Inhibitor for blood glucose level increase and oral composition comprising same
A technology of blood sugar level and inhibitor, applied in the field of oral composition, to achieve the effect of inhibiting the rise of blood sugar level and using a wide range
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[0031] The present invention relates to an invention related to a blood sugar level rise inhibitor comprising a branched α-glucan mixture characterized by the following (A) to (C) as an active ingredient.
[0032] (A) with glucose as the constituent sugar,
[0033] (B) Glucose having a non-reducing terminal glucose residue at one end of a linear glucan with a degree of polymerization of 3 or more glucose linked via an α-1,4 bond via a bond other than an α-1,4 bond A branched structure with a degree of polymerization above 1,
[0034] (C) Isomaltose is produced by isomaltoglucanase digestion.
[0035] The blood-sugar-level rise inhibitor referred to in this specification is an agent which suppresses the rise of the blood-sugar level after the ingestion of a human monosaccharide.
[0036] In addition, the ingestion mentioned in this specification means taking into a human body, and includes both the ingestion by the oral route and the ingestion by the infusion route.
[0037] Th
Embodiment 1
[0134]
[0135] According to the method described in Example 5 of International Publication No. WO2008 / 136331 pamphlet, branched α-glucan mixture powder was prepared. Furthermore, the obtained branched α-glucan mixture powder has the following characteristics (a) to (g).
[0136] (a) with glucose as the constituent sugar,
[0137] (b) Glucose polymerization having a non-reducing terminal glucose residue attached to one end of a linear glucan with a degree of polymerization of 3 or more glucose linked via an α-1,4 bond via a bond other than an α-1,4 bond A branch structure with a degree of 1 or more,
[0138] (c) isomaltose is digested by isomaltoglucanase to produce isomaltose at 35% by mass per solid of the digestate,
[0139] (d) The water-soluble dietary fiber content is 80.8% by mass,
[0140] (e) The ratio of α-1,4 bonded glucose residues to α-1,6 bonded glucose residues is 1:2.2,
[0141] (f) The total of α-1,4 bonded glucose residues and α-1,6 bonded glucose residu
Embodiment 2
[0145]
[0146]According to the method described in Experiment 2-2 of International Publication No. WO2008 / 136331 pamphlet, a branched α-glucan mixture solution having a solid content concentration of 30% by mass was prepared, and then spray-dried according to a conventional method to obtain a branched α-glucan solution. Polysaccharide mixture powder. Furthermore, the obtained branched α-glucan mixture powder has the following characteristics (a) to (g).
[0147] (a) with glucose as the constituent sugar,
[0148] (b) Glucose polymerization having a non-reducing terminal glucose residue attached to one end of a linear glucan with a degree of polymerization of 3 or more glucose linked via an α-1,4 bond via a bond other than an α-1,4 bond A branch structure with a degree of 1 or more,
[0149] (c) isomaltose is produced by digestion with isomaltoglucanase at 27.2% by mass per solid of the digestate,
[0150] (d) The water-soluble dietary fiber content is 41.8% by mass,
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