The invention discloses a swine composite interferon used for emergent prevention for the African swine fever. A protein (swine gamma interferon-connecting peptide-swine antibacterial peptide segmentfusion protein) is provided and shown in a sequence 7 of a sequence table. A gene coding the protein also belongs to the protection range of the swine composite interferon. The invention further provides a compound which comprises the protein and lentinan; in the compound, every 1.0*10<-9> mol of protein is matched with 15 micrograms of lentinan. The invention further relates to application of theprotein or the compound in preparation of an African swine fever vaccine. The invention further provides the African swine fever vaccine. The active component of the African swine fever vaccine is the protein or the compound. The protein and the compound have a good immune protection effect and are high in stability (the protein and the compound can be preserved at the room temperature and are long in preservation period). The swine composite interferon has high application and popularization value in prevention and control over the African swine fever.