The invention discloses an intelligent sliding sleeve for multi-stage fracturing of a horizontal well and relates to, but not limited to, the technical field of fracturing sliding sleeves. The intelligent sliding sleeve comprises a detection unit, a control unit and an execution unit, wherein the detection unit is provided with an antenna module, the antenna module is used for detecting a load-carrying label for recognizing fracturing fluid and transmitting an obtained signal to the control unit; the control unit is provided with an electric control module, and the electric control module is used for generating a corresponding control signal according to the received signal and transmitting the control signal to the execution unit; the execution unit is provided with a motor module, a transmission module and a sliding sleeve module, and the motor module, the transmission module and the sliding sleeve module are connected in sequence; the transmission module is used for converting the rotational movement of the motor module into linear movement and driving the sliding sleeve module to act simultaneously; and the sliding sleeve module is used for achieving opening and closing of the sliding sleeve through linear movement. By the adoption of the intelligent sliding sleeve for multi-stage fracturing of the horizontal well, full-bore production of a pipe column can be achieved, free adjustment of the opening degree and closing degree of the sliding sleeve can be achieved, and the labor intensity of workers is effectively relieved.