A process of manufacturing of
Rosuvastatin Potassium of formula (I)is disclosed. The process comprises the steps of(a) treating
Rosuvastatin protected compound of formula (II)wherein R1 and R2 are same or different having C1-C4
carbon atom or
hydrogen or R1 and R2 can combine together to afford a cyclic structure comprising a junction atom as carbon or
metal atom such as Si (
silicon);with an inorganic base of the kind such as herein described having
potassium as cation in a suitable
solvent to form
Rosuvastatin potassium;(b) isolating Rosuvastatin
potassium.