45 results about "Microsphere" patented technology

The invention discloses magnetically fluorescent bifunctional microsphere and a preparation method thereof. The nanometer microspheres with the magnetically fluorescent function are obtained mainly by wrapping the surfaces of magnetic nanoparticles with polyaniline macromolecules and successfully connecting fluorescent nanometer material quantum dots through functional amino groups at the terminals of the polyaniline macromolecules. The magnetically fluorescent nanometer microspheres have the excellent fluorescence characteristics of the quantum dots and the superparamagnetism of the magnetic particles and can be collected and separated through a simple applied magnetic field. The magnetically fluorescent bifunctional microspheres can be applied to the fields of immunodetection, targeted therapy, cellular seperation and the like.

The invention provides a micro-fluidic chip for preparing microspheres and a using method of the micro-fluidic chip. The micro-fluidic chip is mainly compounded by a chip body, a cooling chip and a volatilizing and exhausting chip. The micro-fluidic chip is characterized by comprising two V-shaped mixing pipelines I and II which are integrally U-shaped, circular cooling double U-shaped pipelines, a sizing and collecting pond which is arranged on one side of the circular cooling double U-shaped pipelines, an outlet and the like. The invention further provides a using and operating method of the chip. The micro-fluidic chip provided by the invention has the beneficial effects that the prepared microspheres are small in particle size dispersity and high in dimensional precision, compound microspheres with more than two components can be quickly prepared, the production efficiency is high and the operation is convenient and simple.

Syntactic foams and thermal insulation as described containing epoxy resin, hollow microspheres, and dried sol-gel or fumed metal oxide for forming a thermal insulating layer on a substrate such as a pipeline. Methods for forming such thermal insulating layers are also described, which can include formulating with blowing agents for forming closed cells in the finished insulating foam.

The invention discloses a coating having heat-insulation and reflection functions. The coating comprises, by weight, 40-60 parts of a pure acrylic emulsion, 30-40 parts of hollow glass microspheres, 20-30 parts of ceramic microspheres, 10-30 parts of expanded perlite, 10-20 parts of titanium dioxide, 5-15 parts of mica powder, 3-8 parts of kaolin, 5-10 parts of barium sulfate, 2-8 parts of carboxyethyl cellulose, 5-10 parts of nano-silica, 8-15 parts of nanometer metal oxide, 3-8 parts of a filler, 1-5 parts of a film forming assistant, 4-8 parts of an assistant and 30-50 parts of deionized water. The coating having heat-insulation and reflection functions has good economic property, and also has heat-insulation and light and heat reflection functions.

A making method of a composite type biological chip based on a photonic crystal comprises four steps which are preparation of hard substrates, preparation of photonic crystal thin membranes, connection of membranous substrates and surface treatment of the substrates. (1) the preparation of hard substrates: common hard substrates are cleaned by soapy water, washed by de-ionized water and dried, and amino-group or hydroxyl is decorated on the surfaces of the substrates; (2) the preparation of photonic crystal: the nano-microspheres such as specific monodisperse silicon dioxide or polystyrene and the like, which are different in size according to the positions of testing signals, are assembled on the surfaces of the treated substrates to form the photonic crystal thin membrane with the thickness of 20 to 30 microns (3) the connection of membranous substrates: the surface of the photonic crystal thin membrane is laid with a layer of the membranous substrate and the connection is fixed by utilizing the chemisorption or the mutual function between positive and negative charges; (4) the surface treatment of the substrates: by using the methods such chemisorption and the like, chemical groups which can be fixedly connected with biomolecules to be tested are decorated on the membranous layer parts of the surfaces of the composite substrates which are formed in the step (3).

