3 results about "Specific protein" patented technology

The invention relates to a method of detecting and quantifying small peptides derived from proteins from a range of different clinical samples using the Selective Reaction Monitoring (SRM) profiling technique. By targeting these unique peptides which specifically identify particular proteins, the present invention enables multiple samples to be run in a multiplexed fashion in order to identify, diagnose, quantitate and profile a full range of benign and pathologic entities, including but not limited to, the complete range of cancers and the spectrum of inflammatory diseases, including inflammatory cell typing and bone marrow cell typing. The SRM assay is capable of performing clinical blood typing and it can also act as a diagnostic test to identify women at highest risk for cervical cancer base on Human Papillomavirus (HPV) testing.

The invention relates to the technical field of medicines, in particular to application of cirsimaritin in preparing an antiviral drug. The invention for the first time proposes that the cirsimaritin has definite resistance to an influenza virus. The cirsimaritin can significantly inhibit a cytopathic effect caused by the influenza virus infection, and median inhibitory concentrations to an influenza virus A / FortMonmouth / 1 / 1947 and an influenza virus A / jinnan / 15 / 2009 are equivalent to that of an influenza virus Amantadine and an influenza virus Ribavirin; meanwhile, the cirsimaritin can significantly inhibit the expression of influenza virus specific protein M2 protein, and lower an expression level of influenza virus RNA; the intensities of inhibition functions of 40 microgrammes per milliliter of the cirsimaritin on expression of the influenza virus M2 protein and expression of the influenza virus RNA are equivalent to that of 10 micrometers of the Ribavirin, showing that intensity of the anti-influenza virus effect of the cirsimaritin is close to that of antiviral drugs currently commonly used in clinic, and application of the cirsimaritin in preparing anti-influenza drugs has a good prospect.