Model teaching tool for action mode among superantigen, MHC and TCR

A technology of model teaching aids and superantigens, applied in the field of teaching aids, can solve problems such as inability to analyze the structure well, and achieve the effects of saving transportation costs, convenient operation and simple structure

Inactive Publication Date: 2015-06-17
SUZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the field of teaching, schematic diagrams are generally used to show the mode of action of superantigens, MHC, and TCR, but flat pictures cannot analyze their structures well and explain their process of action, so a three-dimensional model is needed for auxiliary explanations

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Such as Figure 1-3 As shown, the model teaching aid of superantigen, MHC and TCR, including two semicircular bases 1, four cylindrical first columns 2, and four cylindrical second columns 3 with arc-shaped openings , four strip-shaped first connecting rods 4, ten strip-shaped second connecting rods 5, one strip-shaped third connecting rod 6, an ellipsoidal central body 8, an arc-shaped body 7, one Spherical insert 9, the two ends of the first cylinder 2 are respectively provided with a connection hole 10, and the side is symmetrically provided with two connection holes 10, and the two ends of the second cylinder 3 are respectively provided with a connection hole 10, and the side is symmetrically provided with two connection holes. Two connecting holes 10, two ends of the arc body 7 are provided with connecting rods, one end of the spherical insert 9 is provided with a connecting rod, and the top surface of the seat body 1 is provided with two connecting holes 10; The ...

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PUM

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Abstract

The invention discloses a model teaching tool for an action mode among superantigen, MHC and TCR. The model teaching tool comprises two seat bodies, a central body, four second pillar bodies and four first pillar bodies, wherein the two seat bodies are oppositely arranged, the central body is arranged between the two seat bodies and is packaged by the four second pillar bodies, and the four first pillar bodies are arranged at two ends of the four second pillar bodies two by two and are respectively connected with the two seat bodies through four first connecting rods. The model teaching tool is simple in structure, convenient to operate, vivid and visual, the packaging space is reduced, and the transportation cost is saved.

Description

technical field [0001] The invention relates to the field of teaching aids, in particular to teaching aids for model teaching aids of superantigens, MHC and TCR. Background technique [0002] Typically, common protein antigens can activate one in 10,000 to one in a million T cells in the body's total T cell pool. However, some substances only need a very low concentration (1~10ng / ml) to activate 2%~20% of T cell clones and generate a strong immune response. This type of antigen is called a superantigen (SAg), which is different from ordinary Protein antigens are different. One end of SAg can directly bind to the outer region of the Vβ chain CDR3 of TCR to activate T cells in the form of a complete protein, and the other end can bind to the outside of the antigen-binding groove (cleft) of MHC class II molecules on the surface of antigen-presenting cells, so SAg cannot Recognition of CDRα and TCRα involved in Vβ are also not restricted by MHC. The T cell response induced by...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G09B23/26
CPCG09B23/26
Inventor 赵英伟朱越雄
Owner SUZHOU UNIV
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