Method for preparing progesterone molecular engram polymer

[0015] Example 1

[0016] Dissolve 1mmol of template molecule progesterone and 6mmol of functional monomer tetravinylpyridine into 100mL pure acetonitrile solution containing 7ml N,N'-methylenebisacrylamide and 35mg initiator azobisisobutyronitrile to prepare The mixed solution was ultrasonically degassed for 6 minutes, and nitrogen gas was passed for 10 minutes to remove oxygen molecules. After the mixed solution was sealed, it was polymerized to form a white powdery polymer by heating and stirring. The polymerization temperature was 50°C and the reaction time was 18 hours. After the polymerization is completed, use 100mL methanol and acetic acid mixed solution with a volume ratio of 9:1 to extract the synthesized polymer by Soxhlet extraction to remove the template molecules, and then extract with pure methanol to remove the acetic acid molecules . After the extraction, the polymer is placed in a vacuum drying oven to dry to constant weight, and finally the progesterone molecularly

[0017] Example 2

[0018] Dissolve 6mmol of template molecule progesterone and 6mmol of functional methacrylic acid into 200mL of pure acetonitrile solution containing 7ml of N,N'-methylenebisacrylamide and 25mg of initiator azobisisobutyronitrile to prepare a mixed solution ; Ultrasonic degassing of the mixed liquid for 6 min, and nitrogen for 10 min to remove oxygen molecules, and then after the mixed liquid is sealed, it is polymerized by heating and stirring to form a white powdery polymer. The polymerization temperature is 65° C., and the reaction time is 15 hours. After the polymerization reaction is completed, use 100mL of methanol and acetic acid mixed solution with a volume ratio of 9:1 to extract the synthesized polymer by Soxhlet extraction to remove the template molecules, and then extract it with pure methanol. Acetic acid molecule. After the extraction, the polymer is placed in a vacuum drying oven to dry to constant weight, and finally the progesterone molecularly impr

[0019] Example 3

[0020] Dissolve 10mmol of template molecule progesterone and 6mmol of functional monomer tetravinylpyridine into 300ml of solution containing 20mmol of N,N'-methylenebisacrylamide, 35mg of initiator azobisisobutyronitrile and 300mL of pure acetonitrile, Prepare the mixed liquid; degas the mixed liquid ultrasonically for 10 minutes, and pass nitrogen for 10 minutes to remove oxygen molecules, and then seal the mixed liquid and polymerize to form a white powdery polymer by heating and stirring. The polymerization temperature is 70°C, and the reaction time is 24 hours. . After the polymerization reaction is completed, use 100mL of methanol and acetic acid mixed solution with a volume ratio of 9:1 to extract the synthesized polymer by Soxhlet extraction to remove the template molecules, and then extract it with pure methanol. Acetic acid molecule. After the extraction, the polymer is placed in a vacuum drying oven to dry to constant weight, and finally the progesterone