The invention discloses a traditional Chinese medicine granule preparation for treating hepatic calculus and a preparation method thereof. The preparation is prepared from the following medicinal materials in parts by weight: 32-51 parts of herba artemisiae scopariae, 26-43 parts of rhizoma alismatis, 19-31 parts of felwort, 21-37 parts of radix bupleuri, 18-30 parts of corydalis tuber, 14-27 parts of lysimachia christinae hance, 11-19 parts of lonicera japonica, 8-16 parts of ligusticum wallichii, 7-13 parts of Chinese gall, 1-5 parts of red halloysite, 2-9 parts of fructus evodiae, 1-8 parts of concha arcae and 3-8 parts of bulbus fritillariae thunbergii. The preparation is reasonable in formula and convenient and safe to take, no toxic or side effect is discovered, and clinical verification proves that the preparation has exact and remarkable curative effects. Years of clinical observation indicates that the preparation has the functions of nourishing yin to calm the liver, nourishing yin, reducing internal fire, diminishing inflammation, relieving bladder and eliminating stone, and has an effective rate of over 90 percent when used for treating cholecystolithiasis and hepatolithiasis due to liver-yin deficiency and interior dampness-heat.