The invention discloses a building method of a molecularly imprinted fluorescent probe, wherein the material is Mn:ZnS quantum dot-molecularly imprinted polymer composite microsphere, which is formed by Mn:ZnS quantum dot, a styrene-polyacrylic acid copolymer and template molecule thiabendazole in a copolymerization manner under the ultrasonic action, so as to form a sensing probe with specific recognition after the template molecule thiabendazole is removed. The building method has the advantages that the molecularly imprinted fluorescent probe is designed and built by the Mn:ZnS quantum dot as a fluorescent sensor unit by using a molecular imprinting technique on the basis of the fluorescence resonance energy transfer mechanism; the Mn:ZnS quantum dot and the benzimidazole are subjected to fluorescence resonance energy transfer when the template molecule thiabendazole enters a hole of the Mn:ZnS quantum dot-molecularly imprinted polymer composite microsphere, thus resulting in quenching of emitted orange fluorescent light. Therefore, benzimidazole in the water can be specifically identified by an output change of a fluorescent signal.

The invention discloses a wear-resistant heavy oil catalytic cracking catalyst capable of reducing sulfur content of gasoline. Based on the total mass of the catalyst, the wear-resistant heavy oil catalytic cracking catalyst comprises not less than 15 mass percent of mullite, 0.05-20 mass percent of vanadium in terms of vanadium element and 15-50 mass percent of Y-type molecular sieve. The wear-resistant heavy oil catalytic cracking catalyst is prepared by taking mullite microspheres, which are synthesized at low temperature by taking a large amount of vanadium-containing compound as a phase change auxiliary agent, as a raw material, performing in-situ crystallization on the microspheres to synthesize a NaY molecular sieve, modifying and exchanging. The wear-resistant heavy oil catalytic cracking catalyst has rich middle pores and macropores, is strong in wear resistance, can reduce the sulfur content of the gasoline in a catalytic cracking process and has an excellent heavy oil cracking function.

The invention discloses high infrared shielding rate thermal insulation paint. The paint is prepared from substrate paint, SiO2 aerogel, hollow glass beads with an indium and antimony co-doped type tin oxide coating, surfactant, a curing agent and auxiliaries; in the tin oxide coating, the doping ratio of indium ranges from 0.5 mol% to 3 mol%, and the doping ratio of antimony ranges from 6 mol% to10 mol%; the particle size of the hollow microspheres ranges from 1,000 meshes to 2,000 meshes; the surfactant is anion and amphoteric mixed surfactant; the auxiliaries comprise a dispersing agent, awetting agent, a defoaming agent and a flatting agent. The paint has an infrared light shielding barrier forming a large specific surface area, and can effectively insulate heat and absorb and shieldthe infrared light within a wide wavelength range. The paint prepared through a method has the good homogeneity, the SiO2 aerogel can be uniformly dispersed in the paint system, and then the obtainedcoating has the uniform and stable heat insulation and infrared light shielding performance.

The invention provides a three-dimensional wrinkle polylactic acid microballoon and a preparation method and uses thereof. The preparation method of the three-dimensional wrinkle polylactic acid microballoons is as follows: adopting ammonium bicarbonate deionized water solution of Fe3O4@ SiO2 nanoparticles as an inner phase, dichloromethane solution of polylactic acid as an interphase, deionized water solution of polyvinyl alcohol as an outer phase, and obtaining the three-dimensional wrinkle polylactic acid microballoons. The gas produced by the ammonium bicarbonate introduces mismatched stresses at emulsion interface, the nanoparticles added in the emulsion introduce multiple-gasification cores, and the three-dimensional wrinkle polylactic acid microballoons are successfully prepared and used in oil water separation and cell adsorption. The three-dimensional wrinkle polylactic acid microballoons are in multi-stage porous structure which can effectively increase specific surface area and can be used effectively in oil-water separation, and has good bio-compatibility which can be used in effective cell adhesion. The three-dimensional wrinkle polylactic acid microballoons have an excellent prospect in bio-application.

