The invention discloses a new method for synthesizing dithieno[2,3-b:4',3'-d] silole derivative with the characteristic of an unsymmetrical structure. The method comprises the following steps of: performing
bromine and
lithium exchange reaction of 4,4'-
bromine-2,2,5,5'-
tetra(
trimethylsilyl)-3,3'-bithiophene serving as a
raw material and
tertiary butyl lithium in absolute
ether, and
quenching by using water at the temperature of -50 DEG C to obtain 7,7-dimethyl-2,4,6-tri(
trimethylsilyl)-dithieno[2,3-b:4',3'-d]silole in high yield; and
quenching by using the water at the temperature of 45 DEG C to obtain 7,7-dimethyl-4,6-bis(
trimethylsilyl)-dithieno[2,3-b:4',3'-d]silole in high yield. The synthetic process has
operability and is suitable for laboratory-scale preparation, and reaction is performed in the absence of water and
oxygen at low temperature.