Pharmaceutical composition for treating digestive system disease

[0040] Example 1: Preparation of the lansoprazole enteric-coated tablet composition of the present invention

[0041] Tablet core prescription (parts by weight): 10 parts lansoprazole, 49 parts lactose, 15 parts microcrystalline cellulose, 8.5 parts potassium sodium tartrate, 7 parts crospovidone, 1 part povidone K30, 95% ethanol 20 parts, 0.6 parts of polysorbate 80, 1 part of finely powdered silica gel.

[0042] Enteric coating formulation (parts by weight): 5.2 parts of hypromellose phthalate, 0.5 parts of n-butyl stearate, 1.5 parts of talc, 140 parts of 95% ethanol.

[0043] Preparation:

[0044] The enteric-coated tablet composition of the present invention can be prepared by methods commonly used in the art, including but not limited to the following preparation methods:

[0045] 1) Preparation of tablet core

[0046] The prescription amount of lansoprazole raw material and lactose, microcrystalline cellulose, potassium sodium tartrate, and crospovidone are sieved and mixed, and the

[0051] Example 2: Preparation of the lansoprazole enteric-coated tablet composition of the present invention

[0052] Tablet core prescription (parts by weight): 14 parts lansoprazole, 52 parts lactose, 17 parts microcrystalline cellulose, 9.8 parts potassium sodium tartrate, 10 parts crospovidone, 1.5 parts povidone K30, 95% ethanol 22 parts, 0.7 parts of polysorbate 80,

[0053] Micro-powder silica gel 1.2 parts.

[0054] Enteric coating formulation (parts by weight): 6.4 parts of hypromellose phthalate, 0.6 parts of n-butyl stearate, 2.0 parts of talc, and 145 parts of 95% ethanol.

[0055] Preparation:

[0056] The enteric-coated tablet composition of the present invention can be prepared by methods commonly used in the art, including but not limited to the following preparation methods:

[0057] 1) Preparation of tablet core

[0058] The prescription amount of lansoprazole raw material and lactose, microcrystalline cellulose, potassium sodium tartrate, and crospovidone are sieved and m

[0063] Example 3: Preparation of the lansoprazole enteric-coated tablet composition of the present invention

[0064] Tablet core prescription (parts by weight): 15.7 parts of lansoprazole, 54.5 parts of lactose, 20.0 parts of microcrystalline cellulose, 10.5 parts of potassium sodium tartrate, 12.0 parts of crospovidone, 1.9 parts of povidone K30, 95% ethanol 24.1 parts, 0.8 parts of polysorbate 80, 1.5 parts of micro-powder silica gel.

[0065] Enteric coating formulation (parts by weight): 7.4 parts of hypromellose phthalate, 0.9 parts of n-butyl stearate, 2.4 parts of talc, and 150 parts by 95% ethanol.

[0066] Preparation:

[0067] The enteric-coated tablet composition of the present invention can be prepared by methods commonly used in the art, including but not limited to the following preparation methods:

[0068] 1) Preparation of tablet core

[0069] The prescription amount of lansoprazole raw material and lactose, microcrystalline cellulose, potassium sodium tartrate, and crosp