Inorganic sensitive layer based surface enhanced Raman spectrum detection technology and material preparation thereof

[0047] The concrete steps of preparation are:

[0048] First, according to the volume ratio of 0.5mol / L noble metal nanoparticle colloidal solution and 0.1mol / L metal salt solution is 0.5:1, add the metal salt solution dropwise to the noble metal nanoparticle colloidal solution, and let it stand for 10 minutes; Wherein, the noble metal nanoparticle colloidal solution is a gold nanoparticle colloidal solution, and the metal salt solution is an aqueous copper chloride solution to obtain a mixed solution. Carry out centrifugal cleaning to mixed solution again; Wherein, centrifugal cleaning is to use ethanol and water respectively centrifugal cleaning 3 times, the rotational speed during the centrifugation in centrifugal cleaning is 8000r / min, the time is 6min, obtains the surface covered with metal hydroxide of noble metal nanoparticles. Next, according to the weight ratio of noble metal nanoparticles coated with metal hydroxide on the surface and pure water at a weight ratio

[0056] The concrete steps of preparation are:

[0057] First, according to the volume ratio of 0.5mol / L noble metal nanoparticle colloidal solution and 0.1mol / L metal salt solution is 1:1, add the metal salt solution dropwise to the noble metal nanoparticle colloidal solution, and let it stand for 11 minutes; Wherein, the noble metal nanoparticle colloidal solution is a gold nanoparticle colloidal solution, and the metal salt solution is an aqueous copper chloride solution to obtain a mixed solution. Carry out centrifugal cleaning to mixed solution again; Wherein, centrifugal cleaning is to use ethanol and water each centrifugal cleaning 3 times respectively, the rotating speed during the centrifugation in the centrifugal cleaning is 8500r / min, the time is 5min, obtains that the surface is covered with metal hydroxide of noble metal nanoparticles. Next, according to the weight ratio of noble metal nanoparticles coated with metal hydroxide on the surface and pure water at a

[0065] The concrete steps of preparation are:

[0066] First, according to the volume ratio of 0.5mol / L noble metal nanoparticle colloidal solution and 0.1mol / L metal salt solution is 2.5:1, add the metal salt solution dropwise into the noble metal nanoparticle colloidal solution, and let it stand for 12 minutes; Wherein, the noble metal nanoparticle colloidal solution is a gold nanoparticle colloidal solution, and the metal salt solution is an aqueous copper chloride solution to obtain a mixed solution. Carry out centrifugal cleaning to mixed solution again; Wherein, centrifugal cleaning is to use ethanol and water each centrifugal cleaning 3 times respectively, the rotating speed during the centrifugation in the centrifugal cleaning is 9000r / min, the time is 4min, obtains that the surface is covered with metal hydroxide of noble metal nanoparticles. Next, according to the weight ratio of noble metal nanoparticles coated with metal hydroxide on the surface and pure water