The invention provides a self-activation vanadate fluorescent powder, a preparation method, and applications thereof. The chemical formula of the self-activation vanadate fluorescent powder is A2BMg2V3O12, wherein the A represents Li, Na, or K, and the B represents Y, Gd, Bi, La, or Lu. The self-activation vanadate fluorescent powder is synthesized through a sol-gel method, and can be activated by ultraviolet lights with a wave length of 200 to 400 nm. The emission spectrum of the fluorescent powder covers a wide range of 350 to 700 nm, and the main peak is at 500 nm. The light emission of the self-activation vanadate fluorescent powder can be adjusted by doping rare earth ions such as Eu3+, Sm3+, Yb3+, Pr3+, Nd3+, and the like. The fluorescent powder can be applied to the fields of LED and solar cells.