The invention provides an externally applied plaster and an oral medicament mainly treating bone fracture. They contain natural copper, saffron, myrrh, frankincense, panax notoginseng, dragon's blood, tortoise plastron, borneol, Taishe, ground beetles and other traditional Chinese herbal medicinal components. The externally applied plaster and the oral medicament can be used in coordination. The invention also provides a preparation method of the externally applied plaster. The plaster and the medicament provided in the invention have significant curative effects on fracture, osteomyelitis and bone tuberculosis, as well as lumbar disc herniation, cervical spondylosis, scapulohumeral periarthritis, rheumatic arthritis, traumatic injuries, breast hyperplasia and other diseases, and have the characteristics of quick effect, high cure rate, no recurrence, no toxic or side effect, convenient application and low cost, etc.