2 results about "Systemic lupus" patented technology

The invention discloses a method for determining correlation between single nucleotide polymorphisms rs4840568 and rs13277113 of Han people in Chinese Mainland and systemic lupus erythematosus (SLE). The method comprises that through a non-labeled probe high-resolution solubility curve method, a SLE patient is subjected to genetic typing so that the correlation between single nucleotide polymorphisms rs4840568 and rs13277113 of Han people in Chinese Mainland and SLE is determined. At present, it is proved that environmental factors and gene factors produce important effects in SLE generation and development and thus a research result obtained by the method provides a theoretical basis for in-depth knowledge of SLE diseases.

Provided are a pharmaceutical use of poly-gamma-glutamic acid used for preventing or treating Th17-mediated diseases, a composition for preventing or treating Th17-mediated diseases comprising poly-gamma-glutamic acid as an active ingredient, and a method of preventing or treating Th17-mediated diseases using the same. The pharmaceutical composition is effective in inhibiting the differentiation of Th17 cells while promoting Treg cells, and, thus, can be useful in preventing or treating Th17-mediated diseases such as multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, Crohn's disease, ankylosing spondylitis, and the like.