Immunopotentiator and vaccine preparation for emergency vaccination of Newcastle disease

An immune enhancer, the technology of chicken Newcastle disease, applied in the field of poultry biological product cultivation, can solve the problems of slow antibody production, affecting egg production rate, permanent poisoning, etc., and achieve the effect of reducing impact, reducing mortality, and simple operation.

Inactive Publication Date: 2014-10-01
GUANGZHOU SOUTH CHINA BIOLOGICAL MEDICINE
View PDF1 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technology describes how new types of virus called Chikungunya (CHIKV), caused severe outbreaks worldwide have been identified through researchers studying wild birds around them during their migration across international borders. They found these diseases were associated with CHIKV's ability to infect humans causing serious illnesses such as dengue fever, yellow fevers, bubonic plague, etc., making this discovery possible. By mixing certain substances into live-vaporized influenza vims containing CHI V proteins, scientists discovered that they could help stop further spreading harmful strains like HIV-1. Additionally, when used together with another type of virus known as SARS CoV-2, some symptoms may be reduced but still being fatal if combined with both fluids. Overall, this innovative approach allows us to develop better ways to prevent future pandemics while also minimizing damage to our crops due to exposure to unknown pathogens.

Problems solved by technology

This patented technical problem addressed in this patents relates to new castle syndrome that causes severe damage to avian species like swimming cows and goats during their period between two seasons when there were no natural exposure from other animals beforehand. Current methods involve developing an antiinflammatory agent against these harmful organisms which could lead to future outbreaks even after several months' passage through international borders.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Immunopotentiator and vaccine preparation for emergency vaccination of Newcastle disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiment 1: the preparation of immunopotentiator

[0033] The main components of the immunoenhancing preparation are concanavalin, ginsenoside, and astragalus polysaccharide, and its preparation method is as follows:

[0034] Mix 25mg of concanavalin, 80mg of ginsenoside, 110mg of astragalus polysaccharide with 0.1mol / L sodium citrate solution, and fully dissolve, so that the concentrations of concanavalin, ginsenoside and astragalus polysaccharide are respectively 0.25mg / ml , 0.8mg / ml, and 1.1mg / ml are immune enhancement preparations. The prepared immune enhancer was quantitatively divided into 10ml / bottles and stored at 4°C.

Embodiment 2

[0035] Embodiment 2: the preparation of immunopotentiator

[0036] Mix 15 mg of concanavalin, 60 mg of ginsenoside, and 80 mg of astragalus polysaccharide with sterilized phosphate buffer, and dissolve them fully so that the concentrations of concanavalin, ginsenoside, and astragalus polysaccharide are 0.15 mg / ml and 0.6 mg / ml, respectively. mg / ml, 0.8mg / ml are immune enhancement preparations. The prepared immune enhancer was quantitatively divided into 10ml / bottles and stored at 4°C.

Embodiment 3

[0037] Embodiment 3: the preparation of immunopotentiator

[0038] Mix 40 mg of concanavalin, 100 mg of ginsenoside, and 150 mg of astragalus polysaccharide with sterilized purified water, and dissolve them fully so that the concentrations of concanavalin, ginsenoside, and astragalus polysaccharide are 0.4 mg / ml and 1 mg / ml respectively , 1.5mg / ml, which is the immune enhancement preparation. The prepared immune enhancer was quantitatively divided into 10ml / bottles and stored at 4°C.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses an immunopotentiator and a vaccine preparation for emergency vaccination of Newcastle disease. The active ingredient of the immunopotentiator is composed of sword bean hemagglutinin, panaxoside and astragalus polysaccharide; the vaccine preparation for emergency vaccination of Newcastle disease is composed of the immunopotentiator and Newcastle disease inactivated vaccine according to a volume ratio of 1: (5-25). After being emergently inoculated to chicken, the vaccine preparation disclosed by the invention can be used for effectively controlling the development of epidemic situation and replacing emergently inoculated virulent or attenuated vaccine, the attenuated vaccine not only brings poison and has the possibility of strong virulence return; on the other hand, the vaccine preparation can be used for compensating the defects of slow generation of antibody of the inactivated vaccine to unfavorably control the epidemic situation; meanwhile, the active ingredient of the immunopotentiator is composed of sword bean hemagglutinin, panaxoside and astragalus polysaccharide, and these extracts are active components extracted from plants, thereby meeting the requirements of environmental protection, moreover, the method is simple to operate, capable of quickly generating protective antibody, safe and effective, thereby having promotion significance.

Description

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Owner GUANGZHOU SOUTH CHINA BIOLOGICAL MEDICINE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap