The invention discloses a preparation technology for neodymium-doped quartz glass used for laser. According to the invention, a sol method and a titration spray method are combined, while a sol is prepared, hexahydrate neodymium chloride, hexahydrate aluminium chloride, nano titanium dioxide, hexahydrate yttrium chloride, silanol salt, an organic solvent and water are taken as raw materials, a doped component scope is characterized by comprising 0.5-1.2 mol% of Nd3+, 0.4-6 mol% of Al3+, 0-3 mol% of Ti4+, 0-0.8 mol% of Y3+, and the balance of Si4+, the doping time is short, the Nd3+ ion doped concentration in a quartz rod can reach as high as 0.8-3.5 wt%, and the doping uniformity can reach as high as 2*10-4 magnitude; an external diameter of the quartz rod can reach Phi 30*150 mm, a peak value emission cross section of the Nd3+ ion is greater than 1.5*10-20 cm<2>, the cost of a melting technology is low, the neodymium-doped quartz glass can substitute the current Nd3+ doped phosphate glass and YAG crystal and used for laser impact reinforcement equipment and laser fusion energy generating.