Magnetic nano particle magnetic-induction thermal focusing system based on complex magnetic field

A magnetic nanoparticle and composite magnetic field technology, which is applied in the field of biological and medical nanomaterials, can solve the problem of high cost, achieve low cost, reduce damage, and control the speed

Inactive Publication Date: 2011-09-14
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This technology allows for controlled cooling or warming up areas that may have cancer cells by creating tiny particles called magnetite (iron oxide) nano-particle). These small objects help reduce damage caused during treatment on healthy organs like heart muscle. They act differently depending upon how they're located within an organism. By adjusting their temperature, it helps prevent overheating while treating other parts of the body without causing harmful side reactions. Overall this technology provides technical benefits such as improved accuracy, reduced risk from excessively high temperatures compared to traditional methods used today, lower costs, ability to target specific locations inside affected regions, and more effective ways to warm certain areas than current techniques.

Problems solved by technology

Technological Problem addressed in this patents describes various technical problem areas associated with current methods of controlling nanoparticles at room temperatures without causing damage from their own intrinsic characteristics like shape changes, crystal structure variations, coercivity, and other factors affecting electrical resistance. These challenges limit how much heat may pass outwardly across the boundary layer formed around small iron cores within each individual element of the nanometer materials.

Method used

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  • Magnetic nano particle magnetic-induction thermal focusing system based on complex magnetic field
  • Magnetic nano particle magnetic-induction thermal focusing system based on complex magnetic field
  • Magnetic nano particle magnetic-induction thermal focusing system based on complex magnetic field

Examples

Experimental program
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Effect test

Embodiment 1

[0044] Embodiment 1: Magnetic induction thermal focusing under an alternating magnetic field generated by a solenoid coil.

[0045] The magnetic nanoparticles 4 select iron ferric oxide nanoparticles with an average particle diameter of 12nm. In order to improve the stability and biocompatibility of the particles, the surface is modified with dimercaptosuccinic acid, and the concentration of the magnetic nanoparticles 4 is 2 mg / cm 3 The alternating magnetic field 1 is provided by the solenoid coil 5, and its rated power is 80kw, and the frequency is 100kHz; the constant magnetic field 3 is provided by two opposite first permanent magnets 2 and the second permanent magnet 16 of the same pole, and the first permanent magnet 2 and the magnetic induction of the second permanent magnet 16 are both 0.5T, and the distance between the first permanent magnet 2 and the Dier permanent magnet 16 is 11 cm. The first permanent magnet 2 and the second permanent magnet 16 are cooled by circula

Embodiment 2

[0046] Example 2: Magnetic induction thermal focusing under an alternating magnetic field generated by a ferrite coil.

[0047] For magnetic nanoparticles, ferric oxide nanoparticles with an average particle size of 12nm are selected, and their crystal form is cubic spinel. In order to improve the stability and biocompatibility of nanoparticles, the surface is modified with dimercaptosuccinic acid. The concentration of magnetic nanoparticles is 2mg / cm 3 ; The alternating magnetic field is provided by a ferrite coil, such as image 3 As shown, it is composed of a ferrite 12 and a coil 13 wound on the ferrite 12, the rated power of the alternating magnetic field is 100kw, and the frequency is 120kHz; the constant magnetic field is provided by two permanent magnets 14 and 15 facing each other with the same pole , the magnetic induction of the seventh permanent magnet 14 and the eighth permanent magnet 15 is 0.5T, and the distance between the seventh permanent magnet 14 and the ei

Embodiment 3

[0048] Embodiment 3: Magnetic focusing under the action of a composite magnetic field in which the ferrite coil generates an alternating magnetic field and the permanent magnet array generates a constant magnetic field.

[0049] For magnetic nanoparticles, manganese zinc ferrite nanoparticles with an average particle size of 10nm are selected, and their crystal form is cubic spinel. In order to improve the stability and biocompatibility of nanoparticles, the surface is modified with dimercaptosuccinic acid , the concentration of magnetic nanoparticles is 2 mg / cm 3 The alternating magnetic field is provided by the first ferrite coil 10 and the second ferrite coil 11, its rated power is 100kw, and the frequency is 150KHz; the constant magnetic field is composed of four opposite third to sixth permanent magnets 6, 7, 8 and 9 provide that the magnetic induction of the third to sixth permanent magnets 6, 7, 8 and 9 is all 0.5T. The third to sixth permanent magnets 6, 7, 8 and 9 are

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Abstract

The invention discloses a magnetic nano particle magnetic-induction thermal focusing system based on a complex magnetic field, comprising a device for generating an alternating magnetic field and magnetic nano particles, wherein the device for generating the alternating magnetic field generates the alternating magnetic field; the magnetic nano particles are dispersed in the alternating magnetic field; the magnetic nano particle magnetic-induction thermal focusing system also comprises at least two permanent magnets which are distributed at the two sides of the device for generating the alternating magnetic field, and the same poles are opposite; and the distances from the permanent magnets to the central line of the device generating the alternating magnetic field are approximately equal. In the magnetic nano particle magnetic-induction thermal focusing system, the accurate control of the magnetic nano particle heat effect and selective temperature increasing of local positions in areas dispersed with magnetic nano particles are realized, the cost is lower, and the selective heating on tumor areas can be realized, so that the damage of thermal therapy to the normal tissues is relieved. The magnetic nano particle magnetic-induction thermal focusing system also can be applied in selective heating to areas of chemical reaction systems, so that the purpose of controlling the chemical reaction rate is achieved.

Description

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Claims

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Application Information

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Owner SOUTHEAST UNIV
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