30 results about "Dosage form" patented technology

A particulate co-processed composition comprising microcrystalline cellulose and at least one sugar alcohol is disclosed. A preferred sugar alcohol is mannitol. The composition has an improved compactability profile, lubricant sensitivity, and ejection profile compared to microcrystalline cellulose and the at least one sugar alcohol, either alone or in combination as a simple dry blend, in the preparation of solid dosage formulations, such as tablets. Tablets comprising the particulate co-processed composition, an active, and, optionally, one or more other excipients, and method for their preparation, are also disclosed.

A chewing spirulina tablet is prepared from spirulina and two or more of dextrin, microcrystalline cellulose, mannitol, xylitol, aspartame, glycyrrhizin, essence powder, superfine silica gel powder, and magnesium stearate through mixing, granulating by use of alcohol solution containing polyvitone K30, drying and die pressing.

The invention provides novel curcuminoid formulations which have improved aqueous solubility and bioavailability when compared to known curcuminoid dosage forms. Formulations of the invention exhibit an enhanced intestinal absorption of curcuminoids, a slower curcuminoid metabolism and a reduced rate of systemic curcuminoid elimination. Additionally, upon administration in vivo, the formulations described and claimed herein produce a high, sustained level of the curcuminoid metabolite tetrahydrocurcumin. For example, at about eight to about ten hours after oral administration to a human, tetrahydrocurcumin plasma levels of between about 50 ng/mL to about 175 ng/mL are detectable, even when that metabolite is absent from the administered formulation. Novel processes for making curcuminoid formulations which have improved aqueous solubility and oral bioavailability, and methods of treating a wide variety of inflammatory, immune and neurogenerative disorders and cancers, are also provided.

The invention relates to a traditional Chinese medicine compound pharmaceutical composition and a preparation method and application thereof. The traditional Chinese medicine compound pharmaceutical composition contains clove, Salvia miltiorrhiza, dodder, epimedium, fructus cnidii, radix codonopsitis, radix astragali, angelica, rhizoma ligustici wallichii, phellodendron, radix scutellariae, rhizoma coptidis, Gardenia, ebony, hawthorn and kaki calyx. The traditional Chinese medicine compound pharmaceutical composition has the efficacies of replenishing Qi to invigorate the spleen, warming uterus and tonifying Yang, tonifying kidney and consolidating, nourishing blood and tonifying Qi, activating blood flow and removing blood stasis and clearing heat and detoxicating and has the functions of preventing and curing the inflammations of the fallopian tubes of the laying fowls. The traditional Chinese medicine compound pharmaceutical composition has definite curative effect, rapid action, safe use and no toxic and side effects or residuals, meets the demand of safety of animal-derived foods, is easy to realize industrial production and does not have pollution on the environment. The invention also provides a preparation method of the traditional Chinese medicine compound pharmaceutical composition and the application of preventing and curing the inflammations of the fallopian tubes of the laying fowls and improving the laying function. The traditional Chinese medicine compound pharmaceutical composition can be a powder. The invention also provides a feed containing the traditional Chinese medicine compound pharmaceutical composition.

The invention discloses a microbicide composition and an application thereof. The microbicide composition comprises an active ingredient and a chelating agent, wherein the active ingredient comprises Zhongshengmycin and chitooligosaccharides, and the weight ratio of the Zhongshengmycin to the chitooligosaccharides to the chelating agent is 1: (0.1 to 15): (5 to 30). The chelating agent comprises at least one of edetic acid, sodium metaphosphate, sodium tripolyphosphate, ammonium citrate, potassium sodium tartrate and aminotriacetic acid. When wettable powder, water-dispersible granules and soluble liquid agents prepared from the microbicide composition disclosed by the invention and microbicides of other compositions and dosage forms are used in a tumble-blend manner, flocculation, precipitation and the like are not caused, and the pesticide effect of tumble-blend use is remarkably improved.