The invention provides preparation and application of nano zeolite reinforced xanthan gum composite hydrogel functional microspheres. The method selects a nanoscale zeolite molecular sieve which is synthesized by a template-free and low-cost manner, then premixes the nanoscale zeolite molecular sieve into a xanthan gum-sodium alga acid binary natural polysaccharide aqueous solution to prepare nano zeolite molecular sieve reinforced organic-inorganic composite hydrogel functional microspheres. Corresponding nano zeolite has a clear synergetic heavy metal adsorbing behavior; meanwhile, a corresponding xanthan gum-sodium alga acid binary polysaccharide cross-linking matrix has a richer micro three-dimensional network structure, thus micro channels of the nano zeolite, which are evenly distributed, directionally interact with polysaccharide molecular characteristic functional groups. The prepared microspheres have satisfactory effects of absorbing and removing cobalt ions and nickel ions in simulation nuclear industry wastewater.

The invention provides a preparation method for polyvinyl alcohol/silicon dioxide composite microspheres and belongs to a preparation method for a composite microsphere material. Polyvinyl alcohol and tetraethyl orthosilicate are employed as raw materials, and polyvinyl alcohol/silicon dioxide (PVA/SiO2) composite microspheres are prepared in a water-in-oil system without any surfactants. Tetraethyl orthosilicate is hydrolyzed fully in a PVA solution in an acidic condition, and uniform PVA/SiO2 composite sol is formed; the sol is subjected to dispersion and crosslinking in a water-in-oil system without surfactants, and finally PVA/SiO2 composite microspheres are obtained. The technology is simple, the repeatability is good, energy consumption is low and the cost is low. Surfactant residual and agglomeration of nano inorganic particles in the process of preparing composite microspheres through a traditional emulsification method are avoided. The microspheres are advantaged by regular sphere, high dispersibility and uniform microstructure, and can be used as a drug carrier, an injection-type bone tissue repairing material or a heavy metal ion adsorption material.

A series of amphiphilic polymer materials which take pulullan as a main chain and polyester as a branch chain are synthesized. By adopting a novel synthetic method, the synthetic time of the series of amphiphilic polymer materials is shortened to 5 minutes, so that the materials have a relatively high industrial value. The series of amphiphilic polymer materials have multi-aspect application values in the field of medicine transfer such as microsphere and nanoparticle reparations and the like as well as modification of other medicine transfer systems and the like. The series of amphiphilic polymer materials are used for preparing nanoparticles and microsphere conveying transfer medicine or modification medicine transfer carriers such as nanoparticles and microspheres so as to achieve the purpose of increasing the solubility and stability of medicines, improving the curative effect of the medicines and reducing the toxic and side effects of the medicines. The series of materials, which are used as the medicine transfer carriers or modification medicine transfer carriers, can be used for achieving the purpose of liver targeting delivery and temperature sensitive control released delivery at the same time.

The invention discloses a biological active ceramic bracket with a nano/micron hierarchical pore structure and a preparation method of the biological active ceramic bracket. The preparation method includes the following steps that (1) monodisperse microspheres with the particle size height capable of being controlled are prepared through a soap-free emulsion method; (2) the microspheres are evenlydispersed in ceramic paste, and the ceramic paste with good printability is obtained; (3) the biological active ceramic bracket with the micron order pore size is printed through a 3D printing technology; (4) the printed bracket is sintered, and the biological active ceramic bracket with the nano/micron hierarchical pore structure is obtained. According to the biological active ceramic bracket with the nano/micron hierarchical pore structure and the preparation method of the biological active ceramic bracket, pore-formingtemplates with the particle size capable of being controlled are evenlydispersed in the printing paste, the sintering characteristics of ceramic and the characteristics of precise control of the micropore structure through the 3D printing technology, the biological active ceramic bracket with the nano/micron hierarchical pore structure is successfully and precisely constructed, and the difficult problem that existing 3D printing technologies cannot accurately controlthe nanoscale pore structure is solved.

