2 results about "Photodynamic therapy" patented technology

The present invention provides an immunomodulator for use in the treatment and/or control of a neoplastic disease in a patient intended to undergo immunogenic cell death therapy simultaneously, separately or sequentially with administration of the immunomodulator. The therapy can be selected from microwave irradiation, targeted radiotherapy, embolization, cryotherapy, ultrasound, high intensity focused ultrasound, cyberknife, hyperthermia, radiofrequency ablation, cryoablation, electrotome heating, hot water injection, alcohol injection, embolization, radiation exposure, photodynamic therapy, laser beam irradiation, and combinations thereof.

The invention discloses a targeting probe for photodynamic therapy and a preparation method. The targeting probe includes a synthetic drug-loaded microbubble, a targeting molecule small peptide LHRH (gonadotropin-releasing hormone) connected to it, and a photosensitizer ZnPc (zinc phthalocyanine) wrapped in it. Compared with the traditional photosensitizers, the present invention overcomes the disadvantages of the existing photosensitizers, which are non-targeting, difficult to be enriched to reach an effective concentration, easy to agglomerate, difficult to deliver to the tumor site, and mostly limited to the tumor site in the epidermis or superficial tissue area, providing A targeted multimode probe with ultrasonic signal, photoacoustic signal and fluorescent signal for photodynamic therapy with high targeting, strong tissue penetration, good stability and strong specificity.