Ruler scratching device used for wound healing cell experiments

A wound healing and scratching technology, used in tissue cell/virus culture devices, biochemical cleaning devices, enzymology/microbiology devices, etc., can solve problems such as irregularity, poor repeatability, and inability to guarantee consistency , to achieve the effect of improving repeatability

Active Publication Date: 2017-03-22
WEST CHINA HOSPITAL SICHUAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This new technology helps make experiments more accurate by ensuring that every single step taken during an experiment remains smoothly done without damaging any parts or affects it's final outcome. By matching the guiding grooves for both scratchers and scratch-off blocks, this innovation makes research easier while maintaining accuracy.

Problems solved by technology

This patented technical problem addressed by the patents relates to studying how well different types of tissue can move towards one another during normal physiological processes such as blood flow or nerve growth. Traditional methods are often imprecise due to their lacking reproducibility and roughness caused by imperfections on the surface being analyzed.

Method used

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  • Ruler scratching device used for wound healing cell experiments
  • Ruler scratching device used for wound healing cell experiments
  • Ruler scratching device used for wound healing cell experiments

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] like figure 1 As shown, the scratch device for wound healing cell experiments disclosed in this embodiment includes a strip-shaped scratch guide block 1, the scratch guide block 1 has a guide groove 2 running through its top surface and bottom surface, and the guide groove 2 The guide surface is a vertical plane. Preferably, the guide groove 2 is a rectangular through groove.

[0036] This embodiment also discloses a culture plate 4 and a scratcher 6 used together with the scratch guide block 1 . The culture plate 4 has a culture hole 5 , and the inner diameter of the culture hole 5 is equal to the length of the scratch guide block 1 . The scratcher 6 is strip-shaped, the thickness of the scratcher 6 is smaller than the width of the guide groove 2 , and the length of the scratcher 6 is greater than the depth of the guide groove 2 . Of course, a 6-well plate can also be used instead of the culture plate 4 of the present invention. The end of the scratcher 6 is a flat smo

Embodiment 2

[0047] The difference between this embodiment and Embodiment 1 is that the scratch guide block 1 includes two guide plates 11 , the two guide plates 11 are facing each other, and the opposite ends of the two guide plates 11 are fixedly connected by the connecting portion 12 . In this embodiment, the connection portion 12 is plate-shaped, the height of the connection portion 12 is the same as that of the guide plate 11 , and the bottom surface of the connection portion 12 is flush with the bottom surface of the guide plate 11 .

[0048] Preferably, the scratch guide block 1 is manufactured in one piece. In order to reduce the influence of human factors, the height of the connecting part 12 is the same as that of the guide plate 11, and the bottom surface of the connecting part 12 is flush with the bottom surface of the guide plate 11, so as to ensure that the length drawn each time is the same. The length of the guide plate 11 is 34.6mm-35mm; the thickness of the guide plate 11 is

Embodiment 3

[0050] The difference between this embodiment and embodiment 2 is that the scratching guide block 1 is not manufactured in one piece, but the two guide plates 11 are connected by glue, that is, the connecting part 12 is made of glue.

[0051] The invention utilizes the guide groove to ensure the consistency of each scratch and improve the repeatability of the experiment.

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Abstract

The invention relates to a ruler scratching device used for wound healing cell experiments. The ruler scratching device comprises a strip-shaped scratching guide block with a guide groove penetrating through the top face and the bottom face of the scratching guide block; the guide face of the guide groove is a vertical plane; supporting arms are installed on the outer side walls of the long edges of the scratching guide block; intervals are reserved between the supporting arms and the bottom face of the scratching guide block; the supporting arms are parallel with the horizontal direction; and the two supporting arms are located on the same straight line. It can be ensured that scratching widths are consistent every time through the guide groove, and experiment repeatability is improved.

Description

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Claims

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Application Information

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Owner WEST CHINA HOSPITAL SICHUAN UNIV
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