The invention relates to a composite microsphere with a radial fibrous mesoporous shell layer/hollow nuclear layer structure and a preparation method of the composite microsphere. The composite microsphere is provided with a cavity, a nuclear layer and a mesoporous shell layer, wherein the mesoporous shell layer is provided with radial fibrous mesoporous channels. The composite microsphere is highin sphericity and surface regularity, uniform in particle size distribution and high in monodispersity and strength. The preparation method of the composite microsphere is simple and feasible and facilitates industrialization; preparation of the radial fibrous mesoporous shell layer and removal of an organic template can be completed by means of a one-step method. The composite microsphere has the advantages of high light scattering efficiency, large specific surface area, low density, high porosity and the like, can be widely applied in light diffusion materials and used as a light diffusionagent for heavy haze and can also be adopted in the fields of fillers of coatings, cosmetics, catalysts and water treatment.

The invention provides a full-frequency wave-absorbing high-temperature heat-insulating stealth integrated paint. The paint comprises: high temperature-resistant reinforced chopped fiber, pressure-resistant hollow microspheres, a wave-absorbing agent, resin and a solvent. According to the full-frequency wave-absorbing high-temperature heat-insulating stealth integrated paint, carbon nanotubes anda magnetic absorbent are effectively compounded and combined, so that the reflection and absorption performance of a coating can be improved. The paint coating has high-temperature resistance, heat insulation and full-frequency wave absorption, can be used on the outer surfaces of weaponry and aircrafts, achieves effective thermal protection on the weaponry and the aircrafts, and also has a full-frequency band stealth effect at the same time. The paint can be applied to various types of airplanes, missiles and the like which have requirements for high-temperature resistance, heat insulation and invisibility, and has important significance for improving the autonomous ability of national defense and military industry production in China and enhancing the comprehensive strength of China.

The invention relates to an immobilized enzyme based protein enzymolysis method. The method adopts temperature sensitive microspheres as the immobilized enzyme carrier, performs temperature regulationof the hydrophilic and hydrophobic properties of the temperature sensitive immobilized enzyme microspheres so as to control the protein enzymolysis process, i.e. when the enzymolysis temperature is higher than a critical phase inversion temperature of the temperature sensitive immobilized enzyme microspheres, the microspheres are hydrophobic, while a to-be-tested protein sample is enriched, enzymolysis is carried out on the microspheres, when the enzymolysis temperature is lower than the critical phase inversion temperature of the temperature sensitive immobilized enzyme microspheres, enzymolysis is stopped and peptide fragment is released, thereby improving the enzymolysis efficiency and detection rate of the sample peptide fragment. The protein enzymolysis method provided by the invention has the characteristics of simple steps, convenient operation and the like, and is conducive to research of proteomics and related fields.

The invention discloses a preparation method of a polyurethane heat preservation plate, and belongs to the technical field of preparation of heat preservation plates. The preparation method comprises the following steps: smashing and screening expanded perlite, stirring and mixing the expanded perlite powder with calcined lime to prepare initiator powder, adding mixed powder prepared from portland cement and the like into the initiator powder, then adding packing microspheres prepared by mixing white emulsion and the like, adding polypropylene fibers to improve the anti-cracking performance of the plate, performing stirring reaction with self-made foam polyurethane, stewing and foaming in a die, and performing constant-temperature and constant-humidity steam curing to prepare the polyurethane heat preservation plate. The preparation method has the beneficial effects that the preparation steps are simple, and the obtained polyurethane heat preservation plate is relatively high in size stability, and has the compression strength greater than or equal to 306 kPa; the polyurethane heat preservation plate is easy to construct; after the polyurethane heat preservation plate is constructed, no cracks are formed on the surface layer; the polyurethane heat preservation plate is high in heat preservation performance and long in service life.

