Cell complex used for periodontal tissue repairing, and applications thereof

A periodontal tissue and complex technology, which is applied in the field of periodontal tissue repair cell complexes and its preparation, can solve the problems of non-seed cells, low stem cell content, large body trauma, etc., and achieves abundant sources and promotes periodontal tissue. Repair and reduce trauma

Active Publication Date: 2016-01-20
GUANGZHOU SALIAI STEMCELL SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technology uses umbilic Cord Mesenchyma Stem Cells (UCMCs) from dentritis patients' teeth that are used to healing or regenerating damaged areas around their teeth. These UCMScells have been found effective at promoting wound-healing processes while also being safe compared to other methods like autologous blood clotting techniques. Additionally, these UCSCs combine with periodontoid sinus osteomyclasts to stimulate cartilage growth without causing damage during surgery procedures. Overall, this method provides an improved treatment option for periodonetitis caused due to gingival recession syndrome.

Problems solved by technology

This patented technical problem addressed in this patents relates to finding ways to improve dental therapy for treating chronically infected gingivitis caused by plaque buildup on gums during orthodontics procedures without causing significant discomfort or damaging surrounding soft tissue structures such as tendons and muscles.

Method used

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  • Cell complex used for periodontal tissue repairing, and applications thereof
  • Cell complex used for periodontal tissue repairing, and applications thereof
  • Cell complex used for periodontal tissue repairing, and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1. Cell complex for periodontal tissue repair

[0020] In this example, 2.5×10 umbilical cord mesenchymal stem cells are contained in the cell complex for periodontal tissue repair per milliliter 4 each, periodontal ligament mesenchymal stem cells 2.5×10 4 Each, the mass volume percentage of human serum albumin (Austria Baxter International Co., Ltd.) is 1.5%, and the balance is normal saline.

Embodiment 2

[0021] Example 2. Cell complex for periodontal tissue repair

[0022] In this example, 0.5×10 umbilical cord mesenchymal stem cells are contained in the cell complex for periodontal tissue repair per milliliter 4 5 × 10 periodontal ligament mesenchymal stem cells 4 Each, the mass volume percentage of human serum albumin is 2%, and the balance is normal saline.

Embodiment 3

[0023] Example 3. Cell complex for periodontal tissue repair

[0024] In this example, 5 × 10 umbilical cord mesenchymal stem cells are contained in the cell complex for periodontal tissue repair per milliliter 4 each, periodontal ligament mesenchymal stem cells 0.5×10 4 Each, the mass volume percentage of human serum albumin is 1%, and the balance is normal saline.

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Abstract

The invention discloses a cell complex used for periodontal tissue repairing, and applications thereof. The cell complex comprises 0.5*10<4> to 5*10<4>/ml human umbilical cord mesenchymal stem cells and 0.5*10<4> to 5*10<4>/ml periodontal ligament mesenchymal stem cells. The cell complex can be used for preparing drugs used for periodontal tissue repairing. The cell complex composed of human umbilical cord mesenchymal stem cells and periodontal ligament mesenchymal stem cells is capable of inhibiting expression of inflammatory factors obviously, and possesses obvious effects on periodontal tissue repairing.

Description

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Claims

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Application Information

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Owner GUANGZHOU SALIAI STEMCELL SCI & TECH CO LTD
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