The invention belongs to the technical field of
medicine synthesis, and particularly relates to a preparation method of N-diethylaminoacetyl-2,6-
dimethylaniline quaternary ammonium salt. The method for preparing the N-diethylaminoacetyl-2,6-
dimethylaniline quaternary ammonium salt comprises the following steps of: reacting 2-bromo-N-(2,6-dimethylphenyl)
acetamide serving as a
raw material with diethylaminoethanol to obtain an N-diethylaminoacetyl-2,6-
dimethylaniline quaternary ammonium salt crude product, and further stirring and crystallizing the crude product in an
organic solvent to obtain the N-diethylaminoacetyl-2,6-dimethylaniline quaternary ammonium salt pure product. The method provided by the invention has the advantages of simple
reaction conditions and simplified preparation process, effectively enhances the yield and purity of the N-diethylaminoacetyl-2,6-dimethylaniline quaternary ammonium salt, and is suitable for industrial production.