The invention discloses a preparation method of modified biochar immobilized petroleum degrading bacterium microspheres, which comprises the following steps: taking reed biomass powder, carbonizing, and activating in CO2 atmosphere to obtain a modified biochar carrier; placing the modified biochar carrier and a petroleum degrading bacterium solution in an immobilized culture medium for mixed adsorption to obtain the modified biochar adsorbing the microbial inoculum; a chitosan solution is used as an embedding agent to embed the modified biochar adsorbing the microbial inoculum, and the modified biochar immobilized petroleum degrading bacterium microspheres are obtained. The reed biochar is modified in a CO2 activation mode, the specific surface area and the pore volume of the immobilized carrier are effectively increased, chitosan is adopted as an embedding material, the degradation efficiency of petroleum degrading bacteria on petroleum is effectively improved, waste reeds are recycled, the problem of constructed wetland waste disposal can be solved, and the method is suitable for industrial production. The resource utilization of wastes is realized.

The invention relates to synthesis of fluorescent hollow spheres, in particular to a preparation method of CaCO3:Eu<3+> fluorescent hollow microspheres. The preparation method of the CaCO3:Eu<3+> fluorescent hollow microspheres comprises steps as follows: a) a carbonate raw material, a calcium-containing raw material, a europium-containing raw material and a soft template agent are weighed according to the stoichiometric ratio, added to deionized water respectively and sufficiently stirred, and uniform solutions are formed; according to the stoichiometric ratio, Eu<3+> doped CaCO3 is taken as a target product with the general formula being Cal(1-x)EuxCO3, and the doping amount x of Eu<3+> ranges from 0.01 to 0.10; b) a carbonate solution is dropwise added to calcium and europium solutions mixed with the soft template agent during magnetic stirring, the mixed solution is aged and then subjected to suction filtration and washing, and precipitates are dried in a freeze drying box for 12-24 hours. The CaCO3:Eu<3+> fluorescent hollow microspheres are prepared with the soft template method, the template agent is not required to be removed additionally in the preparation process, and the preparation process is reduced. Besides, the prepared CaCO3:Eu<3+> fluorescent hollow microspheres are lower in price as compared with common oxide fluorescent hollow microspheres and also have double functions of drug/catalyst loading and fluorescent tracing. Therefore, the product performance is high, the procedure is simplified, the cost is low, and the application field is wide.

The invention relates to a kit of a peripheral blood free-nucleotide miRNAs-based ultrasensitive detection device and a detection method of the kit. The kit comprises 1) a microarray detection pool; 2) an external magnetic field; 3) premixed reaction solutions A and 4) premixed reaction solutions B. During detection of multiple targets to be detected, the premixed reaction solutions A for respectively and correspondingly detecting the targets to be detected are configured in parallel and are respectively marked as a premixed reaction solution A1 and a premixed reaction solution A2. The kit iscombined with biomolecular diagnosis, nano-magnetic microsphere enrichment and biochip technologies to develop a novel technique capable of directly and accurately detecting peripheral blood miRNAs related to occurrence, development and drug resistance of a malignant tumor without amplification at high sensitivity and high flux. The kit has an important value in the aspects of noninvasive detection of medical tumors, personalized medicine application, survival after chemotherapy and the like.

The invention discloses a medium microsphere assisted detection thin film and a preparation method thereof, and a super-resolution detection method. The medium microsphere assisted detection thin filmcomprises a plurality of tightly connected chambers, each chamber is filled with a medium microsphere, the chambers and medium microspheres are encapsulated in a shell body, the uniform periodic arrangement of the microspheres is easy to realize, and the problem of the uniform periodic arrangement of the medium microspheres is solved; localized super-resolution detection of an object is realizedby changing positions of the medium microspheres; spatial morphologies of the medium microspheres are changed by extending a PDMS thin film, and the micro-manipulation of object monitoring performanceis realized; and the problem that the medium microspheres must depend on the liquid infiltration method to change the super-resolution in the microspheres and at the microsphere boundary is solved.

