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3 results about "Antibiosis" patented technology

Antibiosis is a biological interaction between two or more organisms that is detrimental to at least one of them; it can also be an antagonistic association between an organism and the metabolic substances produced by another. Examples of antibiosis include the relationship between antibiotics and bacteria or animals and disease-causing pathogens. The study of antibiosis and its role in antibiotics has led to the expansion of knowledge in the field of microbiology. Molecular processes such cell wall synthesis and recycling, for example, have become better understood through the study of how antibiotics affect beta-lactam development through the antibiosis relationship and interaction of the particular drugs with the bacteria subjected to the compound.

Novel inhibitors of beta-lactamase

InactiveUS20100279983A1BiocideAntibacterial agentsAntibiosisAryl
This invention provides novel β-lactamase inhibitors of the aryl- and heteroarylsulfonamidomethylphosphonate monoester class having nitrogen-based cations or quarternary ammonium groups. The compounds inhibit three classes of β-lactamases and synergize the antibacterial effects of β-lactam antibiotics (e.g., imipenem and ceftazidime) against those micro-organisms normally resistant to the β-lactam antibiotics as a result of the presence of the β-lactamases. Formula (I) or pharmaceutically acceptable salt thereof.
Owner:METHYLGENE
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