The invention discloses a lung cancer and breast cancer treatment compound preparation containing active ingredients of traditional Chinese medicine and a preparation method of the lung cancer and breast cancer compound preparation. The lung cancer and breast cancer treatment compound preparation is made from erianin, taxol, bufalin and bruceine D according to a certain weight ratio. According to the preparation method, liposomes are prepared according to an ethyl alcohol injection method or dropping pills are prepared by taking polyethylene glycol as a base material to obtain the lung cancer and breast cancer treatment compound preparation containing the active ingredients of the traditional Chinese medicine. The form of the compound preparation is compound liposomes and compound dripping pills. According to animal in-vivo anticancer pharmacological experiments, the lung cancer and breast cancer treatment compound preparation containing the active ingredients of the traditional Chinese medicine has obvious inhibiting effect on growth of lung cancer and breast cancer and has higher anticancer activity than chemotherapeutic drug 5-fluorouracil.

The present invention is a combination formulation of nutrient ingredients that have been selected and combined in quantities and concentrations that offer human nutritional support as shown in various literature. The present invention, also known as CATALYST GOLD, combines herbal, mineral, vitamin, and superfood supplements to help create a catalyst effect within the body to assist lasting permanent lifestyle and bodily changes. The selected nutrient ingredients provide nutritional support for a broad variety of conditions for example, individuals who are depleted due to chemotherapy, drug addiction, and general poor diet. The present invention also provides an easily orally dosed combination of nutrient ingredients in a small dosage form. The present invention may also be conveniently taken throughout the day to maximize support and ingredient quantities through repeat dosing.

The invention discloses a traditional Chinese medicinal composition for treating hepatitis and a preparation method thereof. The traditional Chinese medicinal composition for treating the hepatitis is prepared from the following raw materials: pseudo-ginseng root, golden thread, baical skullcap root, amur corktree bark, rhubarb, spreading hedyotis herb, snake gall, borneol, calculus bovis factitius, aritificial musk, curcuma aromatica and red yeast. The traditional Chinese medicinal composition for treating the hepatitis can be prepared into multiple common formulations for oral administration. The traditional Chinese medicinal preparation treats the hepatitis by clearing heat, detoxicating, removing blood stasis, eliminating stagnation, invigorating blood circulation, dissolving stasis, detoxicating and normalizing gallbladder, has the obvious effects of improving liver function and inhibiting liver injury and hepatitis virus, addresses both symptoms and root causes, requires a short treatment period, realizes a low relapse rate, and has the obvious pharmacological action of protecting the liver and reducing transaminase and serum bilirubin.

The invention discloses a pesticide composition containing folpet and fluopyram. The pesticide composition comprises at least two active components, i.e., folpet and fluopyram, wherein a weight ratio of folpet to fluopyram is 1: 5 to 20: 1, preferably, 1: 1 to 5: 1, and the pesticide composition has synergistic effect on crop control within the above proportional range. Any agriculturally acceptable dosage form may be prepared from the pesticide composition in the invention by using any conventional technical means available to those skilled in the art, and the dosage form includes, but is not limited to, missible oil, wettable powder, a suspension, a water-dispersible granule, an emulsion in water, a microemulsion and a granule.

The present invention relates to a water-releasing stick-type cosmetic and, specifically, to a water-releasing stick-type cosmetic containing: an oily portion; and a water-releasing ingredient that is spread out in the oily portion, wherein the water-releasing ingredient has water particles encompassed by a plurality of plate-shaped materials to which emulsifiers are bound. According to the present invention, provided is a water-releasing stick-type cosmetic, which can provide a moist and cool feeling by directly supplying a large quantity of water, has excellent dosage form stability by having a hardness suitable for stick cosmetics, and simultaneously has excellent application texture, excellent storage stability and excellent color tone.

The invention belongs to the technical field of medicines, and discloses an apocynum venetum leaf valid target and an application thereof. The apocynum venetum leaf valid target provided by the invention is a flavonoid substance with purity of more than 50%. The apocynum venetum leaf valid target provided by the invention is capable of substantially reducing blood pressure of SHR hypertension rats. The valid target can be prepared into any clinically or pharmaceutically acceptable dosage form, and preferably an oral preparation.

