The invention discloses a hydraulic pulsation assisted nitrogen-chemical flooding ground control device and an implementation method. The device comprises a hydrocyclone, an atomizer, a hydraulic pulsation starter and a pulsation generator, wherein the hydraulic pulsation starter is composed of a clamp and an external protective cover, and the clamp is inserted to prevent a piston from moving towards a stroke limiter. The device can realize the multifunctional setting of gas-liquid fixed proportion mixed injection, quantitative alternate injection, single-phase pulsation injection and the like. During implementation, firstly, high-pressure gas is utilized to form a gas channeling channel in a stratum, then atomized gas obtained after mixing and atomizing of a viscosity reducer and nitrogen is injected into the stratum, the atomized gas quickly flows to a deep part along the gas channeling channel, then a viscosity reducer solution is extruded into the stratum in a high-pressure pulsation mode, the viscosity reducer is further put into the reservoir, and then well soaking is carried out, so that the viscosity of thick oil in the reservoir is fully reduced. Gas injection, atomized gas injection, viscosity reducer solution pulsation injection and well soaking are repeated, the overall viscosity reduction of the area is realized after multiple rounds, then pulsation water injection is carried out, and the overall propulsion of the thick oil in the stratum is realized.