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8 results about "Dermis" patented technology

The dermis or corium is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, that primarily consists of dense irregular connective tissue and cushions the body from stress and strain. It is divided into two layers, the superficial area adjacent to the epidermis called the papillary region and a deep thicker area known as the reticular dermis. The dermis is tightly connected to the epidermis through a basement membrane. Structural components of the dermis are collagen, elastic fibers, and extrafibrillar matrix. It also contains mechanoreceptors that provide the sense of touch and thermoreceptors that provide the sense of heat. In addition, hair follicles, sweat glands, sebaceous glands (oil glands), apocrine glands, lymphatic vessels, nerves and blood vessels are present in the dermis. Those blood vessels provide nourishment and waste removal for both dermal and epidermal cells.

Anti-aging repair mask

InactiveCN107308039ARegulates the skinRepair skinCosmetic preparationsOrganic active ingredientsBetaineInjury Site
The invention discloses an anti-aging repair facial mask, which comprises components such as diterpene from basil, flavone from Budisma flavonoids, flavonoids from kapok, glycerin, butanediol, betaine, trehalose, nicotinamide and the like. Adding natural diterpenoids, flavonoids and flavonoids active ingredients in the facial mask can effectively interrupt the peroxidation chain reaction, remove free radicals, chelate metal ions, and regulate inflammatory cells to achieve Delays cell aging, repairs and prevents cell damage; in addition, the flavonoids of Budisma can activate its repair genes, promote the repair of damaged parts, and prevent inflammation from expanding or lasting too long. The secretion and transfer of semaphorin indirectly regulates the occurrence of repair and inflammation, and regulates the fluidity of the biofilm, thereby strengthening the elastic fibers of the dermis, stabilizing the cell structure, and achieving a significant repair effect; the facial mask of the present invention can also moisturize, replenish water and Whitening effect.
Owner:FOSHAN HUIFEN COSMETICS TECH CO LTD

Improved medicinal compositions comprising buprenorphine and naltrexone

InactiveCN101622014AOrganic active ingredientsNervous disorderBlood plasmaMucous membrane
An analgesic composition, in parenteral unit dosage form or in a unit dosage form suitable for delivery via the dermis or mucosa, comprises buprenorphine and an amount of naltrexone such that the ratio by weight of buprenorphine to naltrexone delivered to or reaching the plasma of a patient is in the range 100:1 to 5000:1. The analgesic action of the buprenorphine is potentiated by the low dose of naltrexone. Also provided are a method of treatment of pain and the use of buprenorphine and naltrexone for the manufacture of a medicament.
Owner:RB PHARMA

Analysis method for drugs in tissues

PendingCN114323894AAvoid Horizontal SlicingShorten experiment timeMaterial analysis using wave/particle radiationPreparing sample for investigationPharmaceutical drugStratum corneum
The invention provides a method for analyzing drugs in tissues. Quantitative analysis and detection are carried out on drug distribution conditions in in-vitro tissues by adopting a quantitative whole-body radioautography (QWBA) technology and a tissue embedding section. According to the invention, transverse slicing after longitudinal slicing is avoided, the experiment time is saved, the structure of each layer of the skin is accurately positioned, and the distribution condition of drugs in the cuticle, epidermal layer, dermis layer and subcutaneous tissue of the skin can be visually observed. And similar effects are achieved on other tissues.
Owner:XBL-CHINA INC

Medicine box for wound healing and preparation method thereof

InactiveCN110339060APromote healingAvoid churnCell dissociation methodsEpidermal cells/skin cellsWound healingMedicine
The invention discloses a medicine box for wound healing. The medicine box comprises a fibronectin external preparation and an epidermal basal cell suspension which independently exist, wherein the fibronectin external preparation is prepared from fibronectin and pharmaceutically acceptable auxiliary materials. In the wound healing process using the medicine box for wound healing, firstly, the fibronectin is sprayed on a fresh granulation wound obtained after debridement or transplanted acellular allogenic dermis, then epidermal basal cells are sprayed so that the cells can effectively adhereto the wound or the transplanted acellular allogenic dermis to prevent the cell loss, and therefore wound healing can be effectively promoted and the wound healing quality is improved. The medicine box for wound healing can be used for plastic repair of wounds formed by burns, scalds, diabetic ulcers, scar removal, pigmented nevus removal, subcutaneous lump removal and the like, is remarkable in effect, can accelerate wound healing and can remarkably improve the healing quality.
Owner:GUANGZHOU MAISHIDI MEDICAL TECH CO LTD

Method for separating pig skin epidermis and dermis

InactiveCN106895990AImplementing Hierarchical Distribution ResearchAccurate methodWithdrawing sample devicesDermisMicroscope
The invention belongs to the technical field of dermatologic medicine pharmacokinetics and discloses a method for separating pig skin epidermis and dermis. The method includes: using a microscope to precisely measure the thickness of the epidermis and the dermis, and using the frozen section technology to separate the epidermis and the dermis so as to achieve medicine skin hierarchical distribution researches. The method is scientific, effective, precise, free of pollution, quite significant to the preclinical pharmacokinetics researches of local external-use medicine, few in influence factors and simple to operate.
Owner:湖北省疾病预防控制中心
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