The medicine for treating heart diseases is prepared with fleeceflower root, epimedium, flavescent sophora root, schisandra, red sage and other Chinese medicinal materials and through drying, crushing, 120 mesh sieving, mixing, disinfection and other steps. It may be prepared into various forms, including medicine powder, water pills, honeyed bolus, capsule, etc. It has high curative effect on coronary heart disease, fibrillation, insufficient blood supply, etc. and is suitable for patients of cardiac vascular diseases in different age.

The invention discloses a drug for treating arrhythmia. A nardostachys chinensis batal medicinal material is extracted firstly by using ethanol to obtain a nardostachys chinensis batal ethanol extract, and then, the nardostachys chinensis batal ethanol extract is prepared into the required dosage form. The ethanol extraction method comprises the following steps of: (1) crushing the nardostachys chinensis batal medicinal material, then, adding over 95% of ethanol with the concentration of 8-12 times, soaking at room temperature for 12-24h, filtering and collecting filtrate; (2) coldly soaking and extracting the filtrate twice according to the method in step (1), and respectively collecting filtrates; and (3) mixing all the filtrates, and then carrying out vacuum concentration. The drug has a remarkable curative effect for the pathogenesis of arrhythmia and particularly for atrial arrhythmia, atrial premature beat, atrial tachycardia, atria flutter, atrial fibrillation and the like and is little in toxic or side effect and good in patient compliance.

Gastric retentive dosage forms for controlled release of polypeptides are described. Methods of treatment using the dosage forms and methods of making the dosage forms are also described.

The invention relates to a bactericidal composition containing pydiflumetofen and oxine-copper. The compound preparation is mainly prepared from pydiflumetofen and oxine-copper, and can be prepared into water dispersible granules and suspending agent spray. Indoor bacteriostasis and field test determination show that the compound preparation has a very good prevention and treatment effect on applealternaria leaf spot disease bacteria. The dosage form is environment-friendly in processing, high in selectivity and simple to use, and has extremely high operability and practical application value.

A low viscosity eye make-up cosmetic composition that includes wax is provided. The eye make-up cosmetic composition includes both crystalline wax and non-crystalline wax. As a result, even if this eye make-up cosmetic composition includes wax, it can still display a characteristic of low viscosity so as to be applicable to a soft pencil-typed eye make-up product and to an eye make-up product thatis used by spraying composition through a spray head. The eye make-up cosmetic composition has an oil-phase matrix formulation, and thus shows significantly improved endurance and water resistance.

The invention discloses a romidepsin acetate crystal form and a preparation method thereof. by the romidepsin acetate crystal form, solubility and stability of romidepsin are improved, application ofromidepsin in tumor treatment and HIV treatment can be expanded, and a research basis can be provided for developing more romidepsin acetate dosage forms.

The invention relates to a Chinese medicinal composition and preparing process thereof, wherein the composition can be used for treating vertigo, hypochondriac pain, cephalalgia, and limb pain. The preferred dosage forms include drop pill and soft capsule.

The invention belongs to the field of plant protection, and relates to a combined medicine for protecting plants from being damaged by rhynchophorus ferrugineus, wherein the combined medicine is prepared by mixing chlorantraniliprole, kasugamycin, hydroxyenadenine and amino acid, and can be made into dosage forms such as granules, water aqua, smearing agent, powder, emulsion and the like by addingconventional pesticide auxiliary materials. The chlorantraniliprole, the kasugamycin, the hydroxyenadenine and the amino acid are matched and applied to wounds of palm plants, rhynchophorus ferrugineus larvae can be effectively prevented from boring stems from the wounds to eat soft tissues, trunks are protected against the influence of plant germs, the purpose of complementation of different effects is achieved, the pesticide application cost is reduced, and the prevention and treatment effect is improved.

The present invention provides ingestible dosage form articles such as opaque capsules with reduced light transmittance.