Inhibitor for blood glucose level increase and oral composition comprising same

A technology of blood sugar level and inhibitor, applied in the field of oral composition, to achieve the effect of inhibiting the rise of blood sugar level and using a wide range

Inactive Publication Date: 2018-05-11
HAYASHIBARA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This patented technology describes how certain substances called alpha -gum are found naturally occurring on plants that have been used for food production. These natural products help reduce high levels of sugars while being less harmful than other sweeteners like sucrose. They also lower their glycemic index compared to regular tablets without them making pills easier to swallow even if they contain too much calories. By adding these materials into chewing gums, individuals who consume large amounts may experience fewer negative health consequences from eating excessive quantities of carbohydrates due to increased risk of developing dentritis caused by overconsumption of starches during meals containing this type of product.

Problems solved by technology

This patent describes methods aiming towards reducing elevated blood sugar concentration during eatings while avoiding excessive consumption due to increased risk factors associated with metabolism related diseases including obesity and hyperlipemia. Existing techniques involve giving up certain carbohydrate sources called sucrose, glycerol, or invertase in chewing cereal bars. These approaches may result in decreased nutrients being consumptively gained throughout their body. Therefore, alternative strategies involving increasing the content of specific types of saccharidics within food items would provide more effective ways to reduce inflammation caused by enzyme activity.

Method used

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  • Inhibitor for blood glucose level increase and oral composition comprising same
  • Inhibitor for blood glucose level increase and oral composition comprising same
  • Inhibitor for blood glucose level increase and oral composition comprising same

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Experimental program
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Embodiment approach

[0031] The present invention relates to an invention related to a blood sugar level rise inhibitor comprising a branched α-glucan mixture characterized by the following (A) to (C) as an active ingredient.

[0032] (A) with glucose as the constituent sugar,

[0033] (B) Glucose having a non-reducing terminal glucose residue at one end of a linear glucan with a degree of polymerization of 3 or more glucose linked via an α-1,4 bond via a bond other than an α-1,4 bond A branched structure with a degree of polymerization above 1,

[0034] (C) Isomaltose is produced by isomaltoglucanase digestion.

[0035] The blood-sugar-level rise inhibitor referred to in this specification is an agent which suppresses the rise of the blood-sugar level after the ingestion of a human monosaccharide.

[0036] In addition, the ingestion mentioned in this specification means taking into a human body, and includes both the ingestion by the oral route and the ingestion by the infusion route.

[0037] Th

Embodiment 1

[0134]

[0135] According to the method described in Example 5 of International Publication No. WO2008 / 136331 pamphlet, branched α-glucan mixture powder was prepared. Furthermore, the obtained branched α-glucan mixture powder has the following characteristics (a) to (g).

[0136] (a) with glucose as the constituent sugar,

[0137] (b) Glucose polymerization having a non-reducing terminal glucose residue attached to one end of a linear glucan with a degree of polymerization of 3 or more glucose linked via an α-1,4 bond via a bond other than an α-1,4 bond A branch structure with a degree of 1 or more,

[0138] (c) isomaltose is digested by isomaltoglucanase to produce isomaltose at 35% by mass per solid of the digestate,

[0139] (d) The water-soluble dietary fiber content is 80.8% by mass,

[0140] (e) The ratio of α-1,4 bonded glucose residues to α-1,6 bonded glucose residues is 1:2.2,

[0141] (f) The total of α-1,4 bonded glucose residues and α-1,6 bonded glucose residu

Embodiment 2

[0145]

[0146]According to the method described in Experiment 2-2 of International Publication No. WO2008 / 136331 pamphlet, a branched α-glucan mixture solution having a solid content concentration of 30% by mass was prepared, and then spray-dried according to a conventional method to obtain a branched α-glucan solution. Polysaccharide mixture powder. Furthermore, the obtained branched α-glucan mixture powder has the following characteristics (a) to (g).

[0147] (a) with glucose as the constituent sugar,

[0148] (b) Glucose polymerization having a non-reducing terminal glucose residue attached to one end of a linear glucan with a degree of polymerization of 3 or more glucose linked via an α-1,4 bond via a bond other than an α-1,4 bond A branch structure with a degree of 1 or more,

[0149] (c) isomaltose is produced by digestion with isomaltoglucanase at 27.2% by mass per solid of the digestate,

[0150] (d) The water-soluble dietary fiber content is 41.8% by mass,

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Abstract

The present invention addresses the problem of providing an inhibitor for blood glucose level increase, which can be daily, easily, safely and continuously taken after the intake of a monosaccharide by those who are worrying about blood glucose level including healthy persons, and an oral composition comprising the same. To solve this problem, provided are: an inhibitor for blood glucose level increase that comprises a branched [alpha]-glucan mixture characterized by (A) comprising glucose as a constituent sugar, (B) having a branched structure of a glucose polymerization degree of 1 or higherthat is bonded, via a bond other than an [alpha]-1,4 bond, to a non-reducing terminal glucose residue positioned at one end of a linear glucan bonded via an [alpha]-1,4 bond and having a glucose polymerization degree of 3 or higher, and (C) forming isomaltose when digested by isomaltodextranase; and an oral composition that comprises the inhibitor for blood glucose level increase together with amonosaccharide.

Description

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Claims

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Application Information

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Owner HAYASHIBARA CO LTD
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