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2 results about "Antiviral drug" patented technology

Antiviral drugs are a class of medication used specifically for treating viral infections rather than bacterial ones. Most antivirals are used for specific viral infections, while a broad-spectrum antiviral is effective against a wide range of viruses. Unlike most antibiotics, antiviral drugs do not destroy their target pathogen; instead they inhibit their development.

Application of cirsimaritin in preparing antiviral drug

ActiveCN106491583AInhibition of lesionsReduced expression levelOrganic active ingredientsAntiviralsCytopathic effectAmantadine
The invention relates to the technical field of medicines, in particular to application of cirsimaritin in preparing an antiviral drug. The invention for the first time proposes that the cirsimaritin has definite resistance to an influenza virus. The cirsimaritin can significantly inhibit a cytopathic effect caused by the influenza virus infection, and median inhibitory concentrations to an influenza virus A / FortMonmouth / 1 / 1947 and an influenza virus A / jinnan / 15 / 2009 are equivalent to that of an influenza virus Amantadine and an influenza virus Ribavirin; meanwhile, the cirsimaritin can significantly inhibit the expression of influenza virus specific protein M2 protein, and lower an expression level of influenza virus RNA; the intensities of inhibition functions of 40 microgrammes per milliliter of the cirsimaritin on expression of the influenza virus M2 protein and expression of the influenza virus RNA are equivalent to that of 10 micrometers of the Ribavirin, showing that intensity of the anti-influenza virus effect of the cirsimaritin is close to that of antiviral drugs currently commonly used in clinic, and application of the cirsimaritin in preparing anti-influenza drugs has a good prospect.
Owner:XINJIANG INST OF MATERIA MEDICA
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