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1 results about "Nitromethane" patented technology

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Nitromethane is an organic compound with the chemical formula CH₃NO₂. It is the simplest organic nitro compound. It is a polar liquid commonly used as a solvent in a variety of industrial applications such as in extractions, as a reaction medium, and as a cleaning solvent. As an intermediate in organic synthesis, it is used widely in the manufacture of pharmaceuticals, pesticides, explosives, fibers, and coatings. Nitromethane is used as a fuel additive in various motorsports and hobbies, e.g. Top Fuel drag racing and miniature internal combustion engines in radio control, control line and free flight model aircraft.

Preparation method of iguratimod intermediate IV

InactiveCN107162942AReduce harmReduce pollutionSulfonic acid amide preparationChemical industryNitrobenzene

The invention discloses a method for preparing an iguratimod intermediate IV, which belongs to the technical field of medicine and chemical industry. The present invention replaces nitrobenzene with nitromethane as the preparation of Alamod intermediate IV (α-amino-2-methoxy-4-methanesulfonamido-5-phenoxyacetophenone hydrochloride ) solvent, the weight yield of the prepared Alamod intermediate IV can reach 102~105%, and the purity can reach more than 99%; in addition, the present invention adopts nitromethane as the solvent of reaction and also has the following advantages: weak smell , less pollution, less harm to the human body, easy post-processing of the product, improved purity, and no genotoxic impurity nitrobenzene residue in the final product.

Preparation method of iguratimod intermediate IV

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Owner:常州佳德医药科技有限公司

1 results about "Nitromethane" patented technology

Preparation method of iguratimod intermediate IV

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