The invention discloses special graphene heat-resisting master batch for a hot water plastic pipe and a preparation method. The preparation method comprises the following steps: a, dissolving tetraethyl orthosilicate into de-ionized water and adjusting the pH (Potential of Hydrogen) value to prepare a tetraethyl orthosilicate solution; b, immersing a graphene-loaded porous calcium phosphate microsphere into the tetraethyl orthosilicate solution; raising the temperature, stirring and reacting; then washing and drying; grinding into powder to obtain silica gel coated porous calcium phosphate composite powder; and c, after impregnating the composite powder with an organic solvent, mixing with a polymer and a dispersant and extruding and granulating to prepare the graphene heat-resisting master batch. The method disclosed by the invention has the following beneficial effects that the problem that graphene is easy to agglomerate is effectively solved through the preparation method, uniformdispersion of the graphene in a plastic matrix can be ensured and the uniformity of a plastic product is improved; the obtained plastic product has excellent heat-resisting performance and mechanicalproperties; and a preparation process is simple and low in cost and can be popularized and applied.

The invention relates to porous MoO2 photocatalyst microspheres with a hierarchical structure and a preparation method thereof, and belongs to the photocatalyst microspheres and the preparation methodthereof. The porous MoO2 photocatalyst microspheres are composed of a porous outer shell and an inner reticulated porous skeleton. The method comprises the steps: with citric acid as a fuel, ammoniumparamolybdate as a raw material and water as a solvent, carrying out magnetic stirring to form a mixed solution, then, spraying the solution into a tubular furnace with the temperature of 400-500 DEGC by ultrasonic atomization, and obtaining the porous MoO2 photocatalyst microspheres with the hierarchical structure. The preparation system has the advantages of simple operation of technological method, low cost of raw materials, economic feasibility and the like. The catalyst prepared by the method has a special hierarchical structure, and has the hollow and porous morphological characteristics, small particle size, uniform distribution and no agglomeration. The diameter of the microspheres is between 0.5 and 2 [mu]m. The catalyst has good photocatalytic performance and good hydrophilicity, and is beneficial to the application in the fields of photocatalysis, water pollution treatment, lithium ion batteries, supercapacitors, gas sensors and the like.

The invention relates to a preparation method of a flexible conductor wire. The preparation method comprises following steps of S11: preparing microsphere dispersion liquid, adding microspheres into a solvent, and dispersing the microspheres uniformly to obtain the microsphere dispersion liquid; S12: preparing a microsphere template array, coating a substrate with the microsphere dispersion liquid, and drying the microsphere dispersion liquid to remove the solvent, and obtaining the microsphere template array; S13: depositing metal lines, depositing metal layers on the microsphere template, wherein the metal layers on the surfaces of the microspheres and poured into slits among the microspheres form a metallic film being of a net structure; and S14: forming the flexible conductor wire, and etching the metallic film being of the net structure to form the flexible conductor wire in the predetermined shape after the substrate and the microspheres are removed. The resistivity of the flexible conductor wire provided by the invention can keep stable during the bending process, and the service life of the flexible backboard is prolonged.

The invention discloses plastering adhesive cement for an external wall surface. The plastering adhesive cement contains the following components in parts by mass: 16-20 parts of dispersed latex powder, 200-240 parts of ordinary Portland cement, 40-50 parts of coal ash hollow microspheres, 4-6 parts of glass fibers, 15-30 parts of thermal insulation powder, 20-35 parts of fireproof powder, 40-80 parts of hard calcium carbonate, 10-20 parts of metal powder and 150-200 parts of water. By adding the coal ash hollow microspheres and the thermal insulation powder, the strength of the plastering adhesive cement is similar to plastering adhesive cement added with net cement and is even higher than the adhesive cement produced by virtue of the net cement, so that the use amount of the cement is saved, the processing cost is lowered, meanwhile, the compressive strength and the bonding strength can be effectively improved, and the plastering adhesive cement has high anti-cracking strength and flame retardance, strong fire retardancy and wide application range.