The invention relates to the technical field of sample filtration for instrumental analysis and provides a sample filter device for instrumental analysis. The sample filter device comprises a solutionfilter chamber which comprises an external cylindrical shell, a cylindrical filter barrel is embedded in the external cylindrical shell, and supporting columns are arranged on the inner bottom face of the external cylindrical shell. The upper end of the solution filter chamber is connected with a seal cover, a rotating rod is mounted in the middle of the lower side of the seal cover, stirring blades are mounted at the tail end of the rotating rod, and a rocker is arranged in the middle of the upper side of the seal cover. A pressurizing air cylinder is mounted at the upper end of a supportingplate which is mounted on the lower side wall of the solution filter chamber. By arrangement of the two-layer solution filter chamber, convenience in thorough filtration of liquid is achieved; by arrangement of the stirring blades and the rotating rod, impurity precipitation and attachment are avoided; by arrangement of the pressurizing air cylinder, the filter speed is increased. The sample filter device is simple in structure, capable of filtering instrumental analysis samples, high in filter speed and great in filter effect.