hole mobility into the hole transport layer and by virtue of the excellent hole migration ability of the doped graphdiyne, the hole separation ability and hole migration ability of the hole transport layer in the QLED can be significantly improved, the work function of the film material is adjusted, the hole transport efficiency of the device is improved, and the effects of improving the transport and light emitting-emitting efficiency of the device and prolonging the life of the device are achieved.

The invention discloses a preparation method of a paper-based photocathode biosensor for detecting microRNA. A gold nano-particle layer is coated in a working area of a paper-based carbon working electrode; polyhedral cuprous oxide is electrodeposited and lots of silver sulfide quantum dots can be loaded, and a photoelectric sensitized structure is formed, so that the cathode photocurrent is increased substantially; and in the presence of the target microRNA, a double-strand-specific-nuclease-induced target cycle reaction and a cascaded stem-branch hybridization strand reaction are made to obtain a negatively charged dendritic DNA double-helix structure. After assembling of positively charged gold nanoparticles, a gold tree with the good glucose oxidase mimicking activity is formed, so that the glucose oxidation reaction is catalyzed, the dissolved oxygen of the electron acceptor is consumed, the cathode photocurrent signal is reduced, and sensitive detection of the microRNA is realized.

The present invention relates to nanoparticles for encapsulating compounds, the preparation and uses thereof, comprising a casein matrix, a basic amino acid and a metal selected from a divalent metal, a trivalent metal and combinations thereof. Said nanoparticles can encapsulate a water soluble or fat soluble biologically active compound. The invention is applicable in the food, pharmaceutical and cosmetic sectors and in the nanotechnology sector.

The invention discloses a synthesis method of EPS-RB nanometer particles for photodynamic bacterium resistance. Lactobacillus plantarum exopolysaccharides EPS, rose-bengal RB, 1-(3-dimethylaminopropyl)-3-ethylenediamine hydrochloride EDC-HCl and N-hydroxysuccinimide NHS are used as raw materials; reaction is performed in dimethyl sulfoxide DMSO to obtain compounds EPS-RB; the compounds EPS-RB aresubjected to self assembly to form spherical nanometer particles in a water solution; a good photodynamic bacterium resistance effect is achieved. The compound can realize the self aggregation in thesolution to form nanometer particles; the nanometer particles generates singlet oxygen higher than free RB under the light illumination condition, so that the photodynamic bacterium resistance on escherichia coli and staphylococcus aureus is superior to that of the free RB. The concentration required by EPS-RB nanometer particles for completely killing escherichia coli and staphylococcus aureus isrespectively 8mu M and 500nM; the concentration required by the free RB is respectively 16 mu M and 1000nM.

The present invention relates to a method for treatment of semiconducting nanoparticles wherein in a step A semiconducting nanoparticles comprising long chain insulting primary ligands are dispersed in a volatile dispersion solvent capable of dissolving insulating primary ligands and precipitated using a washing agent. TGA-MS analysis shows that the treatment according to the method of the present invention allows complete removal of the outer layer of synthesis ligands of the surface of prepared nanoparticles and improves removal of synthesis ligands on the surface of prepared nanoparticles. The present invention also relates to semiconducting nanoparticles, ink formulation and electronic devices comprising the semiconducting nanoparticles obtainable by the procedure of the invention.